| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005181
BDB005181
|
BDBM119724
O=C(NC1CCC(O)CC1)[C@@H]1N[C@H](CC2CCCC2)[C@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C30H36Cl2FN3O2 560.541000 |
MIXMBJVFBHEWEI-KMXBVAHZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM119724; PubChem:CID91663832
|
Local ready
Direct docking supported
|
|
E3L005182
BDB005182
|
BDBM119725
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C28H32Cl2FN3O3 548.486000 |
MZBOZBMARIQZGX-GRRGFIRHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119725
|
Local ready
Direct docking supported
|
|
E3L005183
BDB005183
|
BDBM119726
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C29H34Cl2FN3O3 562.513000 |
IDKAKZRYYDCJDU-AEPXTFJPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119726
|
Local ready
Direct docking supported
|
|
E3L005184
BDB005184
|
US8680132, MI-77302 (TFA salt)
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C29H34Cl2FN3O3 562.513000 |
IDKAKZRYYDCJDU-MCVFFFNQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM119728; PubChem:CID69888109
|
Local ready
Direct docking supported
|
|
E3L005185
BDB005185
|
BDBM119729
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(F)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C28H32ClF2N3O3 532.031000 |
CUMRPCQMSXHYEE-GRRGFIRHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119729
|
Local ready
Direct docking supported
|
|
E3L005186
BDB005186
|
BDBM119730
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(F)c(F)cc12
|
C28H31ClF3N3O3 550.021000 |
MZLPNMUZFAVXQN-SDJDJFSXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119730
|
Local ready
Direct docking supported
|
|
E3L005187
BDB005187
|
BDBM119731
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C28H31Cl2F2N3O3 566.476000 |
OTLQVUTVHXHUHB-SDJDJFSXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119731
|
Local ready
Direct docking supported
|
|
E3L005188
BDB005188
|
BDBM119732
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C28H33Cl2N3O3 530.496000 |
DFNKYRCFAIHHQB-KCEIGVIJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119732
|
Local ready
Direct docking supported
|
|
E3L005189
BDB005189
|
BDBM119733
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C28H32Cl2FN3O3 548.486000 |
GRCKTMFGZSJBOA-ZYCFHTJLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119733
|
Local ready
Direct docking supported
|
|
E3L005190
BDB005190
|
BDBM119734
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1c2ccc(Cl)c1F
|
C28H31Cl2F2N3O3 566.476000 |
MJFDGWGZRHSAFF-QNKOVJCOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119734
|
Local ready
Direct docking supported
|
|
E3L005191
BDB005191
|
BDBM119735
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(F)c2F)[C@]12C(=O)Nc1c2ccc(Cl)c1F
|
C28H31ClF3N3O3 550.021000 |
SXAAXEGAEPWLGA-QNKOVJCOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119735
|
Local ready
Direct docking supported
|
|
E3L005192
BDB005192
|
BDBM119736
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(C)(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C30H36Cl2FN3O3 576.540000 |
FXRIGYNVVHBRGS-WYSKKBERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119736
|
Local ready
Direct docking supported
|
|
E3L005193
BDB005193
|
BDBM119737
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cc(F)cc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C28H32Cl2FN3O3 548.486000 |
MZZBCDOKTOUJQI-KCEIGVIJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119737
|
Local ready
Direct docking supported
|
|
E3L005194
BDB005194
|
BDBM119738
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(F)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C29H34ClF2N3O3 546.058000 |
YRDPNDOUYALHLI-AEPXTFJPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM119738; PubChem:CID53476874
|
Local ready
Direct docking supported
|
|
E3L005195
BDB005195
|
BDBM119739
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C29H33Cl2F2N3O3 580.503000 |
ZGYJDQYOIFAXED-DJJHDAFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119739
|
Local ready
Direct docking supported
|
|
E3L005196
BDB005196
|
BDBM119740
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(F)c(F)cc12
|
C29H33ClF3N3O3 564.048000 |
CPVLFAPAIXRGNV-DJJHDAFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM119740; PubChem:CID53476875
|
Local ready
Direct docking supported
|
|
E3L005197
BDB005197
|
BDBM119741
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C29H35Cl2N3O3 544.523000 |
PSABHJAMVJLCQH-JVUXWEBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM119741; PubChem:CID53476878
|
Local ready
Direct docking supported
|
|
E3L005198
BDB005198
|
US8680132, CB061-Isomer B
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C29H34Cl2FN3O3 562.513000 |
SJAWWEKCOBDMOT-NZVKTDFMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM119742; PubChem:CID53476987
|
Local ready
Direct docking supported
|
|
E3L005199
BDB005199
|
BDBM119743
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(C)(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C30H36Cl2FN3O3 576.540000 |
FXRIGYNVVHBRGS-WYSKKBERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119743
|
Local ready
Direct docking supported
|
|
E3L005200
BDB005200
|
BDBM119744
CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cc(Cl)ccc2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C28H32Cl2FN3O3 548.486000 |
UPRIKRXEOKHMPL-ZYCFHTJLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM119744
|
Local ready
Direct docking supported
|