| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005461
BDB005461
|
BDBM129959
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C29H22ClFN6O2 540.986000 |
ZZPSXZGTKBOVMU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129959; PubChem:CID86767008
|
Local ready
Direct docking supported
|
|
E3L005462
BDB005462
|
BDBM129960
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C28H22Cl2FN5O2 550.421000 |
SPGQNOMPKOGAHP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129960; PubChem:CID86767009
|
Local ready
Direct docking supported
|
|
E3L005463
BDB005463
|
BDBM129961
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C31H27ClN6O2 551.050000 |
RJEPDAUFWBISTE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129961; PubChem:CID86767010
|
Local ready
Direct docking supported
|
|
E3L005464
BDB005464
|
BDBM129962
COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nc(C)n1)C2=O
|
C27H27ClN6O3 519.005000 |
AAJIJBGNQAJINX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129962; PubChem:CID71680445
|
Local ready
Direct docking supported
|
|
E3L005465
BDB005465
|
BDBM129963
COc1nn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C26H22Cl2FN5O3 542.398000 |
SGXGJFAKEPHRSK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129963; PubChem:CID71680446
|
Local ready
Direct docking supported
|
|
E3L005466
BDB005466
|
BDBM129964
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cn1)N(c1cc(Cl)ccc1C)C2=O
|
C27H27Cl2N7O2 552.466000 |
LQUVMDCDNGTXTQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129964; PubChem:CID86767011
|
Local ready
Direct docking supported
|
|
E3L005467
BDB005467
|
BDBM129965
CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)c(F)c2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C27H22ClF2N7O2 549.969000 |
GWIMAUJVFQGLFF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129965; PubChem:CID86767012
|
Local ready
Direct docking supported
|
|
E3L005468
BDB005468
|
BDBM129966
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cccc(Cl)c1F)C2=O
|
C28H24ClF2N7O2 563.996000 |
LUZOCJAWBOFFDE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129966; PubChem:CID86767013
|
Local ready
Direct docking supported
|
|
E3L005469
BDB005469
|
BDBM129969
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H22Cl2FN5O2 550.421000 |
ZKMWZPFDSPCJMI-VWLOTQADSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129969; PubChem:CID86767015
|
Local ready
Direct docking supported
|
|
E3L005470
BDB005470
|
BDBM129970
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H22Cl2FN5O2 550.421000 |
ZKMWZPFDSPCJMI-RUZDIDTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129970; PubChem:CID71677936
|
Local ready
Direct docking supported
|
|
E3L005471
BDB005471
|
BDBM129971
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C30H25ClN6O2 537.023000 |
ACEGVIRLYYSHCR-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129971; PubChem:CID86767016
|
Local ready
Direct docking supported
|
|
E3L005472
BDB005472
|
BDBM129972
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C30H25ClN6O2 537.023000 |
ACEGVIRLYYSHCR-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129972; PubChem:CID86767017
|
Local ready
Direct docking supported
|
|
E3L005473
BDB005473
|
BDBM129973
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C29H22ClFN6O2 540.986000 |
JSRNNPIFXLIKLR-SANMLTNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129973; PubChem:CID86767018
|
Local ready
Direct docking supported
|
|
E3L005474
BDB005474
|
BDBM129974
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C29H22ClFN6O2 540.986000 |
JSRNNPIFXLIKLR-AREMUKBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129974; PubChem:CID86767019
|
Local ready
Direct docking supported
|
|
E3L005475
BDB005475
|
BDBM129975
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H24ClFN6O4 562.989000 |
VFTRVCSLFJWRQT-NKTHEXPSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129975; PubChem:CID86767020
|
Local ready
Direct docking supported
|
|
E3L005476
BDB005476
|
BDBM129976
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H27ClN6O4 559.026000 |
DJZBBHGMHHTXRK-BPNWFJGMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129976; PubChem:CID71677937
|
Local ready
Direct docking supported
|
|
E3L005477
BDB005477
|
BDBM129977
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C27H24Cl2FN5O4 572.424000 |
HOSIPFDBMORRGG-HNNQXCQYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129977; PubChem:CID86767021
|
Local ready
Direct docking supported
|
|
E3L005478
BDB005478
|
BDBM129978
COC[C@@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C27H24Cl2FN5O4 572.424000 |
DGLXELIGVRDJBG-HNNQXCQYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129978; PubChem:CID86767022
|
Local ready
Direct docking supported
|
|
E3L005479
BDB005479
|
BDBM129979
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(F)c(C)c2)C3=O)c(OC)n1
|
C27H25ClFN5O3 521.980000 |
XOPIGYYHLXYFSU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129979; PubChem:CID86767023
|
Local ready
Direct docking supported
|
|
E3L005480
BDB005480
|
BDBM129980
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)ccc2OC)C3=O)c(OC)n1
|
C28H28ClN5O4 534.016000 |
WKWPLVZECQVBIG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129980; PubChem:CID86767024
|
Local ready
Direct docking supported
|