| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005501
BDB005501
|
BDBM130008
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H26ClFN8O3 577.020000 |
QDPYELDPBPKJGT-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM130008
|
Local ready
Direct docking supported
|
|
E3L005502
BDB005502
|
BDBM130009
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H23Cl2FN6O4 573.412000 |
NJRPTSMHENYHER-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130009; PubChem:CID86767048
|
Local ready
Direct docking supported
|
|
E3L005503
BDB005503
|
BDBM130010
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cc(=O)n2C)C3=O)c(OC)n1
|
C27H27ClN6O4 535.004000 |
KEIMAURQUMCKHJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130010; PubChem:CID86767049
|
Local ready
Direct docking supported
|
|
E3L005504
BDB005504
|
BDBM130011
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cn(C)c2=O)C3=O)c(OC)n1
|
C27H27ClN6O4 535.004000 |
BDEZXXNFTKBOGY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130011; PubChem:CID86767050
|
Local ready
Direct docking supported
|
|
E3L005505
BDB005505
|
BDBM130012
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)cn(C)c1=O)C2=O
|
C28H30ClN7O3 548.047000 |
HODHZDNYDFOHPY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130012; PubChem:CID71678099
|
Local ready
Direct docking supported
|
|
E3L005506
BDB005506
|
BDBM130013
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C(F)F)c2)C3=O)c(OC)n1
|
C26H22Cl2F2N6O4 591.402000 |
QNKCPGVZAQEQIB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130013; PubChem:CID86767051
|
Local ready
Direct docking supported
|
|
E3L005507
BDB005507
|
BDBM130014
CCn1cc(Cl)cc(N2C(=O)c3nc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)c1=O
|
C27H26Cl2N6O4 569.449000 |
PEPZVXADZBSXJG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130014; PubChem:CID86767052
|
Local ready
Direct docking supported
|
|
E3L005508
BDB005508
|
BDBM130015
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C27H26Cl2N6O4 569.449000 |
PTOJLRXUNQDRTQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130015; PubChem:CID86767053
|
Local ready
Direct docking supported
|
|
E3L005509
BDB005509
|
BDBM130016
COc1nc(=O)[nH]cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C25H22Cl2N6O4 541.395000 |
AUOYPKJGZILQEM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130016; PubChem:CID136267625
|
Local ready
Direct docking supported
|
|
E3L005510
BDB005510
|
BDBM130018
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)nnc2OC)C3=O)c(OC)n1
|
C26H26ClN7O4 535.992000 |
COEUCSXIXTVWEF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130018; PubChem:CID71678101
|
Local ready
Direct docking supported
|
|
E3L005511
BDB005511
|
BDBM130019
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cnc2OC)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
CRPHQXQUNFVCTA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130019; PubChem:CID71678102
|
Local ready
Direct docking supported
|
|
E3L005512
BDB005512
|
BDBM130020
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nnc1OC)C2=O
|
C27H29ClN8O3 549.035000 |
FNQNIHGAWFUMNJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130020; PubChem:CID86767055
|
Local ready
Direct docking supported
|
|
E3L005513
BDB005513
|
BDBM130021
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1F)N(c1cccc(Cl)c1F)C2=O
|
C27H24Cl2F2N6O2 573.431000 |
VCPDADGQGVYZGQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130021; PubChem:CID86767056
|
Local ready
Direct docking supported
|
|
E3L005514
BDB005514
|
BDBM130022
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2F)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C26H23Cl2FN6O4 573.412000 |
MFWOYEIJCJSHAY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130022; PubChem:CID86767057
|
Local ready
Direct docking supported
|
|
E3L005515
BDB005515
|
BDBM130023
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1F)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C27H26Cl2FN7O3 586.455000 |
LPTKAFILAPDEPP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130023; PubChem:CID86767058
|
Local ready
Direct docking supported
|
|
E3L005516
BDB005516
|
BDBM130024
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c(F)c(C)nn1C)C2=O
|
C26H28ClFN8O2 539.015000 |
PYMYLGUASVHSHV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130024; PubChem:CID86767059
|
Local ready
Direct docking supported
|
|
E3L005517
BDB005517
|
BDBM130025
COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
KCQKWYOOVWMMJQ-FQEVSTJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130025; PubChem:CID71678103
|
Local ready
Direct docking supported
|
|
E3L005518
BDB005518
|
BDBM130026
COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
KCQKWYOOVWMMJQ-HXUWFJFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130026; PubChem:CID86767060
|
Local ready
Direct docking supported
|
|
E3L005519
BDB005519
|
BDBM130027
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2c(F)c(C4CC4)nn2C)C3=O)c(OC)n1
|
C27H27ClFN7O3 552.010000 |
XAAASJWUJVIXBI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130027; PubChem:CID86767061
|
Local ready
Direct docking supported
|
|
E3L005520
BDB005520
|
BDBM130028
COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1c(F)c(C3CC3)nn1C)C2=O
|
C28H28ClFN6O3 551.022000 |
UMUKEMGFKUMRBP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM130028; PubChem:CID86767062
|
Local ready
Direct docking supported
|