| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005761
BDB005761
|
BDBM135230
CCC1CN(C)C(=O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H33ClN8O3 565.078000 |
IBNMLAFRSXFLFI-IWZNKUOBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135230
|
Local ready
Direct docking supported
|
|
E3L005762
BDB005762
|
BDBM135231
CC1CCC(Cn2c(N3CCCC4COCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C29H34ClN7O3 564.090000 |
SICWPWHPJFOOOQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135231
|
Local ready
Direct docking supported
|
|
E3L005763
BDB005763
|
BDBM135233
CC1CCC(Cn2c(N3CCO[C@@H]4CN(C(=O)OCc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C36H39ClN8O5 699.212000 |
JIOKQGPNZGDGSQ-OSRRSHJASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135233
|
Local ready
Direct docking supported
|
|
E3L005764
BDB005764
|
BDBM135234
CC1CCC(Cn2c(N3CCO[C@@H]4CNCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H33ClN8O3 565.078000 |
ZUQDCSQDHXMAEE-OGRPUPFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135234
|
Local ready
Direct docking supported
|
|
E3L005765
BDB005765
|
BDBM135235
CC1CCC(Cn2c(N3CCO[C@@H]4CN(Cc5ccccc5)CC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C35H39ClN8O3 655.203000 |
PDFUVLMSDRPILV-MMJGTUOCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135235
|
Local ready
Direct docking supported
|
|
E3L005766
BDB005766
|
BDBM135236
C[C@H]1CC[C@H](Cn2c(N3C4CCC3C(O)C4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C27H30ClN7O3 536.036000 |
VPWNCVYUNKKLLJ-UBYUBHBCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135236
|
Local ready
Direct docking supported
|
|
E3L005767
BDB005767
|
BDBM135239
CC(C)[C@@H]1C[C@](C)(O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H36ClN7O3 566.106000 |
KEJDCDUVAHAACN-VCKPOWMGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135239
|
Local ready
Direct docking supported
|
|
E3L005768
BDB005768
|
BDBM135240
COC[C@@H]1C[C@@H](OC)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H34ClN7O4 568.078000 |
BVYPJWOHQGWKAZ-IDPBPBMLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135240
|
Local ready
Direct docking supported
|
|
E3L005769
BDB005769
|
BDBM135241
C[C@H]1CC[C@H](Cn2c(N3CC(O)CC4CCCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C30H36ClN7O3 578.117000 |
ARWOSQLEUJEPTK-LAVZWDNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135241
|
Local ready
Direct docking supported
|
|
E3L005770
BDB005770
|
BDBM135245
CO[C@@H]1C[C@@H](C2(OC)CC2)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C30H36ClN7O4 594.116000 |
INRNFMSJDYSSCT-FQBFJXBRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135245
|
Local ready
Direct docking supported
|
|
E3L005771
BDB005771
|
BDBM135246
CO[C@@H]1C[C@H](C2(OC)CC2)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C30H36ClN7O4 594.116000 |
INRNFMSJDYSSCT-ZUXGEGRZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135246
|
Local ready
Direct docking supported
|
|
E3L005772
BDB005772
|
BDBM135247
CC1CSCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H30ClN7O2S 540.093000 |
OBUZZJVCBDBUOP-XUWMOKQASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135247
|
Local ready
Direct docking supported
|
|
E3L005773
BDB005773
|
BDBM135248
CO[C@@H]1C[C@@H](C(F)F)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C27H30ClF2N7O3 574.032000 |
ADAISLVNSUEGAL-YOZRSPHLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135248
|
Local ready
Direct docking supported
|
|
E3L005774
BDB005774
|
BDBM135249
CCO[C@@H]1C[C@@H](CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C28H33ClFN7O3 570.069000 |
BPYMJMOFMSJXQN-IDPBPBMLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135249
|
Local ready
Direct docking supported
|
|
E3L005775
BDB005775
|
BDBM135250
CCN1C(=O)CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]2CCC[C@H]21
|
C30H35ClN8O3 591.116000 |
BQOOIHJZFSDWRR-MCJPXMOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135250
|
Local ready
Direct docking supported
|
|
E3L005776
BDB005776
|
BDBM135251
COCCO[C@@H]1C[C@@H](C(C)C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C31H40ClN7O4 610.159000 |
SYROLACRZJWBIO-HLFHMTEMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135251
|
Local ready
Direct docking supported
|
|
E3L005777
BDB005777
|
BDBM135252
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC(F)(F)[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H30ClF2N7O3 586.043000 |
COSUZSYWQCTFET-UAWIAZDRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135252
|
Local ready
Direct docking supported
|
|
E3L005778
BDB005778
|
BDBM135253
CC1CO[C@@H]2CCC[C@H]2N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H34ClN7O3 564.090000 |
IZXXIUQNDFXYJM-LPYVOSKBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135253
|
Local ready
Direct docking supported
|
|
E3L005779
BDB005779
|
BDBM135254
CC[C@@H]1[C@@H](C)OCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H34ClN7O3 552.079000 |
RSZUFKICRWRCAL-YTSMVRMISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135254
|
Local ready
Direct docking supported
|
|
E3L005780
BDB005780
|
BDBM135255
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CC(F)(F)C[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H30ClF2N7O3 586.043000 |
SSNKEDLKQOTNHG-AHWCRGGASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135255
|
Local ready
Direct docking supported
|