| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035561
BDB035561
|
BDBM710853
CO[C@H]1C[C@](c2cc(NC3CCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H39F3N6O2 608.709000 |
ZJABPXCKZJSAKI-MWZCXBCDSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710853
|
Local ready
Direct docking supported
|
|
E3L035562
BDB035562
|
BDBM710854
CO[C@H]1C[C@](c2cc(OC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C34H40F3N5O3 623.720000 |
UQDLRCLRFNHSAU-HGIILVDHSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710854
|
Local ready
Direct docking supported
|
|
E3L035563
BDB035563
|
BDBM710855
C=C[C@@H](C)Oc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C33H38F3N5O3 609.693000 |
CDXAKGFOHNPQOB-SQVASEQXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710855
|
Local ready
Direct docking supported
|
|
E3L035564
BDB035564
|
BDBM710856
CO[C@H]1C[C@](c2cc(NC3CC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H37F3N6O2 594.682000 |
JSVAQNCBNKUVIB-ZMZPAPJQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710856
|
Local ready
Direct docking supported
|
|
E3L035565
BDB035565
|
BDBM710857
CO[C@H]1C[C@](c2cc(NC(C)C)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H39F3N6O2 596.698000 |
OUQCWTKXHVIBQY-ZMZPAPJQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710857
|
Local ready
Direct docking supported
|
|
E3L035566
BDB035566
|
BDBM710858
CO[C@H]1C[C@](c2cc(NCCC#N)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H36F3N7O2 607.681000 |
ORCBPUXWRVQPOS-ZMZPAPJQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710858
|
Local ready
Direct docking supported
|
|
E3L035567
BDB035567
|
BDBM710859
CO[C@H]1C[C@@](c2cc(NC3CCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H39F3N6O2 608.709000 |
ZJABPXCKZJSAKI-HFMWNBCUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710859
|
Local ready
Direct docking supported
|
|
E3L035568
BDB035568
|
BDBM710860
CO[C@H]1C[C@@](c2cc(NC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C34H41F3N6O2 622.736000 |
XYSMLTDOEYEKPK-MJOFNPIESA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710860
|
Local ready
Direct docking supported
|
|
E3L035569
BDB035569
|
BDBM710861
C=C[C@@H](C)Nc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C33H39F3N6O2 608.709000 |
KWEMJZWHNJCGCV-WZTPMAIESA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710861
|
Local ready
Direct docking supported
|
|
E3L035570
BDB035570
|
BDBM710862
C=C[C@H](C)Nc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C33H39F3N6O2 608.709000 |
KWEMJZWHNJCGCV-UWIRTIHQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710862
|
Local ready
Direct docking supported
|
|
E3L035571
BDB035571
|
BDBM710863
CO[C@H]1C[C@](c2cc(N[C@H](C)CC#N)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H38F3N7O2 621.708000 |
WHOHIBXOMRSQNS-WZTPMAIESA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710863
|
Local ready
Direct docking supported
|
|
E3L035572
BDB035572
|
BDBM710864
CC(C)O[C@H]1C[C@@](c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C31H36F3N5O2 567.656000 |
XNSWVOGEJVAEKL-IKFUVLSHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710864
|
Local ready
Direct docking supported
|
|
E3L035573
BDB035573
|
BDBM710865
CO[C@H]1C[C@@](c2cc(NC(C)C)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H39F3N6O2 596.698000 |
OUQCWTKXHVIBQY-YKAHFMHQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710865
|
Local ready
Direct docking supported
|
|
E3L035574
BDB035574
|
BDBM710866
CO[C@H]1C[C@@](c2cc(NCCC#N)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H36F3N7O2 607.681000 |
ORCBPUXWRVQPOS-YKAHFMHQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710866
|
Local ready
Direct docking supported
|
|
E3L035575
BDB035575
|
BDBM710867
CO[C@H]1C[C@](c2cc(N[C@@H](C)CC#N)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H38F3N7O2 621.708000 |
WHOHIBXOMRSQNS-UWIRTIHQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710867
|
Local ready
Direct docking supported
|
|
E3L035576
BDB035576
|
BDBM710868
CO[C@H]1C[C@](c2cc(C3CCC3)cc(N3Cc4c(ccc(CCNC5(C)CCC5)c4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C34H40F3N5O2 607.721000 |
VIWNREIXEHEUNK-HGIILVDHSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710868
|
Local ready
Direct docking supported
|
|
E3L035577
BDB035577
|
BDBM710869
CCNc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C31H37F3N6O2 582.671000 |
RIURYJBLZUYQIW-IKFUVLSHSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710869
|
Local ready
Direct docking supported
|
|
E3L035578
BDB035578
|
BDBM710870
CO[C@H]1C[C@@](c2cc(N[C@H](C)CC#N)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H38F3N7O2 621.708000 |
WHOHIBXOMRSQNS-SQVASEQXSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710870
|
Local ready
Direct docking supported
|
|
E3L035579
BDB035579
|
BDBM710871
COC1CC2(C1)CC(c1cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c1)(c1nncn1C)C2
|
C32H36F3N5O2 579.667000 |
JAZNXJCUDFXHRC-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710871; PubChem:CID168262741
|
Local ready
Direct docking supported
|
|
E3L035580
BDB035580
|
BDBM710872
CO[C@H]1C[C@](c2cc(C)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
WZUGJNYAYDDNBV-FXBOJIBUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710872
|
Local ready
Direct docking supported
|