| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L031401
BDB031401
|
US20230338337, Example 52
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1CCC1CO)c1ccc(Cl)cc1
|
C30H31Cl2NO4 540.487000 |
YJPCYIKTKXDGAX-MWZSVNGBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628576; PubChem:CID135281746
|
Local ready
Direct docking supported
|
|
E3L031402
BDB031402
|
BDBM628600
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C28H28Cl2N2O4 527.448000 |
OHVDALOYPVPNFX-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628600; PubChem:CID135282822
|
Local ready
Direct docking supported
|
|
E3L031403
BDB031403
|
BDBM628601
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C24H22Cl2N2O3 457.357000 |
VPQDHGOWYYJJGJ-XMMPIXPASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628601; PubChem:CID135282610
|
Local ready
Direct docking supported
|
|
E3L031404
BDB031404
|
BDBM628602
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCCO)c1ccc(Cl)cc1
|
C25H24Cl2N2O4 487.383000 |
MEKDRXZAXUKWMV-RUZDIDTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628602; PubChem:CID135282424
|
Local ready
Direct docking supported
|
|
E3L031405
BDB031405
|
BDBM628603
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCCCO)c1ccc(Cl)cc1
|
C26H26Cl2N2O4 501.410000 |
APJJOBUJRSBACO-AREMUKBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628603; PubChem:CID135282812
|
Local ready
Direct docking supported
|
|
E3L031406
BDB031406
|
BDBM628604
CC(C)(O)CCO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H30Cl2N2O4 529.464000 |
FSCVGUSPECTPQR-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628604; PubChem:CID135282886
|
Local ready
Direct docking supported
|
|
E3L031407
BDB031407
|
BDBM628605
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(O)CC1)c1ccc(Cl)cc1
|
C27H26Cl2N2O4 513.421000 |
SQIIIVNSWACUOK-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628605; PubChem:CID135283034
|
Local ready
Direct docking supported
|
|
E3L031408
BDB031408
|
BDBM628606
CC1CC1(O)[C@@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H25Cl2FN2O3 515.412000 |
VOBQSAHXYSXSNJ-KDCDNYMMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628606
|
Local ready
Direct docking supported
|
|
E3L031409
BDB031409
|
BDBM628607
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCCS(C)(=O)=O)c1ccc(Cl)cc1
|
C26H26Cl2N2O5S 549.476000 |
BGVAEISUXZWVFA-AREMUKBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628607; PubChem:CID135282579
|
Local ready
Direct docking supported
|
|
E3L031410
BDB031410
|
BDBM628608
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C24H21Cl2FN2O3 475.347000 |
BVJUWGFCXNBCMN-XMMPIXPASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628608; PubChem:CID135282801
|
Local ready
Direct docking supported
|
|
E3L031411
BDB031411
|
BDBM628609
CCc1ccc([C@@]2(OCC3(CO)CC3)c3ccc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cn2)cc1
|
C30H33ClN2O4 521.057000 |
GXZPPIBHFZDNJB-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628609; PubChem:CID135282895
|
Local ready
Direct docking supported
|
|
E3L031412
BDB031412
|
BDBM628610
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1F
|
C28H27Cl2FN2O4 545.438000 |
FDNWIUCFHNTFKW-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628610
|
Local ready
Direct docking supported
|
|
E3L031413
BDB031413
|
BDBM628611
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)c[n+]1[O-])[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C28H28Cl2N2O5 543.447000 |
JZNFZVXUISXDJZ-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628611
|
Local ready
Direct docking supported
|
|
E3L031414
BDB031414
|
BDBM628612
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@@H]1CC[C@@H](O)C1)c1ccc(Cl)cc1
|
C28H28Cl2N2O4 527.448000 |
AFDYIUDAHGVFFG-MVOZIGHISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628612; PubChem:CID135282522
|
Local ready
Direct docking supported
|
|
E3L031415
BDB031415
|
BDBM628613
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@H]1CCS(=O)(=O)C1)c1ccc(Cl)cc1
|
C27H26Cl2N2O5S 561.487000 |
GNSVNDPZIYSMAM-WXVAWEFUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628613; PubChem:CID169490039
|
Local ready
Direct docking supported
|
|
E3L031416
BDB031416
|
BDBM628614
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@@H]1CCS(=O)(=O)C1)c1ccc(Cl)cc1
|
C27H26Cl2N2O5S 561.487000 |
GNSVNDPZIYSMAM-AJTFRIOCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628614; PubChem:CID169490040
|
Local ready
Direct docking supported
|
|
E3L031417
BDB031417
|
BDBM628615
CC1CC1(O)[C@@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(C)O)cc2C(=O)N1Cc1ccc(C#N)cn1
|
C28H25ClFN3O3 505.977000 |
RTZCVEAPQNLWPL-LZIYAXBJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628615
|
Local ready
Direct docking supported
|
|
E3L031418
BDB031418
|
BDBM628616
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@H]1CC[C@@H](O)C1)c1ccc(Cl)cc1
|
C28H28Cl2N2O4 527.448000 |
AFDYIUDAHGVFFG-AWVRMFGXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628616; PubChem:CID137512971
|
Local ready
Direct docking supported
|
|
E3L031419
BDB031419
|
BDBM628617
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@@H]1CC[C@H](O)C1)c1ccc(Cl)cc1
|
C28H28Cl2N2O4 527.448000 |
AFDYIUDAHGVFFG-SXDGJLEOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628617; PubChem:CID137513639
|
Local ready
Direct docking supported
|
|
E3L031420
BDB031420
|
BDBM628618
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@H]1CC[C@H](O)C1)c1ccc(Cl)cc1
|
C28H28Cl2N2O4 527.448000 |
AFDYIUDAHGVFFG-UXWDXCIHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628618; PubChem:CID135282412
|
Local ready
Direct docking supported
|