| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L036061
BDB036061
|
US20250073340, Example 25
COc1cc(C(=O)N2CCC[C@@H](CC#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C52H53Cl2FN6O6 947.936000 |
BZUIBNLKEGFPOY-JALZAXBESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725178; PubChem:CID164591756
|
Local ready
Direct docking supported
|
|
E3L036062
BDB036062
|
US20250073340, Example 26
COc1cc(N2CCC([C@@H]3C[C@H]3C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)CC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H55Cl2FN6O5 945.964000 |
MTJRYKKDHIGCTE-DSLJZEAASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725179; PubChem:CID164591760
|
Local ready
Direct docking supported
|
|
E3L036063
BDB036063
|
US20250073340, Example 27
COc1cc(N2CCC([C@H]3C[C@@H]3C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)CC2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H55Cl2FN6O5 945.964000 |
MTJRYKKDHIGCTE-CXVSLVQASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725180; PubChem:CID164592050
|
Local ready
Direct docking supported
|
|
E3L036064
BDB036064
|
US20250073340, Example 28
COc1cc(N2CCC[C@H](C#Cc3cccc4c3CN([C@H]3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C50H51Cl2FN6O5 905.899000 |
FIWNKXFTVUEKIU-WVLVJXLASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725181; PubChem:CID164592042
|
Local ready
Direct docking supported
|
|
E3L036065
BDB036065
|
US20250073340, Example 29
COc1cc(N2CCC[C@H](C#Cc3cccc4c3CN([C@@H]3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C50H51Cl2FN6O5 905.899000 |
FIWNKXFTVUEKIU-BQRYPEBXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725182; PubChem:CID164591957
|
Local ready
Direct docking supported
|
|
E3L036066
BDB036066
|
US20250073340, Example 30
COc1cc(N2CCC[C@@H](C#Cc3cccc4c3CN([C@H]3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C50H51Cl2FN6O5 905.899000 |
FIWNKXFTVUEKIU-HZHHMLPXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725183; PubChem:CID164591790
|
Local ready
Direct docking supported
|
|
E3L036067
BDB036067
|
US20250073340, Example 31
COc1cc(N2CCC[C@@H](C#Cc3cccc4c3CN([C@@H]3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C50H51Cl2FN6O5 905.899000 |
FIWNKXFTVUEKIU-QGPPMENASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725184; PubChem:CID164591887
|
Local ready
Direct docking supported
|
|
E3L036068
BDB036068
|
US20250073340, Example 32
COc1cc(C(=O)N[C@H]2CCC[C@@H](C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C52H53Cl2FN6O6 947.936000 |
WDDAMBWSYNNFML-HSZWLBHHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725185; PubChem:CID164591782
|
Local ready
Direct docking supported
|
|
E3L036069
BDB036069
|
US20250073340, Example 33
COc1cc(C(=O)N[C@@H]2CCC[C@H](C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C52H53Cl2FN6O6 947.936000 |
WDDAMBWSYNNFML-HVSALXPMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725186; PubChem:CID164592081
|
Local ready
Direct docking supported
|
|
E3L036070
BDB036070
|
US20250073340, Example 34
COc1cc(C(=O)N[C@@H]2CCC[C@@H](C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C52H53Cl2FN6O6 947.936000 |
WDDAMBWSYNNFML-OOEVOJHYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725187; PubChem:CID164591785
|
Local ready
Direct docking supported
|
|
E3L036071
BDB036071
|
US20250073340, Example 35
COc1cc(C(=O)N[C@H]2CCC[C@H](C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C52H53Cl2FN6O6 947.936000 |
WDDAMBWSYNNFML-PZFCOGBCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725188; PubChem:CID164591890
|
Local ready
Direct docking supported
|
|
E3L036072
BDB036072
|
US20250073340, Example 36
COc1cc(C(=O)N2CCCC[C@@H]2CCC#Cc2cccc3c2CN([C@@H]2CCC(=O)NC2=O)C3=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H55Cl2FN6O6 961.963000 |
IXYOOVPYBMKDJC-ZANOWXKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725189; PubChem:CID164591952
|
Local ready
Direct docking supported
|
|
E3L036073
BDB036073
|
US20250073340, Example 37
COc1cc(C(=O)N2CCCC[C@@H]2CCC#Cc2cccc3c2CN([C@H]2CCC(=O)NC2=O)C3=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H55Cl2FN6O6 961.963000 |
IXYOOVPYBMKDJC-WYEFBMHZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725190; PubChem:CID164591781
|
Local ready
Direct docking supported
|
|
E3L036074
BDB036074
|
US20250073340, Example 38
COc1cc(C(=O)N2CCCC[C@H]2CCC#Cc2cccc3c2CN([C@@H]2CCC(=O)NC2=O)C3=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H55Cl2FN6O6 961.963000 |
IXYOOVPYBMKDJC-NJCIWUJVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725191; PubChem:CID164592135
|
Local ready
Direct docking supported
|
|
E3L036075
BDB036075
|
US20250073340, Example 39
COc1cc(C(=O)N2CCCC[C@H]2CCC#Cc2cccc3c2CN([C@H]2CCC(=O)NC2=O)C3=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H55Cl2FN6O6 961.963000 |
IXYOOVPYBMKDJC-VIRNSURXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725192; PubChem:CID164591827
|
Local ready
Direct docking supported
|
|
E3L036076
BDB036076
|
US20250073340, Example 42
COc1cc(C(=O)N2CCC3(CC2)CC(C#Cc2cccc4c2CN(C2CCC(=O)NC2=O)C4=O)C3)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C54H55Cl2FN6O6 973.974000 |
PSDVCWAVZUVVAE-SOHRZNMCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725193; PubChem:CID164592000
|
Local ready
Direct docking supported
|
|
E3L036077
BDB036077
|
US20250073340, Example 43
COc1cc(C(=O)N2CCC3(CC2)C[C@H]3C#Cc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H53Cl2FN6O6 959.947000 |
OAFXZDOTHLLNQB-FKQIRFKFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725194; PubChem:CID164592072
|
Local ready
Direct docking supported
|
|
E3L036078
BDB036078
|
US20250073340, Example 44
COc1cc(C(=O)N2CCC3(CC2)C[C@@H]3C#Cc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C53H53Cl2FN6O6 959.947000 |
OAFXZDOTHLLNQB-JLIFDDDZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725195; PubChem:CID164591910
|
Local ready
Direct docking supported
|
|
E3L036079
BDB036079
|
US20250073340, Example 48
COc1cc(C(=O)N2CC[C@H](C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C50H49Cl2FN6O6 919.882000 |
OKEWLZLGSGEXPQ-QPJXBYKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725196; PubChem:CID164592165
|
Local ready
Direct docking supported
|
|
E3L036080
BDB036080
|
US20250073340, Example 49
COc1cc(C(=O)N2CC[C@@H](C#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C50H49Cl2FN6O6 919.882000 |
OKEWLZLGSGEXPQ-JFTJSALISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM725197; PubChem:CID164591806
|
Local ready
Direct docking supported
|