| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005521
BDB005521
|
BDBM130029
COc1nc(N2CCS(=O)(=O)CC2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C30H27ClFN7O4S 636.109000 |
GQNLAZRLGGNLKQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130029; PubChem:CID86767063
|
Local ready
Direct docking supported
|
|
E3L005522
BDB005522
|
BDBM130030
COc1nc(N2CCC[C@H](O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C31H29ClFN7O3 602.070000 |
NQVJVPPOCXEUDP-DQUNLGLBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130030; PubChem:CID71678263
|
Local ready
Direct docking supported
|
|
E3L005523
BDB005523
|
BDBM130031
COC[C@@H](C)n1c(-c2cnc(N)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C26H23Cl2FN6O3 557.413000 |
XBFIBOYFIFCARJ-ILRUXTBWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130031; PubChem:CID86767064
|
Local ready
Direct docking supported
|
|
E3L005524
BDB005524
|
BDBM130032
COC[C@@H](C)n1c(-c2cnc(N)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C27H26Cl2N6O3 553.450000 |
BSZWJOXGSAQMEI-JGHKVMFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130032; PubChem:CID86767065
|
Local ready
Direct docking supported
|
|
E3L005525
BDB005525
|
BDBM130033
COc1ncc(-c2nc3c(n2[C@H](C)CO)[C@@H](c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C26H22Cl2FN5O4 558.397000 |
ZIVYGCBNCGFBLY-LRTDBIEQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130033; PubChem:CID71678264
|
Local ready
Direct docking supported
|
|
E3L005526
BDB005526
|
BDBM130034
COc1ncc(-c2nc3c(n2[C@H](C)CO)[C@H](c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C26H22Cl2FN5O4 558.397000 |
ZIVYGCBNCGFBLY-ASSNKEHSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130034; PubChem:CID71678265
|
Local ready
Direct docking supported
|
|
E3L005527
BDB005527
|
BDBM130035
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C27H24Cl2FN5O4 572.424000 |
DGLXELIGVRDJBG-PEBXRYMYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM130035; PubChem:CID71678258
|
Local ready
Direct docking supported
|
|
E3L005528
BDB005528
|
BDBM130036
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C27H24Cl2FN5O4 572.424000 |
DGLXELIGVRDJBG-JLCFBVMHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130036; PubChem:CID71678266
|
Local ready
Direct docking supported
|
|
E3L005529
BDB005529
|
BDBM130037
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C27H26Cl2N6O5 585.448000 |
JHZIDLJOAGDEQT-CKAQCJTGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130037; PubChem:CID86767066
|
Local ready
Direct docking supported
|
|
E3L005530
BDB005530
|
BDBM130038
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C27H26Cl2N6O5 585.448000 |
XFVPAUGALMSDDA-CKAQCJTGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130038; PubChem:CID71678267
|
Local ready
Direct docking supported
|
|
E3L005531
BDB005531
|
BDBM130039
COC[C@@H](C)n1c(-c2cnc(N(C)C)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H29Cl2N7O4 598.491000 |
IRKAVWLRLAKNOM-JGHKVMFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM130039
|
Local ready
Direct docking supported
|
|
E3L005532
BDB005532
|
BDBM130040
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C27H26Cl2N6O5 585.448000 |
JHZIDLJOAGDEQT-SZNDQCEHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130040; PubChem:CID71678437
|
Local ready
Direct docking supported
|
|
E3L005533
BDB005533
|
BDBM130041
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C27H26Cl2N6O5 585.448000 |
JHZIDLJOAGDEQT-SPLOXXLWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130041; PubChem:CID71678438
|
Local ready
Direct docking supported
|
|
E3L005534
BDB005534
|
BDBM130042
COC[C@@H](C)n1c(-c2cnc(N(C)C)nc2OC)nc2c1[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H29Cl2N7O4 598.491000 |
IRKAVWLRLAKNOM-QRQCRPRQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM130042
|
Local ready
Direct docking supported
|
|
E3L005535
BDB005535
|
BDBM130043
COC[C@@H](C)n1c(-c2cnc(N(C)C)nc2OC)nc2c1[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H29Cl2N7O4 598.491000 |
IRKAVWLRLAKNOM-IVZQSRNASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM130043
|
Local ready
Direct docking supported
|
|
E3L005536
BDB005536
|
BDBM130044
COc1ncc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C29H23ClFN5O4 559.985000 |
HGWJNENSRSSMNF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130044; PubChem:CID86767067
|
Local ready
Direct docking supported
|
|
E3L005537
BDB005537
|
BDBM130045
COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(C#N)c(F)c2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
|
C27H21ClF2N6O3 550.953000 |
VPYAOHKBGSECIH-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130045; PubChem:CID86767068
|
Local ready
Direct docking supported
|
|
E3L005538
BDB005538
|
BDBM130047
CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCCCCCCCC(=O)N2CC[C@H]3CC[C@@H](c4nc5c(-c6ccccc6)cccc5[nH]4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](c3nc4c(-c5ccccc5)cccc4[nH]3)N2C1=O
|
C64H82N12O6 1115.438000 |
UVNKFINNYRAWNE-XAZFDRPSSA-N | Q13489 | Baculoviral IAP repeat-containing protein 3 |
BindingDB
BindingDB:BDBM130047
|
Local ready
Direct docking supported
|
|
E3L005539
BDB005539
|
BDBM130048
CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCOCCCCC(=O)N2CC[C@H]3CC[C@@H](c4nc5c(-c6ccccc6)cccc5[nH]4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](c3nc4c(-c5ccccc5)cccc4[nH]3)N2C1=O
|
C62H78N12O7 1103.383000 |
ZPYWWTKXCOYJBE-LLUFGHGUSA-N | Q13489 | Baculoviral IAP repeat-containing protein 3 |
BindingDB
BindingDB:BDBM130048
|
Local ready
Direct docking supported
|
|
E3L005540
BDB005540
|
BDBM130049
CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCCCC(=O)N2CC[C@H]3CC[C@@H](c4nc5c(-c6ccccc6)cccc5[nH]4)N3C(=O)[C@@H](NC(=O)[C@H](C)NC)C2)CC[C@H]2CC[C@@H](c3nc4c(-c5ccccc5)cccc4[nH]3)N2C1=O
|
C58H70N12O6 1031.276000 |
QWLVLLKEBKWIRS-HCTRBPPDSA-N | Q13489 | Baculoviral IAP repeat-containing protein 3 |
BindingDB
BindingDB:BDBM130049
|
Local ready
Direct docking supported
|