| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005241
BDB005241
|
BDBM129733
COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C33H34Cl2N4O3 605.566000 |
SREKLQZSZRMJMY-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM129733; PubChem:CID86766859
|
Local ready
Direct docking supported
|
|
E3L005242
BDB005242
|
BDBM129734
COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C34H34Cl2N4O4 633.576000 |
UALRGMCASGTUKL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129734; PubChem:CID86766860
|
Local ready
Direct docking supported
|
|
E3L005243
BDB005243
|
BDBM129735
COc1ccc(C(=O)N2CC(O)C2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C33H32Cl2N4O4 619.549000 |
HDXSASRATCKTIY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129735; PubChem:CID71678430
|
Local ready
Direct docking supported
|
|
E3L005244
BDB005244
|
BDBM129736
COc1cnccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C28H26Cl2N4O2 521.448000 |
CATIIVQXQSCWDS-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129736; PubChem:CID86766861
|
Local ready
Direct docking supported
|
|
E3L005245
BDB005245
|
BDBM129737
COc1ccc(CN)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H30Cl2N4O2 549.502000 |
ZESYAYINYFJRIY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129737; PubChem:CID86707772
|
Local ready
Direct docking supported
|
|
E3L005246
BDB005246
|
BDBM129738
COc1ccc(CNC(C)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O3 591.539000 |
PZKACSRRIGOWPK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129738; PubChem:CID86707771
|
Local ready
Direct docking supported
|
|
E3L005247
BDB005247
|
BDBM129739
COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H29Cl2N3O3 550.486000 |
YJTBLUMJJBCGIZ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129739; PubChem:CID78140228
|
Local ready
Direct docking supported
|
|
E3L005248
BDB005248
|
BDBM129740
COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H27Cl2N3O3 536.459000 |
WSMVHSISVPPRHW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129740; PubChem:CID86766862
|
Local ready
Direct docking supported
|
|
E3L005249
BDB005249
|
BDBM129741
COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H24Cl2FN3O3 540.422000 |
BPFADFDGSWMADD-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129741; PubChem:CID71678432
|
Local ready
Direct docking supported
|
|
E3L005250
BDB005250
|
BDBM129742
COc1cc(CO)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H27Cl2N3O3 536.459000 |
LWRJMBMVSJURSA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129742; PubChem:CID71678433
|
Local ready
Direct docking supported
|
|
E3L005251
BDB005251
|
BDBM129743
COc1cc(CO)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H29Cl2N3O3 550.486000 |
HKLMUYUAAOFOGO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129743; PubChem:CID86766863
|
Local ready
Direct docking supported
|
|
E3L005252
BDB005252
|
BDBM129744
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C31H30Cl2N4O3 577.512000 |
IFVDWMMHXKFNKA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129744; PubChem:CID78147787
|
Local ready
Direct docking supported
|
|
E3L005253
BDB005253
|
BDBM129745
COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H24Cl2N4O2 531.443000 |
WJPIXIHKBIGAJF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129745; PubChem:CID86766864
|
Local ready
Direct docking supported
|
|
E3L005254
BDB005254
|
BDBM129746
COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C33H32Cl2N4O4 619.549000 |
PFKBLSFRCDFQGP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129746; PubChem:CID71678434
|
Local ready
Direct docking supported
|
|
E3L005255
BDB005255
|
BDBM129747
COc1cc(C#N)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H24Cl2N4O2 531.443000 |
WLIKZKKQRBMQQT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129747; PubChem:CID86766865
|
Local ready
Direct docking supported
|
|
E3L005256
BDB005256
|
BDBM129748
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C27H25Cl2N5O3 538.435000 |
SDGHDCDOONCQMU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129748; PubChem:CID86766866
|
Local ready
Direct docking supported
|
|
E3L005257
BDB005257
|
BDBM129749
COc1cc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)nn1
|
C27H25Cl2N5O3 538.435000 |
ZRFZEUZVIQWOPQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129749; PubChem:CID86766867
|
Local ready
Direct docking supported
|
|
E3L005258
BDB005258
|
BDBM129750
COc1ccc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C29H28Cl2N4O3 551.474000 |
WKBFTMYURJKOSP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129750; PubChem:CID71678601
|
Local ready
Direct docking supported
|
|
E3L005259
BDB005259
|
BDBM129751
COc1ncncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C27H25Cl2N5O2 522.436000 |
ZINGSQHFPIBXGS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129751; PubChem:CID86766868
|
Local ready
Direct docking supported
|
|
E3L005260
BDB005260
|
BDBM129752
CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C27H26Cl2N6O2 537.451000 |
BNIPFQDYJLTHKR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129752; PubChem:CID86766869
|
Local ready
Direct docking supported
|