| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L040641
BDB040641
|
BDBM761446
[2H]C1([2H])NC([2H])([2H])C([2H])([2H])N(c2cc3c(cc2F)C(=O)N(C2CCC(=O)NC2=O)C3=O)C1([2H])[2H]
|
C17H17FN4O4 368.393814 |
YNGDWIBEYDEYGU-SQUIKQQTSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM761446; PubChem:CID172209952
|
Local ready
Direct docking supported
|
|
E3L040642
BDB040642
|
BDBM761447
O=C1CCC(N2C(=O)c3ccc(N4CC5CCC4CN5)cc3C2=O)C(=O)N1
|
C19H20N4O4 368.393000 |
UKPZIBLMTKJJJV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM761447; PubChem:CID165946818
|
Local ready
Direct docking supported
|
|
E3L040643
BDB040643
|
BDBM762511
O=c1c2c(Nc3ccc(I)cc3F)cncc2ccn1C[C@@H](O)CO
|
C17H15FIN3O3 455.227000 |
IDEWSJRLCBJTLX-GFCCVEGCSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762511; PubChem:CID147895382
|
Local ready
Direct docking supported
|
|
E3L040644
BDB040644
|
BDBM762512
O=c1c2c(Nc3ccc(I)cc3F)cncc2ccn1C[C@H](O)CO
|
C17H15FIN3O3 455.227000 |
IDEWSJRLCBJTLX-LBPRGKRZSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762512; PubChem:CID147895383
|
Local ready
Direct docking supported
|
|
E3L040645
BDB040645
|
BDBM762513
NCCCn1ccc2cncc(Nc3ccc(I)cc3F)c2c1=O
|
C17H16FIN4O 438.244000 |
JRHFMDUXQBSIPQ-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762513; PubChem:CID148110942
|
Local ready
Direct docking supported
|
|
E3L040646
BDB040646
|
BDBM762515
O=C(O)Cn1ccc2cncc(Nc3ccc(I)cc3F)c2c1=O
|
C16H11FIN3O3 439.184000 |
DGLHJWQEOBFOEH-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762515; PubChem:CID147356666
|
Local ready
Direct docking supported
|
|
E3L040647
BDB040647
|
BDBM762516
COC(=O)Cn1ccc2cncc(Nc3ccc(I)cc3F)c2c1=O
|
C17H13FIN3O3 453.211000 |
FGWGHRIVKMAJLF-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762516; PubChem:CID147498049
|
Local ready
Direct docking supported
|
|
E3L040648
BDB040648
|
BDBM762517
O=c1c2c(Nc3ccc(I)cc3F)cncc2ccn1O
|
C14H9FIN3O2 397.147000 |
YOQLQKYGYGPPSO-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762517; PubChem:CID149397023
|
Local ready
Direct docking supported
|
|
E3L040649
BDB040649
|
BDBM762518
O=c1c2c(Nc3ccc(I)cc3F)cncc2ccn1OCCO
|
C16H13FIN3O3 441.200000 |
FFVCAWOCVGAVGC-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762518; PubChem:CID147492599
|
Local ready
Direct docking supported
|
|
E3L040650
BDB040650
|
BDBM762519
O=C1c2c(cncc2Nc2ccc(I)cc2F)CCN1OCCO
|
C16H15FIN3O3 443.216000 |
VCDKRXDAIHWAIJ-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762519; PubChem:CID153022136
|
Local ready
Direct docking supported
|
|
E3L040651
BDB040651
|
BDBM762520
CCON1CCc2cncc(Nc3ccc(I)cc3F)c2C1=O
|
C16H15FIN3O2 427.217000 |
BLCVWLJYBUZVMT-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762520; PubChem:CID147103564
|
Local ready
Direct docking supported
|
|
E3L040652
BDB040652
|
