| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L040681
BDB040681
|
US20250257055, Example 30
CCn1cc(-c2ccc3c(c2)[C@H](F)C[C@]32NC(=O)N(CC(=O)N(Cc3ccc(F)cc3)C3(C(F)(F)F)CN(C)C3)C2=O)cn1
|
C30H29F5N6O3 616.591000 |
AMMLBLXPKVTDJJ-GIGWZHCTSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764592; PubChem:CID176862016
|
Local ready
Direct docking supported
|
|
E3L040682
BDB040682
|
US20250257055, Example 31
CC(C)n1cc(-c2ccc3c(c2)[C@H](F)C[C@]32NC(=O)N(CC(=O)N(Cc3ccc(F)cc3)C3(C(F)(F)F)CN(C)C3)C2=O)cn1
|
C31H31F5N6O3 630.618000 |
GMWJOJAVQDJWLP-RNAHPLFWSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764593; PubChem:CID176862009
|
Local ready
Direct docking supported
|
|
E3L040683
BDB040683
|
US20250257055, Example 32
CCn1cc(-c2ccc3c(c2)[C@H](F)C[C@]32NC(=O)N(CC(=O)N(Cc3ccc(F)cn3)C3(C(F)(F)F)CN(C)C3)C2=O)cn1
|
C29H28F5N7O3 617.579000 |
OJCJBSVDYBMCLG-LXFBAYGMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764594; PubChem:CID176862015
|
Local ready
Direct docking supported
|
|
E3L040684
BDB040684
|
US20250257055, Example 33
CC(C)n1cc(-c2ccc3c(c2)[C@H](F)C[C@]32NC(=O)N(CC(=O)N(Cc3ccc(F)cn3)C3(C(F)(F)F)CN(C)C3)C2=O)cn1
|
C30H30F5N7O3 631.606000 |
BEGITSSNCCVVNP-GIGWZHCTSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764595; PubChem:CID176861968
|
Local ready
Direct docking supported
|
|
E3L040685
BDB040685
|
US20250257055, Example 34
CN1CC(N(Cc2ccc(F)cn2)C(=O)CN2C(=O)N[C@]3(C[C@@H](F)c4cc(-c5cnn(C6CCC6)c5)ccc43)C2=O)(C(F)(F)F)C1
|
C31H30F5N7O3 643.617000 |
AXUWOPMZIMEOGX-RNAHPLFWSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764596; PubChem:CID176861990
|
Local ready
Direct docking supported
|
|
E3L040686
BDB040686
|
US20250257055, Example 35
CN1CC(N(Cc2ccc(C(F)(F)F)cc2)C(=O)CN2C(=O)N[C@]3(C[C@@H](F)c4cc(-c5cnn(C)c5)ccc43)C2=O)(C(F)(F)F)C1
|
C30H27F7N6O3 652.571000 |
NXUZCURQFURQPB-LXFBAYGMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM764597; PubChem:CID176861977
|
Local ready
Direct docking supported
|
|
E3L040687
BDB040687
|
BDBM765774
O=C1CCC(c2c(F)cc(N3CC(NC(=O)OCC4CC5(CCC5)C4)C3)cc2F)C(=O)N1
|
C23H27F2N3O4 447.482000 |
IXZNKWIZJRGUSP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765774; PubChem:CID171541181
|
Local ready
Direct docking supported
|
|
E3L040688
BDB040688
|
BDBM765775
COc1c(N2CC(C)(NC(=O)OCC3CC4(CCC4)C3)C2)ccc(C2CCC(=O)NC2=O)c1F
|
C25H32FN3O5 473.545000 |
XEUZOKIVSMPTKW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765775; PubChem:CID171541256
|
Local ready
Direct docking supported
|
|
E3L040689
BDB040689
|
CDK2 degrader 1
O=C1CCC(c2c(F)cc(N3CC(NC(=O)OC[C@@H]4C[C@H]5CC[C@@H]4C5)C3)cc2F)C(=O)N1
|
C23H27F2N3O4 447.482000 |
KUTYUVCSHRYCRH-QYCFJQJSSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765776; PubChem:CID171540987
|
Local ready
Direct docking supported
|
|
E3L040690
BDB040690
|
BDBM765777
O=C1CCC(c2c(F)cc(N3CC(NC(=O)OC45CC(C(=O)c6ccccc6)(C4)C5)C3)cc2F)C(=O)N1
