| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005781
BDB005781
|
BDBM135257
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccn3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C30H31ClN8O3 587.084000 |
JRXYOLKMVDSQEN-MHPIHPPYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135257
|
Local ready
Direct docking supported
|
|
E3L005782
BDB005782
|
BDBM135258
C[C@H]1CC[C@H](Cn2c(N3CCOC4CCOCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H32ClN7O4 566.062000 |
SGJLQDYORVVDHC-CFZVCUOASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135258
|
Local ready
Direct docking supported
|
|
E3L005783
BDB005783
|
BDBM135259
CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C2COCCC2O1
|
C29H34ClN7O4 580.089000 |
SYFZLLLVEXLINK-ORFRVJLPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135259
|
Local ready
Direct docking supported
|
|
E3L005784
BDB005784
|
BDBM135261
C[C@H]1CC[C@H](Cn2c(N3CCOC4COCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C27H30ClN7O4 552.035000 |
SAPPEHHVJFYKBB-BALZWMQLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135261
|
Local ready
Direct docking supported
|
|
E3L005785
BDB005785
|
BDBM135263
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CC(F)C[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H31ClFN7O3 568.053000 |
WTSWXJASTNOJKH-DCBGLIRBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135263
|
Local ready
Direct docking supported
|
|
E3L005786
BDB005786
|
BDBM135267
C[C@H]1CC[C@H](Cn2c(N3CCCOC4CCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C29H34ClN7O3 564.090000 |
KOYAFLZGKBWSGS-YTFADCBGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135267
|
Local ready
Direct docking supported
|
|
E3L005787
BDB005787
|
BDBM135269
CC1N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCOC1(C)C
|
C28H34ClN7O3 552.079000 |
RCAKHZDTMCXVCJ-KFZAHXERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135269
|
Local ready
Direct docking supported
|
|
E3L005788
BDB005788
|
BDBM135270
CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C2CCCCC2O1
|
C30H36ClN7O3 578.117000 |
VPDFQDKDHNSJBD-HXHGWAKHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135270
|
Local ready
Direct docking supported
|
|
E3L005789
BDB005789
|
BDBM135271
C[C@H]1CC[C@H](Cn2c(NCc3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H28ClN7O2 530.032000 |
VTEMVYUPWHHDRV-UAPYVXQJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135271
|
Local ready
Direct docking supported
|
|
E3L005790
BDB005790
|
BDBM135272
COCC(C)Nc1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H30ClN7O3 512.014000 |
IAENVRKCAAHONF-CMTYHBQSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135272
|
Local ready
Direct docking supported
|
|
E3L005791
BDB005791
|
BDBM135273
CN(Cc1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H30ClN7O2 544.059000 |
OGRAXFCJRLFZIH-KESTWPANSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135273
|
Local ready
Direct docking supported
|
|
E3L005792
BDB005792
|
BDBM135274
CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C2CCCC2O1
|
C29H34ClN7O3 564.090000 |
DWNONFRFFUGFCL-ORFRVJLPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135274
|
Local ready
Direct docking supported
|
|
E3L005793
BDB005793
|
BDBM135276
CC1CN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)[C@@H](C)O1
|
C28H34ClN7O3 552.079000 |
QHRZDBYDJMPDHU-MXOGIUDQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135276
|
Local ready
Direct docking supported
|
|
E3L005794
BDB005794
|
BDBM135278
COCC(C)N(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H32ClN7O3 526.041000 |
OBNXSCOIIUXZOD-XUWMOKQASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135278
|
Local ready
Direct docking supported
|
|
E3L005795
BDB005795
|
BDBM135279
C[C@H]1CC[C@H](Cn2c(Nc3ccccn3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C26H25ClN8O2 516.993000 |
JXVBMXCIEYPKRC-WKILWMFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135279
|
Local ready
Direct docking supported
|
|
E3L005796
BDB005796
|
BDBM135280
C[C@H]1CC[C@H](Cn2c(Nc3ccccn3)nc3cc(C(=O)O)nc(-c4cncc(Cl)c4)c32)CC1
|
C25H25ClN6O2 476.968000 |
DMTAIMXCXISIBF-WKILWMFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135280
|
Local ready
Direct docking supported
|
|
E3L005797
BDB005797
|
BDBM135281
CN(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H28ClN7O2 530.032000 |
IIUVSXBIHCNEBA-IYARVYRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135281
|
Local ready
Direct docking supported
|
|
E3L005798
BDB005798
|
BDBM135282
CN(c1ccccc1)c1nc2cc(C(=O)O)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H28ClN5O2 490.007000 |
SVWMSHZYKVHHNW-IYARVYRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135282
|
Local ready
Direct docking supported
|
|
E3L005799
BDB005799
|
BDBM135283
C[C@H]1CC[C@H](Cn2c(Nc3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C27H26ClN7O2 516.005000 |
FUFADZNLPYRNQX-QAQDUYKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135283
|
Local ready
Direct docking supported
|
|
E3L005800
BDB005800
|
BDBM135284
CC([C@H]1CC[C@H](C)CC1)n1c(N2CCO[C@@H]3CCC[C@H]32)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
|
C29H34ClN7O3 564.090000 |
DKACUGXPMJISHM-LPYVOSKBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135284
|
Local ready
Direct docking supported
|