| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035261
BDB035261
|
BDBM708601
O=S(=O)(Nc1ccc(Cl)c2c(Cl)c[nH]c12)c1ccc2ccccc2c1F
|
C18H11Cl2FN2O2S 409.269000 |
QCUISRXOXPZTPA-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708601; PubChem:CID168199833
|
Local ready
Direct docking supported
|
|
E3L035262
BDB035262
|
BDBM708602
O=S(=O)(Nc1ccc(Cl)c2c(Cl)c[nH]c12)c1ccc2c(c1)CC[C@@H](C(F)F)O2
|
C18H14Cl2F2N2O3S 447.290000 |
UMVXEKUHGVXWLG-HNNXBMFYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708602; PubChem:CID168199926
|
Local ready
Direct docking supported
|
|
E3L035263
BDB035263
|
BDBM708603
O=C1OCCc2ccc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)cc21
|
C17H12Cl2N2O4S 411.266000 |
VKQYYZGUHCIUCG-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708603; PubChem:CID175664444
|
Local ready
Direct docking supported
|
|
E3L035264
BDB035264
|
BDBM708604
O=C1NCCc2ccc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)cc21
|
C17H13Cl2N3O3S 410.282000 |
JBQOAJDNHRPSRC-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708604; PubChem:CID168199962
|
Local ready
Direct docking supported
|
|
E3L035265
BDB035265
|
BDBM708605
O=C1CCc2cc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)c(F)cc2N1
|
C17H12Cl2FN3O3S 428.272000 |
PBVXOBPGXFDQQO-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708605; PubChem:CID175664445
|
Local ready
Direct docking supported
|
|
E3L035266
BDB035266
|
BDBM708606
CC1(C)CC(=O)Nc2ccc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)cc21
|
C19H17Cl2N3O3S 438.336000 |
VZFOEULATCOWBT-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708606; PubChem:CID168199920
|
Local ready
Direct docking supported
|
|
E3L035267
BDB035267
|
BDBM708607
O=c1ccc2cc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)ccc2[nH]1
|
C17H11Cl2N3O3S 408.266000 |
KLLBALYOHWOWHS-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708607; PubChem:CID168199969
|
Local ready
Direct docking supported
|
|
E3L035268
BDB035268
|
BDBM708608
O=S(=O)(Nc1ccc(Cl)c2c(Cl)c[nH]c12)c1cc(Br)c2c(c1)OCCO2
|
C16H11BrCl2N2O4S 478.151000 |
XZNDXVSPRSSJCL-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708608; PubChem:CID168199894
|
Local ready
Direct docking supported
|
|
E3L035269
BDB035269
|
BDBM708609
CN1Cc2cc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)ccc2OC1=O
|
C17H13Cl2N3O4S 426.281000 |
TZXLGGPBMNZNOP-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708609; PubChem:CID168199837
|
Local ready
Direct docking supported
|
|
E3L035270
BDB035270
|
BDBM708610
O=C1NCc2cc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)ccc2O1
|
C16H11Cl2N3O4S 412.254000 |
SUPJJCPQGLOUTP-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708610; PubChem:CID168199949
|
Local ready
Direct docking supported
|
|
E3L035271
BDB035271
|
BDBM708611
O=C1COc2cc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)cnc2N1
|
C15H10Cl2N4O4S 413.242000 |
GLCWFMIMJYKZTN-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708611; PubChem:CID175664446
|
Local ready
Direct docking supported
|
|
E3L035272
BDB035272
|
BDBM708612
CC(C)(C)OC(=O)N1CCCc2cc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)ccc2C1
|
C23H25Cl2N3O4S 510.443000 |
NUCJQZDGSRBDKA-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708612; PubChem:CID168199963
|
Local ready
Direct docking supported
|
|
E3L035273
BDB035273
|
BDBM708613
O=C1NCCOc2ccc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)cc21
|
C17H13Cl2N3O4S 426.281000 |
YSEMYMJSWGPWMP-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708613; PubChem:CID175664447
|
Local ready
Direct docking supported
|
|
E3L035274
BDB035274
|
BDBM708614
O=C1CCSc2ccc(S(=O)(=O)Nc3ccc(Cl)c4c(Cl)c[nH]c34)cc2N1
|
C17H13Cl2N3O3S2 442.349000 |
ZXBWZAIDTPHYHJ-UHFFFAOYSA-N | Q66K64 | DDB1- and CUL4-associated factor 15 |
BindingDB, PubChem
BindingDB:BDBM708614; PubChem:CID175664448
|
Local ready
Direct docking supported
|
|
E3L035275
BDB035275
|
US20240425497, Example 1
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N(C)C)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C34H38FN5O2 567.709000 |
PSMQINHMVZABFS-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708615; PubChem:CID175664449
|
Local ready
Direct docking supported
|
|
E3L035276
BDB035276
|
US20240425497, Example 2
CCOCCNC(=O)c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C3CC3)c3cc(CN4CCC[C@H](C)C4)[nH]c3c2=O)c1
|
C36H42FN5O3 611.762000 |
YYZHEVNJPCRBHE-QFIPXVFZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708617; PubChem:CID175664451
|
Local ready
Direct docking supported
|
|
E3L035277
BDB035277
|
US20240425497, Example 3
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CCOCC5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C36H40FN5O3 609.746000 |
OHQAXFRAUOMKRD-QFIPXVFZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708619; PubChem:CID175664453
|
Local ready
Direct docking supported
|
|
E3L035278
BDB035278
|
US20240425497, Example 4
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CCCC5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C36H40FN5O2 593.747000 |
HQVZRXPEHCFSAJ-QFIPXVFZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708620; PubChem:CID175664454
|
Local ready
Direct docking supported
|
|
E3L035279
BDB035279
|
US20240425497, Example 5
CCN(CC)C(=O)c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C3CC3)c3cc(CN4CCC[C@H](C)C4)[nH]c3c2=O)c1
|
C36H42FN5O2 595.763000 |
FAUVKKSOAQHAMB-QFIPXVFZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708675; PubChem:CID175664507
|
Local ready
Direct docking supported
|
|
E3L035280
BDB035280
|
US20240425497, Example 6
CNC(=O)c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C3CC3)c3cc(CN4CCC[C@H](C)C4)[nH]c3c2=O)c1
|
C33H36FN5O2 553.682000 |
IYWXIELCPPIKSI-IBGZPJMESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708678; PubChem:CID175664510
|
Local ready
Direct docking supported
|