| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035541
BDB035541
|
BDBM710833
Cn1cnnc1C1(c2cccc(N3Cc4c(cccc4C(F)(F)F)C3=O)c2)CC2(COC2)C1
|
C24H21F3N4O2 454.452000 |
UIODFAKPJLKMQL-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710833; PubChem:CID168835221
|
Local ready
Direct docking supported
|
|
E3L035542
BDB035542
|
BDBM710834
C[C@H](CC#N)Nc1cc(C2(c3nncn3C)CC3(COC3)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C33H37F3N8O2 634.707000 |
ZCHQPXGYEGSHHI-HXUWFJFHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710834
|
Local ready
Direct docking supported
|
|
E3L035543
BDB035543
|
BDBM710835
Cn1cnnc1C1(c2cc(OC3CCCC3)nc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC2(COC2)C1
|
C34H39F3N6O3 636.719000 |
HJPRIMCYDHVCTJ-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710835
|
Local ready
Direct docking supported
|
|
E3L035544
BDB035544
|
BDBM710836
C[C@@H](CC#N)Nc1cc(C2(c3nncn3C)CC3(COC3)C2)cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)n1
|
C33H37F3N8O2 634.707000 |
ZCHQPXGYEGSHHI-FQEVSTJZSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710836
|
Local ready
Direct docking supported
|
|
E3L035545
BDB035545
|
BDBM710837
Cn1cnnc1[C@]1(c2cc(OC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)C[C@@H](C)C1
|
C34H40F3N5O2 607.721000 |
ZODREUNJEPMICB-RIMNUOPMSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710837
|
Local ready
Direct docking supported
|
|
E3L035546
BDB035546
|
BDBM710838
CO[C@H]1C[C@](c2cccc(N3Cc4c(cccc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C23H21F3N4O2 442.441000 |
HWFJEYYGSBPHKJ-CIEDQVTBSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710838
|
Local ready
Direct docking supported
|
|
E3L035547
BDB035547
|
BDBM710839
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)F)C3=O)c2)CC2(COC2)C1
|
C30H33F2N5O2 533.623000 |
ZCWNSFCDGJTSOG-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM710839; PubChem:CID168262856
|
Local ready
Direct docking supported
|
|
E3L035548
BDB035548
|
BDBM710840
CC(C)[C@H]1CN(C)CCN1Cc1cc2c(c(C(F)F)c1)CN(c1cccc(C3(c4nncn4C)CC4(COC4)C3)c1)C2=O
|
C33H40F2N6O2 590.719000 |
SNINXEPVBOIZBX-MUUNZHRXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710840
|
Local ready
Direct docking supported
|
|
E3L035549
BDB035549
|
BDBM710841
Cn1cnnc1C1(c2cccc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC2(CN(C3COC3)C2)C1
|
C33H37F3N6O2 606.693000 |
AIOZKRSZSKUXNC-UHFFFAOYSA-N | Q13191 | Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710841
|
Local ready
Direct docking supported
|
|
E3L035550
BDB035550
|
BDBM710842
COc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C30H34F3N5O3 569.628000 |
ZGNQSVGROPGZJH-JGCHJSNTSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710842
|
Local ready
Direct docking supported
|
|
E3L035551
BDB035551
|
BDBM710843
COc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C30H34F3N5O3 569.628000 |
ZGNQSVGROPGZJH-FXBOJIBUSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710843
|
Local ready
Direct docking supported
|
|
E3L035552
BDB035552
|
BDBM710844
CCOc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C31H36F3N5O3 583.655000 |
PISGPHDAGMGMKC-HWSBAZIVSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710844
|
Local ready
Direct docking supported
|
|
E3L035553
BDB035553
|
BDBM710845
CCOc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C31H36F3N5O3 583.655000 |
PISGPHDAGMGMKC-IKFUVLSHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710845
|
Local ready
Direct docking supported
|
|
E3L035554
BDB035554
|
BDBM710846
CC(C)[C@H]1CN(C)CCN1Cc1cc(Cl)c2c(c1)C(=O)N(c1cccc(C3(c4nncn4C)CC4(COC4)C3)c1)C2
|
C32H39ClN6O2 575.157000 |
DWUWREPGQDQGAG-MUUNZHRXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB, PubChem
BindingDB:BDBM710846; PubChem:CID168263119
|
Local ready
Direct docking supported
|
|
E3L035555
BDB035555
|
BDBM710847
C=CCOc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@@H](OC)C2)c1
|
C32H36F3N5O3 595.666000 |
QYBXDVKBBXOQPH-YKAHFMHQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710847
|
Local ready
Direct docking supported
|
|
E3L035556
BDB035556
|
BDBM710848
CO[C@H]1C[C@@](c2cc(OC(C)C)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H38F3N5O3 597.682000 |
RASXVOITJOZVAZ-YKAHFMHQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710848
|
Local ready
Direct docking supported
|
|
E3L035557
BDB035557
|
BDBM710849
CO[C@H]1C[C@](c2cc(OC(C)C)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C32H38F3N5O3 597.682000 |
RASXVOITJOZVAZ-ZMZPAPJQSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710849
|
Local ready
Direct docking supported
|
|
E3L035558
BDB035558
|
BDBM710850
CO[C@H]1C[C@@](c2cc(OC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C34H40F3N5O3 623.720000 |
UQDLRCLRFNHSAU-MJOFNPIESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B, Tyrosine-protein kinase Lck |
BindingDB
BindingDB:BDBM710850
|
Local ready
Direct docking supported
|
|
E3L035559
BDB035559
|
BDBM710851
CO[C@H]1C[C@](c2cc(NC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C34H41F3N6O2 622.736000 |
XYSMLTDOEYEKPK-HGIILVDHSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710851
|
Local ready
Direct docking supported
|
|
E3L035560
BDB035560
|
BDBM710852
CCNc1cc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)cc([C@]2(c3nncn3C)C[C@H](OC)C2)c1
|
C31H37F3N6O2 582.671000 |
RIURYJBLZUYQIW-HWSBAZIVSA-N | Q13191 | Tyrosine-protein kinase Lck, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM710852
|
Local ready
Direct docking supported
|