| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035521
BDB035521
|
BDBM710813
C[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)c1nncn1C
|
C26H28F3N5O 483.538000 |
CEHFSPNJELKNGN-INIZCTEOSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710813; PubChem:CID168262647
|
Local ready
Direct docking supported
|
|
E3L035522
BDB035522
|
BDBM710814
CO[C@H]1C[C@@](c2cccc(N3Cc4c(cc(CN5CCN(C)C[C@@H]5C(C)C)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H39F3N6O2 596.698000 |
ATFYKJXJVMDYAJ-HAFIXEQPSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710814
|
Local ready
Direct docking supported
|
|
E3L035523
BDB035523
|
BDBM710815
C[C@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc(C3(c4nncn4C)CC(F)(F)C3)c1)C2=O
|
C29H30F5N5O 559.583000 |
YAXIXGGRDHAOJL-KRWDZBQOSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710815; PubChem:CID168262505
|
Local ready
Direct docking supported
|
|
E3L035524
BDB035524
|
BDBM710816
C[C@@H](NC1(C)CCC1)c1cc2c(c(C(F)(F)F)c1)CN(c1cccc(C3(c4nncn4C)CC(F)(F)C3)c1)C2=O
|
C29H30F5N5O 559.583000 |
YAXIXGGRDHAOJL-QGZVFWFLSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710816; PubChem:CID168262785
|
Local ready
Direct docking supported
|
|
E3L035525
BDB035525
|
BDBM710817
CO[C@H]1C[C@@](c2cccc(N3Cc4c(cc([C@@H](C)NC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
GFHVYXFCSPKJGR-XZNQMBMJSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710817
|
Local ready
Direct docking supported
|
|
E3L035526
BDB035526
|
BDBM710818
CO[C@H]1C[C@@](c2cccc(N3Cc4c(cc([C@H](C)NC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
GFHVYXFCSPKJGR-RHJMBEETSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710818
|
Local ready
Direct docking supported
|
|
E3L035527
BDB035527
|
BDBM710819
Cn1cnnc1[C@]1(c2cc(NC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](C)C1
|
C34H41F3N6O 606.737000 |
PMARLWUYKMTAJS-MNNYYHTESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710819
|
Local ready
Direct docking supported
|
|
E3L035528
BDB035528
|
BDBM710820
CCO[C@H]1C[C@@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
LQIXQCXHUWUIFK-JGCHJSNTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710820
|
Local ready
Direct docking supported
|
|
E3L035529
BDB035529
|
BDBM710821
CCO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
LQIXQCXHUWUIFK-FXBOJIBUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710821
|
Local ready
Direct docking supported
|
|
E3L035530
BDB035530
|
BDBM710822
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc(CN5CCN(C)C[C@@H]5C(C)C)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H39F3N6O2 596.698000 |
ATFYKJXJVMDYAJ-HVOSOHGQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710822
|
Local ready
Direct docking supported
|
|
E3L035531
BDB035531
|
BDBM710823
CCOc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](C)C2)c1
|
C31H36F3N5O2 567.656000 |
GTCCTXMDEHLUPB-ZOXYEEGJSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710823
|
Local ready
Direct docking supported
|
|
E3L035532
BDB035532
|
BDBM710824
CCOc1cc(C2(c3nncn3C)CC(F)(F)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C29H31F5N6O2 590.597000 |
COGZHOHLOCYJAR-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710824; PubChem:CID168262862
|
Local ready
Direct docking supported
|
|
E3L035533
BDB035533
|
BDBM710825
Cn1cnnc1[C@]1(c2cc(NC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](C)C1
|
C34H41F3N6O 606.737000 |
PMARLWUYKMTAJS-RIMNUOPMSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710825
|
Local ready
Direct docking supported
|
|
E3L035534
BDB035534
|
BDBM710826
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc([C@@H](C)NC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
GFHVYXFCSPKJGR-FJLHWALTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710826
|
Local ready
Direct docking supported
|
|
E3L035535
BDB035535
|
BDBM710827
CO[C@H]1C[C@](c2cccc(N3Cc4c(cc([C@H](C)NC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
GFHVYXFCSPKJGR-RIRMVKJXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710827
|
Local ready
Direct docking supported
|
|
E3L035536
BDB035536
|
BDBM710828
Cn1cnnc1[C@]1(c2cc(OC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@H](C)C1
|
C34H40F3N5O2 607.721000 |
ZODREUNJEPMICB-MNNYYHTESA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710828
|
Local ready
Direct docking supported
|
|
E3L035537
BDB035537
|
BDBM710829
Cn1cnnc1C1(c2cc(NCCC#N)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC2(COC2)C1
|
C32H35F3N8O2 620.680000 |
LVUXAWRXYVQYCL-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710829
|
Local ready
Direct docking supported
|
|
E3L035538
BDB035538
|
BDBM710830
Cn1cnnc1C1(c2cc(NC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC2(COC2)C1
|
C34H40F3N7O2 635.735000 |
NESWXWLBMJYMDN-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710830
|
Local ready
Direct docking supported
|
|
E3L035539
BDB035539
|
BDBM710831
CCOc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](C)C2)c1
|
C31H36F3N5O2 567.656000 |
GTCCTXMDEHLUPB-JYRGKNSPSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710831
|
Local ready
Direct docking supported
|
|
E3L035540
BDB035540
|
BDBM710832
CO[C@H]1C[C@@](c2cccc(N3Cc4c(cccc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C23H21F3N4O2 442.441000 |
HWFJEYYGSBPHKJ-MIRVZWSXSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710832
|
Local ready
Direct docking supported
|