| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005481
BDB005481
|
BDBM129981
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)nc(C)n2)C3=O)c(OC)n1
|
C26H26ClN7O3 519.993000 |
PHJJUKYJJYGEDR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129981; PubChem:CID86767025
|
Local ready
Direct docking supported
|
|
E3L005482
BDB005482
|
BDBM129982
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C25H21Cl2FN6O2 527.387000 |
XCYXFLGIXMWOGQ-FQEVSTJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129982; PubChem:CID86767026
|
Local ready
Direct docking supported
|
|
E3L005483
BDB005483
|
BDBM129983
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C25H21Cl2FN6O2 527.387000 |
XCYXFLGIXMWOGQ-HXUWFJFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129983; PubChem:CID86767027
|
Local ready
Direct docking supported
|
|
E3L005484
BDB005484
|
BDBM129984
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C25H21Cl2FN6O2 527.387000 |
LETKMLJFIJMGIB-FQEVSTJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129984; PubChem:CID86767028
|
Local ready
Direct docking supported
|
|
E3L005485
BDB005485
|
BDBM129985
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C25H21Cl2FN6O2 527.387000 |
LETKMLJFIJMGIB-HXUWFJFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129985; PubChem:CID86767029
|
Local ready
Direct docking supported
|
|
E3L005486
BDB005486
|
BDBM129986
COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(C)c1)C2=O
|
C28H26ClFN4O3 520.992000 |
IXIUWZAYDKWTRD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129986; PubChem:CID86767030
|
Local ready
Direct docking supported
|
|
E3L005487
BDB005487
|
BDBM129987
COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)ccc1OC)C2=O
|
C29H29ClN4O4 533.028000 |
NEUPLRINCBEPRG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129987; PubChem:CID71677938
|
Local ready
Direct docking supported
|
|
E3L005488
BDB005488
|
BDBM129995
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cn2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C26H24Cl2N6O3 539.423000 |
WKIVYIKJKROXBR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129995; PubChem:CID86767037
|
Local ready
Direct docking supported
|
|
E3L005489
BDB005489
|
BDBM129996
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H26ClFN8O3 577.020000 |
QDPYELDPBPKJGT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM129996
|
Local ready
Direct docking supported
|
|
E3L005490
BDB005490
|
BDBM129997
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C27H23ClFN7O4 563.977000 |
WZABXGKXESRDLT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129997; PubChem:CID86767038
|
Local ready
Direct docking supported
|
|
E3L005491
BDB005491
|
BDBM129998
CC(C)n1c(-c2c[nH]c(=O)[nH]c2=O)nc2c1[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C24H20Cl2N6O4 527.368000 |
FCCVLCAOBRUPSX-SFHVURJKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129998; PubChem:CID136592750
|
Local ready
Direct docking supported
|
|
E3L005492
BDB005492
|
BDBM129999
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C27H27Cl2N7O3 568.465000 |
MLVQWIAMCUTJAS-OAQYLSRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129999; PubChem:CID86767040
|
Local ready
Direct docking supported
|
|
E3L005493
BDB005493
|
BDBM130000
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C27H27Cl2N7O3 568.465000 |
MLVQWIAMCUTJAS-NRFANRHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130000; PubChem:CID86767041
|
Local ready
Direct docking supported
|
|
E3L005494
BDB005494
|
BDBM130001
COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)cnc2O)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
CHOHEJZMEHHXSJ-IBGZPJMESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130001; PubChem:CID71678259
|
Local ready
Direct docking supported
|
|
E3L005495
BDB005495
|
BDBM130002
COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
CHOHEJZMEHHXSJ-LJQANCHMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130002; PubChem:CID89720143
|
Local ready
Direct docking supported
|
|
E3L005496
BDB005496
|
BDBM130003
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C26H23Cl2FN6O4 573.412000 |
RTIUOSDQICRCDW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130003; PubChem:CID86767043
|
Local ready
Direct docking supported
|
|
E3L005497
BDB005497
|
BDBM130004
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C27H26Cl2FN7O3 586.455000 |
OMTCYNMUBUJVEF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130004; PubChem:CID86767044
|
Local ready
Direct docking supported
|
|
E3L005498
BDB005498
|
BDBM130005
COc1ncc(-c2nc3c(n2C(C)C)C(C)(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C27H26Cl2N6O4 569.449000 |
YRRRQSYNWFAILP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130005; PubChem:CID86767045
|
Local ready
Direct docking supported
|
|
E3L005499
BDB005499
|
BDBM130006
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)c(F)c1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C27H26Cl2FN7O3 586.455000 |
UAWRUSGOAINWLC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130006; PubChem:CID86767046
|
Local ready
Direct docking supported
|
|
E3L005500
BDB005500
|
BDBM130007
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H26ClFN8O3 577.020000 |
QDPYELDPBPKJGT-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM130007
|
Local ready
Direct docking supported
|