| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L031481
BDB031481
|
BDBM628696
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OC[C@H]1C[C@@H](O)C1)c1ccc(Cl)cc1
|
C29H27ClFN3O4 536.003000 |
BMTZOKAZWFZZTA-BDOPKQKUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628696
|
Local ready
Direct docking supported
|
|
E3L031482
BDB031482
|
BDBM628697
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CC3CCOCC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C29H30Cl2N2O4 541.475000 |
KCYGLOPLXSALQP-YPJJGMIRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628697; PubChem:CID135282778
|
Local ready
Direct docking supported
|
|
E3L031483
BDB031483
|
BDBM628698
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)COCCO)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C26H26Cl2N2O5 517.409000 |
IFLBFEDCNOOTHF-FXDYGKIASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628698; PubChem:CID135282440
|
Local ready
Direct docking supported
|
|
E3L031484
BDB031484
|
BDBM628699
CC(O)(CN1CCNCC1)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1
|
C32H34Cl2FN5O4 642.559000 |
ROPGGEFPJZUROS-BDJZEIKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628699
|
Local ready
Direct docking supported
|
|
E3L031485
BDB031485
|
BDBM628701
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)c3cnn(C)c3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H24Cl2N4O3 523.420000 |
ORTBVXWNGSRDOY-SSYAZFEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628701; PubChem:CID135282288
|
Local ready
Direct docking supported
|
|
E3L031486
BDB031486
|
BDBM628702
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)c3ccc[n+]([O-])c3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H23Cl2N3O4 536.415000 |
JNUWWHYUCZGJMZ-PLYLYKGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628702; PubChem:CID137497985
|
Local ready
Direct docking supported
|
|
E3L031487
BDB031487
|
BDBM628703
COc1cc(C(C)(O)c2ccc3c(c2)C(=O)N(Cc2ccc(Cl)cn2)[C@@]3(OC)c2ccc(Cl)cc2)ccn1
|
C29H25Cl2N3O4 550.442000 |
VWRFSWFTDYZYAM-YPJJGMIRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628703; PubChem:CID135282809
|
Local ready
Direct docking supported
|
|
E3L031488
BDB031488
|
BDBM628705
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3CCN(C(C)=O)CC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H32Cl2N4O4 583.516000 |
ULRBOSOOAALUIH-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628705; PubChem:CID135282323
|
Local ready
Direct docking supported
|
|
E3L031489
BDB031489
|
BDBM628706
N#Cc1ccc(N2C(=O)c3cccc(F)c3C2(OCC2CC(O)C2)c2ccc(Cl)cc2)nc1
|
C25H19ClFN3O3 463.896000 |
IHLCFOUCOBGRNX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628706
|
Local ready
Direct docking supported
|
|
E3L031490
BDB031490
|
BDBM628726
CN1CCN(CC(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cn2)[C@@]3(OCC2(C(N)=O)CC2)c2ccc(Cl)cc2)CC1
|
C33H36Cl2FN5O4 656.586000 |
UCCXFOMKSHEVLC-NFCCVXSLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628726
|
Local ready
Direct docking supported
|
|
E3L031491
BDB031491
|
BDBM628728
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3C[C@@H]4C[C@H]3CN4C)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H32Cl2N4O3 567.517000 |
PBBNOTCNGPJVQE-GPBNSJJESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628728
|
Local ready
Direct docking supported
|
|
E3L031492
BDB031492
|
US11236047, Example 171
C[S+]([O-])C1(CO[C@]2(c3ccc(Cl)cc3)c3c(F)cc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cn2)CC1
|
C28H27Cl2FN2O4S 577.505000 |
BMDCWINLUAOPGG-GOGSRFGOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628737; PubChem:CID135282711
|
Local ready
Direct docking supported
|
|
E3L031493
BDB031493
|
BDBM628759
COCC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1
|
C29H28Cl2FN3O5 588.463000 |
AIEAOHAGKSEEQE-ZBAATNBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628759
|
Local ready
Direct docking supported
|
|
E3L031494
BDB031494
|
BDBM628764
CN1CCN(CC(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cn2)[C@@]3(OCC2(O)CC2)c2ccc(Cl)cc2)CC1
|
C32H35Cl2FN4O4 629.560000 |
WEFUOIXZLXJHFW-BDJZEIKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628764
|
Local ready
Direct docking supported
|
|
E3L031495
BDB031495
|
BDBM628781
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(O)C3CCN(C(C)=O)CC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H30Cl2FN3O4 586.491000 |
LNMLPCBQBMWPBU-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628781; PubChem:CID135282617
|
Local ready
Direct docking supported
|
|
E3L031496
BDB031496
|
BDBM628789
COC[C@](C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C28H27Cl2FN2O5 561.437000 |
JTWNLIFKVVQASM-QLCOJLISSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628789
|
Local ready
Direct docking supported
|
|
E3L031497
BDB031497
|
BDBM628790
COC[C@@](C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C28H27Cl2FN2O5 561.437000 |
JTWNLIFKVVQASM-XDAJTCOGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628790; PubChem:CID169490062
|
Local ready
Direct docking supported
|
|
E3L031498
BDB031498
|
BDBM628816
CC1CC1(O)[C@@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(O)c3cnn(C)c3)cc2C(=O)N1Cc1ccc(C#N)cn1
|
C31H27ClFN5O3 572.040000 |
IKGIFWKNQLEOBP-KBEZNOJVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628816
|
Local ready
Direct docking supported
|
|
E3L031499
BDB031499
|
BDBM628826
Cn1cc(C(O)Cc2cc(F)c3c(c2)C(=O)N(Cc2cc(Cl)cc[n+]2[O-])C3(OCC2(C#N)CC2)c2ccc(Cl)cc2)cn1
|
C31H26Cl2FN5O4 622.484000 |
WWMCQXFLDHEBLB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628826
|
Local ready
Direct docking supported
|
|
E3L031500
BDB031500
|
US11236047, Example 409
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)c[n+]2[O-])[C@@]3(OCC2(O)CC2)c2ccc(Cl)cc2)cn1
|
C30H27Cl2FN4O5 613.473000 |
XFMUFTRUWONRPH-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628827; PubChem:CID137497969
|
Local ready
Direct docking supported
|