| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005801
BDB005801
|
BDBM135286
CC([C@H]1CC[C@H](C)CC1)n1c(N2CCOC[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
|
C27H32ClN7O3 538.052000 |
OJRSUGJNZBNYCX-KTBGXXAUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135286
|
Local ready
Direct docking supported
|
|
E3L005802
BDB005802
|
BDBM135288
CC([C@H]1CC[C@H](C)CC1)n1c(N2CC(=O)N(C)C[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
|
C28H33ClN8O3 565.078000 |
JYYSCJMRUZFVRU-KTBGXXAUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135288
|
Local ready
Direct docking supported
|
|
E3L005803
BDB005803
|
BDBM135290
CO[C@@H]1C[C@@H](CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C(C)[C@H]2CC[C@H](C)CC2)C1
|
C28H33ClFN7O3 570.069000 |
RXZDEKVLPHOLPC-OMONPXGRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135290
|
Local ready
Direct docking supported
|
|
E3L005804
BDB005804
|
BDBM135291
CO[C@@H]1C[C@@H](CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C(C)[C@H]2CC[C@H](C)CC2)C1
|
C28H33ClFN7O3 570.069000 |
RXZDEKVLPHOLPC-OMONPXGRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135291
|
Local ready
Direct docking supported
|
|
E3L005805
BDB005805
|
BDBM135292
CC(C)[C@@H]1C[C@@H](O)CN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C29H36ClN7O3 566.106000 |
YETFXBIXUYXZCC-WQMVJKRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135292
|
Local ready
Direct docking supported
|
|
E3L005806
BDB005806
|
BDBM135294
CO[C@@H]1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C(C)[C@H]2CC[C@H](C)CC2)C1
|
C28H34ClN7O3 552.079000 |
CRCYVDABEGRWRS-ZPTJUPFESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135294
|
Local ready
Direct docking supported
|
|
E3L005807
BDB005807
|
BDBM135295
CC([C@H]1CC[C@H](C)CC1)n1c(N2C[C@H](O)C[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
|
C27H32ClN7O3 538.052000 |
NNJDDNCVQBYTOS-ZTYJXQELSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135295
|
Local ready
Direct docking supported
|
|
E3L005808
BDB005808
|
BDBM135298
CC(=O)N1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C28H33ClN8O3 565.078000 |
UREBPUUDAYZIOZ-ZHALLVOQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135298
|
Local ready
Direct docking supported
|
|
E3L005809
BDB005809
|
BDBM135299
C[C@@H]1CN(C(=O)C2CC2)CCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C30H35ClN8O3 591.116000 |
IYPCCQZCPSITRD-GUDVDZBRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135299
|
Local ready
Direct docking supported
|
|
E3L005810
BDB005810
|
BDBM135300
C[C@@H]1CN(C(=O)C2CC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C31H37ClN8O3 605.143000 |
UDQZJTVYNZMLNM-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135300
|
Local ready
Direct docking supported
|
|
E3L005811
BDB005811
|
BDBM135302
C[C@@H]1CN(S(C)(=O)=O)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H35ClN8O4S 615.160000 |
NXMHOVMUSHDSGK-NCXUSEDFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135302
|
Local ready
Direct docking supported
|
|
E3L005812
BDB005812
|
BDBM135303
CCOC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C30H37ClN8O4 609.131000 |
GEOSOYWTTHGKKS-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135303
|
Local ready
Direct docking supported
|
|
E3L005813
BDB005813
|
BDBM135304
CCNC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C30H38ClN9O3 608.147000 |
NLDZHFIWUYXHBL-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135304
|
Local ready
Direct docking supported
|
|
E3L005814
BDB005814
|
BDBM135305
CCC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C30H37ClN8O3 593.132000 |
YEJOMGIETZPANP-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135305
|
Local ready
Direct docking supported
|
|
E3L005815
BDB005815
|
BDBM135306
C[C@@H]1CN(C(=O)C2CCC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C32H39ClN8O3 619.170000 |
FYRJMRGOAGVHDI-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135306
|
Local ready
Direct docking supported
|
|
E3L005816
BDB005816
|
BDBM135307
CCCC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C31H39ClN8O3 607.159000 |
BHGWNAYPLOZTOM-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135307
|
Local ready
Direct docking supported
|
|
E3L005817
BDB005817
|
BDBM135308
COC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C29H35ClN8O4 595.104000 |
SJERQOBZODKGGG-NCXUSEDFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135308
|
Local ready
Direct docking supported
|
|
E3L005818
BDB005818
|
BDBM135309
CC(C)OC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C31H39ClN8O4 623.158000 |
ADUYUWMIUJKVDB-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135309
|
Local ready
Direct docking supported
|
|
E3L005819
BDB005819
|
BDBM135310
CCCNC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C31H40ClN9O3 622.174000 |
WOQJMZYDIIIYTC-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135310
|
Local ready
Direct docking supported
|
|
E3L005820
BDB005820
|
BDBM135311
CC(C)NC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C31H40ClN9O3 622.174000 |
KBWDFMMOJXBZIN-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135311
|
Local ready
Direct docking supported
|