|
C27H25F2N3O5 509.509000 |
XGUZWITYIMHDPA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765777; PubChem:CID171541247
|
Local ready
Direct docking supported
|
|
E3L040691
BDB040691
|
BDBM765778
O=C1CCC(c2c(F)cc(N3CC(NC(=O)OC4CN(C(=O)N5Cc6ccccc6C5)C4)C3)cc2F)C(=O)N1
|
C27H27F2N5O5 539.539000 |
QTTHIYACYMRYLP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765778; PubChem:CID171540844
|
Local ready
Direct docking supported
|
|
E3L040692
BDB040692
|
BDBM765779
Cc1ccnc(N2CC(OC(=O)NC3CN(c4cc(F)c(C5CCC(=O)NC5=O)c(F)c4)C3)C2)c1
|
C24H25F2N5O4 485.491000 |
ZGQHHJROSOPECR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765779; PubChem:CID171540859
|
Local ready
Direct docking supported
|
|
E3L040693
BDB040693
|
BDBM765780
Cn1nccc1N1CC(OC(=O)NC2CN(c3cc(F)c(C4CCC(=O)NC4=O)c(F)c3)C2)C1
|
C22H24F2N6O4 474.468000 |
SMVYGMLXROJBPU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765780; PubChem:CID171540980
|
Local ready
Direct docking supported
|
|
E3L040694
BDB040694
|
BDBM765781
CN(C(=O)N1CC(OC(=O)NC2CN(c3cc(F)c(C4CCC(=O)NC4=O)c(F)c3)C2)C1)c1cccc(Cl)c1
|
C26H26ClF2N5O5 561.973000 |
CVOSRXFICVQGAI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765781; PubChem:CID171540830
|
Local ready
Direct docking supported
|
|
E3L040695
BDB040695
|
BDBM765782
O=C1CCC(c2c(F)cc(N3CC(NC(=O)OC4CN(C(=O)N5CCc6ccccc65)C4)C3)cc2F)C(=O)N1
|
C27H27F2N5O5 539.539000 |
DXOCNJNNJCUOND-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765782; PubChem:CID171540857
|
Local ready
Direct docking supported
|
|
E3L040696
BDB040696
|
BDBM765783
Cc1cccc(N(C)C(=O)N2CC(OC(=O)NC3CN(c4cc(F)c(C5CCC(=O)NC5=O)c(F)c4)C3)C2)c1
|
C27H29F2N5O5 541.555000 |
VMOBPDSFPKGGMV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765783; PubChem:CID171540995
|
Local ready
Direct docking supported
|
|
E3L040697
BDB040697
|
BDBM765784
CN(C(=O)N1CC(OC(=O)NC2(C(F)(F)F)CN(c3cc(F)c(C4CCC(=O)NC4=O)c(F)c3)C2)C1)C1CC1
|
C24H26F5N5O5 559.492000 |
LFIFQXKWBNIYLV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765784; PubChem:CID171541074
|
Local ready
Direct docking supported
|
|
E3L040698
BDB040698
|
BDBM765785
CN(C(=O)N1CC(OC(=O)NC2(C)CN(c3cc(F)c(C4CCC(=O)NC4=O)c(F)c3)C2)C1)C1CC1
|
C24H29F2N5O5 505.522000 |
OQFSJDPOVSMWQU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765785; PubChem:CID171541162
|
Local ready
Direct docking supported
|
|
E3L040699
BDB040699
|
BDBM765786
COc1ccc(N(C)C(=O)N2CC(OC(=O)NC3CN(c4cc(F)c(C5CCC(=O)NC5=O)c(F)c4)C3)C2)cc1
|
C27H29F2N5O6 557.554000 |
LQXLMDSSFKFBRW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765786; PubChem:CID171541123
|
Local ready
Direct docking supported
|
|
E3L040700
BDB040700
|
BDBM765787
CN(C)C(=O)N1CC(OC(=O)NC2(C)CN(c3cc(F)c(C4CCC(=O)NC4=O)c(F)c3)C2)C1
|
C22H27F2N5O5 479.484000 |
BZFPUFLEHCVIMC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM765787; PubChem:CID171541359
|
Local ready
Direct docking supported
|