| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035201
BDB035201
|
US12172992, Example 12
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)CC4)cn3)ncn2)c(F)cc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C41H46FN11O4 775.890000 |
VCYKHFWTVADJIM-AREMUKBSSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708096; PubChem:CID169081330
|
Local ready
Direct docking supported
|
|
E3L035202
BDB035202
|
US12172992, Example 13
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C(C)C)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C44H53N11O4 799.981000 |
FJLQPZAPFKXILN-JQMWFGOGSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708097; PubChem:CID169081271
|
Local ready
Direct docking supported
|
|
E3L035203
BDB035203
|
US12172992, Example 14
C[C@@H](NC(=O)c1nc(C(C)(C)C)no1)c1ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)cc1Cl
|
C41H46ClN11O4 792.345000 |
DQWWVCQXTSHOSR-IZZNHLLZSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708098; PubChem:CID169081333
|
Local ready
Direct docking supported
|
|
E3L035204
BDB035204
|
US12172992, Example 15
COC[C@H]1CN(CCc2ccc(N3CCC(=O)NC3=O)cc2)CCN1c1ccc(Nc2cc(-c3ccc([C@@H](C)NC(=O)c4nc(C(C)(C)C)no4)c(C)c3)ncn2)nc1
|
C43H51N11O5 801.953000 |
HWIOHEPNEVRULC-LHXZUMEBSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708099; PubChem:CID169081308
|
Local ready
Direct docking supported
|
|
E3L035205
BDB035205
|
US12172992, Example 16
C[C@@H](NC(=O)c1nc(C(C)(C)C)no1)c1ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)cc1C(F)(F)F
|
C42H46F3N11O4 825.897000 |
FBCKBVQQCMIWBW-IZZNHLLZSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708100; PubChem:CID169081282
|
Local ready
Direct docking supported
|
|
E3L035206
BDB035206
|
US12172992, Example 17
C[C@@H](NC(=O)c1nc(C(C)(C)C)no1)c1ccc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cn3)ncn2)cc1F
|
C41H46FN11O4 775.890000 |
WCKXKIOIVQPJQO-IZZNHLLZSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708101; PubChem:CID169081268
|
Local ready
Direct docking supported
|
|
E3L035207
BDB035207
|
US12172992, Example 18
Cc1cc(-c2cc(Nc3ccc(N4CCN(CCc5ccc(N6CCC(=O)NC6=O)cc5)C[C@@H]4C)cc3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C43H50N10O4 770.939000 |
BGEYTGUDGVSOEH-URLMMPGGSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708102; PubChem:CID171663797
|
Local ready
Direct docking supported
|
|
E3L035208
BDB035208
|
US12172992, Example 19
Cc1cc(-c2cc(Nc3ccc(CCN4CCN(c5ccc(N6CCC(=O)NC6=O)cc5)CC4)cn3)ncn2)ccc1[C@@H](C)NC(=O)c1nc(C(C)(C)C)no1
|
C41H47N11O4 757.900000 |
CMSGLJCUFFEKTP-HHHXNRCGSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708103; PubChem:CID169205513
|
Local ready
Direct docking supported
|
|
E3L035209
BDB035209
|
BDBM708491
Cc1nc2cccc(C#CCCCCCCN3CCN(C)CC3)c2c(=O)n1C1CCC(=O)NC1=O
|
C27H35N5O3 477.609000 |
RKROHFOPAOBOOC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708491; PubChem:CID169093672
|
Local ready
Direct docking supported
|
|
E3L035210
BDB035210
|
BDBM708492
Cc1nc2cccc(NCCCCCCCNC34CC5CC(CC(C5)C3)C4)c2c(=O)n1C1CCC(=O)NC1=O
|
C31H43N5O3 533.717000 |
VRGSIZJFEYOJKC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708492; PubChem:CID169093832
|
Local ready
Direct docking supported
|
|
E3L035211
BDB035211
|
BDBM708493
Cc1nc2cccc(SCCCN3CCN(CCC45CC6CC(CC(C6)C4)C5)CC3)c2c(=O)n1C1CCC(=O)NC1=O
|
C33H45N5O3S 591.822000 |
AFGXZDCBACJZIF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708493; PubChem:CID169093675
|
Local ready
Direct docking supported
|
|
E3L035212
BDB035212
|
BDBM708494
Cc1nc2cccc(NCCCNC3C4CC5CC(C4)CC3C5)c2c(=O)n1C1CCC(=O)NC1=O
|
C27H35N5O3 477.609000 |
BQVFLLJKKFVPGU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708494; PubChem:CID169093869
|
Local ready
Direct docking supported
|
|
E3L035213
BDB035213
|
BDBM708495
Cc1nc2cccc(CCCCCNC34CC5CC(CC(C5)C3)C4)c2c(=O)n1C1CCC(=O)NC1=O
|
C29H38N4O3 490.648000 |
LXDFWZBTVDKQGK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708495; PubChem:CID169093667
|
Local ready
Direct docking supported
|
|
E3L035214
BDB035214
|
BDBM708496
Cc1nc2cccc(NCCCCCCNC34CC5CC(CC3C5)C4)c2c(=O)n1C1CCC(=O)NC1=O
|
C29H39N5O3 505.663000 |
QIVBYMZVLRKNGX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708496; PubChem:CID175664434
|
Local ready
Direct docking supported
|
|
E3L035215
BDB035215
|
BDBM708497
Cc1nc2cccc(CCCCCCCCNC34CC5CC(CC(C5)C3)C4)c2c(=O)n1C1CCC(=O)NC1=O
|
C32H44N4O3 532.729000 |
SFEDZLDUEXKKHE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708497; PubChem:CID169093864
|
Local ready
Direct docking supported
|
|
E3L035216
BDB035216
|
BDBM708498
Cc1nc2cccc(NCCCCCCCNC34CC5CC(CC3C5)C4)c2c(=O)n1C1CCC(=O)NC1=O
|
C30H41N5O3 519.690000 |
YJWDUFGYXFIAFE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708498; PubChem:CID175664435
|
Local ready
Direct docking supported
|
|
E3L035217
BDB035217
|
BDBM708499
Cc1nc2cccc(CCCCCCCCN3CCC(N4CCN(C)CC4)CC3)c2c(=O)n1C1CCC(=O)NC1=O
|
C32H48N6O3 564.775000 |
QCQYCSFTQBTAGA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708499; PubChem:CID169093866
|
Local ready
Direct docking supported
|
|
E3L035218
BDB035218
|
BDBM708500
Cc1nc2cccc(NCCCCCCCN3CCCN(C)CC3)c2c(=O)n1C1CCC(=O)NC1=O
|
C27H40N6O3 496.656000 |
IPEJHFSMGXDMIA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708500; PubChem:CID169093854
|
Local ready
Direct docking supported
|
|
E3L035219
BDB035219
|
BDBM708501
Cc1nc2cccc(CCCCCCCCN3CC4CC(C3)O4)c2c(=O)n1C1CCC(=O)NC1=O
|
C27H36N4O4 480.609000 |
ZLTIXAIJPFSJLM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708501; PubChem:CID169093784
|
Local ready
Direct docking supported
|
|
E3L035220
BDB035220
|
BDBM708502
Cc1nc2cccc(NCCCCCCCO)c2c(=O)n1C1CCC(=O)NC1=O
|
C21H28N4O4 400.479000 |
PWLHTQLSYWAPMZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM708502; PubChem:CID169093638
|
Local ready
Direct docking supported
|