BDBM762521
O=C1NCCc2cncc(Nc3ccc(I)cc3F)c21
|
C14H11FIN3O 383.164000 |
FUGXXWZBNLPKHX-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM762521; PubChem:CID147569773
|
Local ready
Direct docking supported
|
|
E3L040653
BDB040653
|
US20250257055, Example 1
O=C1N[C@]2(CCc3cc(-c4cnn(C5CN(C6COC6)C5)c4)ccc32)C(=O)N1CC(=O)N(Cc1ccc(F)cc1)C1(C(F)(F)F)COC1
|
C33H32F4N6O5 668.648000 |
ACMLFDGZWOXKDL-YTTGMZPUSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764564; PubChem:CID176861994
|
Local ready
Direct docking supported
|
|
E3L040654
BDB040654
|
US20250257055, Example 2
CN1CC(F)(Cn2cc(-c3ccc4c(c3)CC[C@]43NC(=O)N(CC(=O)N(Cc4ccc(F)cc4)C4(C(F)(F)F)COC4)C3=O)cn2)C1
|
C32H31F5N6O4 658.628000 |
FCKNZOUTYCLFSY-HKBQPEDESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764565; PubChem:CID176862010
|
Local ready
Direct docking supported
|
|
E3L040655
BDB040655
|
US20250257055, Example 3
O=C1N[C@]2(C[C@@H](F)c3cc(-c4cnn(C5CN(C6COC6)C5)c4)ccc32)C(=O)N1CC(=O)N(Cc1ccc(F)cc1)C1(C(F)(F)F)COC1
|
C33H31F5N6O5 686.638000 |
MRECOMFGRKBNFR-ZUKKLESISA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764566; PubChem:CID176862012
|
Local ready
Direct docking supported
|
|
E3L040656
BDB040656
|
US20250257055, Example 4
O=C1N[C@]2(C[C@@H](F)c3cc(-c4cnn(C5CN(C6COC6)C5)c4)ccc32)C(=O)N1CC(=O)N(Cc1ccc(F)cc1)C1(C(F)(F)F)CC(F)(F)C1
|
C34H31F7N6O4 720.646000 |
BKCHTXXAFMJELI-SYBRLPANSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764567; PubChem:CID176861988
|
Local ready
Direct docking supported
|
|
E3L040657
BDB040657
|
US20250257055, Example 5
O=C1N[C@]2(CCc3cc(-c4cnn(C5CN(C6COC6)C5)c4)ccc32)C(=O)N1CC(=O)N(Cc1ccc(F)cc1)C1(C(F)(F)F)CC(F)(F)C1
|
C34H32F6N6O4 702.656000 |
LQHXVSXJYDRTMV-XIFFEERXSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764568; PubChem:CID176861970
|
Local ready
Direct docking supported
|
|
E3L040658
BDB040658
|
US20250257055, Example 6
O=C1N[C@]2(CCc3cc(-c4cnn(C5CN(C6COC6)C5)c4)ccc32)C(=O)N1CC(=O)N(Cc1ccc(F)cn1)C1(C(F)(F)F)COC1
|
C32H31F4N7O5 669.636000 |
NEJWEYMAGKTECX-HKBQPEDESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764569; PubChem:CID176862005
|
Local ready
Direct docking supported
|
|
E3L040659
BDB040659
|
US20250257055, Example 7
O=C1N[C@]2(C[C@@H](F)c3cc(-c4cnn(C5CN(C6COC6)C5)c4)ccc32)C(=O)N1CC(=O)N(Cc1ccc(F)cn1)C1(C(F)(F)F)COC1
|
C32H30F5N7O5 687.626000 |
MWZMDGHSCHBFBT-NEEKEDPPSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764570; PubChem:CID176861980
|
Local ready
Direct docking supported
|
|
E3L040660
BDB040660
|
US20250257055, Example 8
O=C1N[C@]2(CCc3cc(-c4cnn(C5CN(C6COC6)C5)c4)ccc32)C(=O)N1CC(=O)N(Cc1ccc(F)cn1)C1(C(F)(F)F)CC(F)(F)C1
|
C33H31F6N7O4 703.644000 |
HJWGZLUWFDESBA-YTTGMZPUSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764571; PubChem:CID176861972
|
Local ready
Direct docking supported
|