| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035581
BDB035581
|
BDBM710873
CO[C@H]1C[C@@](c2cc(NC3CC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H37F3N6O2 594.682000 |
JSVAQNCBNKUVIB-YKAHFMHQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710873
|
Local ready
Direct docking supported
|
|
E3L035582
BDB035582
|
BDBM710874
C=CCNc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C32H37F3N6O2 594.682000 |
HFYHVKQQIOBAEU-ZMZPAPJQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710874
|
Local ready
Direct docking supported
|
|
E3L035583
BDB035583
|
BDBM710875
CO[C@H]1C[C@@](c2cc(N[C@@H](C)CC#N)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C33H38F3N7O2 621.708000 |
WHOHIBXOMRSQNS-MSTDZMJESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710875
|
Local ready
Direct docking supported
|
|
E3L035584
BDB035584
|
BDBM710876
CO[C@H]1C[C@](c2cc(NC3COC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H37F3N6O3 610.681000 |
ONQZVCBYRFYYFU-ZMZPAPJQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710876
|
Local ready
Direct docking supported
|
|
E3L035585
BDB035585
|
BDBM710877
CCc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C31H36F3N5O2 567.656000 |
MFIFUEVAYDVUNR-IKFUVLSHSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710877
|
Local ready
Direct docking supported
|
|
E3L035586
BDB035586
|
BDBM710878
CCc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C31H36F3N5O2 567.656000 |
MFIFUEVAYDVUNR-HWSBAZIVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710878
|
Local ready
Direct docking supported
|
|
E3L035587
BDB035587
|
BDBM710879
CO[C@H]1C[C@@](c2cc(C)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C30H34F3N5O2 553.629000 |
WZUGJNYAYDDNBV-JGCHJSNTSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710879
|
Local ready
Direct docking supported
|
|
E3L035588
BDB035588
|
BDBM710880
CNc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C30H35F3N6O2 568.644000 |
HXLADLNGYXZCMU-JGCHJSNTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710880
|
Local ready
Direct docking supported
|
|
E3L035589
BDB035589
|
BDBM710881
CNc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C30H35F3N6O2 568.644000 |
HXLADLNGYXZCMU-FXBOJIBUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710881
|
Local ready
Direct docking supported
|
|
E3L035590
BDB035590
|
BDBM710882
C=CCNc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C32H37F3N6O2 594.682000 |
HFYHVKQQIOBAEU-YKAHFMHQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710882
|
Local ready
Direct docking supported
|
|
E3L035591
BDB035591
|
BDBM710883
CO[C@H]1C[C@@](c2cc(OC3COC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H36F3N5O4 611.665000 |
YMHSMYQKKBITTG-FESQKGCISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710883
|
Local ready
Direct docking supported
|
|
E3L035592
BDB035592
|
BDBM710884
CO[C@H]1C[C@](c2cc(OC3COC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H36F3N5O4 611.665000 |
YMHSMYQKKBITTG-CSKXWMIVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710884
|
Local ready
Direct docking supported
|
|
E3L035593
BDB035593
|
BDBM710885
CO[C@H]1C[C@@](c2cc(NC3COC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H37F3N6O3 610.681000 |
ONQZVCBYRFYYFU-YKAHFMHQSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710885
|
Local ready
Direct docking supported
|
|
E3L035594
BDB035594
|
BDBM710886
Cn1cnnc1[C@@H](CC1COC1)c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C29H32F3N5O2 539.602000 |
DSDJIRIDXIBOFP-QFIPXVFZSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710886; PubChem:CID168835259
|
Local ready
Direct docking supported
|
|
E3L035595
BDB035595
|
BDBM710887
Cn1cnnc1[C@H](CC1COC1)c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C29H32F3N5O2 539.602000 |
DSDJIRIDXIBOFP-JOCHJYFZSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710887; PubChem:CID168262575
|
Local ready
Direct docking supported
|
|
E3L035596
BDB035596
|
BDBM710888
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(Cl)cc(CNC5(C)CCC5)cc4C3=O)c2)C[C@H](F)C1
|
C27H29ClFN5O 494.014000 |
WRDBAVILVSZTIZ-JKCYLYBBSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710888
|
Local ready
Direct docking supported
|
|
E3L035597
BDB035597
|
BDBM710889
Cn1cnnc1[C@]1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)F)C3=O)c2)C[C@H](F)C1
|
C28H30F3N5O 509.576000 |
WSJUWJIMIXGBMP-GCSLNTQSSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710889
|
Local ready
Direct docking supported
|
|
E3L035598
BDB035598
|
BDBM710890
Cn1cnnc1[C@@H](CC1CCCC1)c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C31H36F3N5O 551.657000 |
ZEUMEZFBWOSCJL-DEOSSOPVSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710890; PubChem:CID168263087
|
Local ready
Direct docking supported
|
|
E3L035599
BDB035599
|
BDBM710891
Cn1cnnc1[C@H](CC1CCCC1)c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1
|
C31H36F3N5O 551.657000 |
ZEUMEZFBWOSCJL-XMMPIXPASA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710891; PubChem:CID169725548
|
Local ready
Direct docking supported
|
|
E3L035600
BDB035600
|
BDBM710892
Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CCCCC1
|
C31H36F3N5O 551.657000 |
WHAGYOFNTCYTHQ-HHHXNRCGSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710892; PubChem:CID168263078
|
Local ready
Direct docking supported
|