| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005821
BDB005821
|
BDBM135312
CC(=O)N1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C(C)C1C
|
C29H35ClN8O3 579.105000 |
OOHXNUMHWLQNTL-ZXBJXWMASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135312
|
Local ready
Direct docking supported
|
|
E3L005822
BDB005822
|
BDBM135313
CC1C(C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCN1C(=O)C1CC1
|
C31H37ClN8O3 605.143000 |
NNMUYBHTDBUKTM-YUNKUFCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135313
|
Local ready
Direct docking supported
|
|
E3L005823
BDB005823
|
BDBM135314
CC(C)C(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C31H39ClN8O3 607.159000 |
VZYMESXWHUJQTO-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135314
|
Local ready
Direct docking supported
|
|
E3L005824
BDB005824
|
BDBM135315
C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C4CC4)[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C32H37ClN8O3 617.154000 |
FLGGPSBSBAEAHH-YYMWKTKSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135315
|
Local ready
Direct docking supported
|
|
E3L005825
BDB005825
|
BDBM135316
CC(=O)N1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]2CCC[C@H]21
|
C30H35ClN8O3 591.116000 |
WOYIJXYJHLMGBZ-WBAYHMBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135316
|
Local ready
Direct docking supported
|
|
E3L005826
BDB005826
|
BDBM135317
C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C(F)F)[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C30H33ClF2N8O3 627.096000 |
NBHFLQPGNMCLPE-IEGYKGNPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135317
|
Local ready
Direct docking supported
|
|
E3L005827
BDB005827
|
BDBM135318
C[C@H]1CC[C@H](Cn2c(N3CCN(C(=O)C4CCC4)[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C33H39ClN8O3 631.181000 |
UVQXWVUZWYNNES-GEFNZCRYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135318
|
Local ready
Direct docking supported
|
|
E3L005828
BDB005828
|
BDBM135319
C[C@@H]1CN(C(=O)N(C)C)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C30H38ClN9O3 608.147000 |
GSHMRLPMONLJHD-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135319
|
Local ready
Direct docking supported
|
|
E3L005829
BDB005829
|
BDBM135320
CCN(C)C(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C31H40ClN9O3 622.174000 |
UODZQKJQOMHEBS-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135320
|
Local ready
Direct docking supported
|
|
E3L005830
BDB005830
|
BDBM135321
C[C@@H]1CN(C(=O)C2(F)CC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C31H36ClFN8O3 623.133000 |
OJVAPDGKEUAJAO-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135321
|
Local ready
Direct docking supported
|
|
E3L005831
BDB005831
|
BDBM135322
C[C@@H]1CN(C(=O)C2CC2(F)F)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C31H35ClF2N8O3 641.123000 |
QREKUZOWNHUVEC-SWHXLWHISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135322
|
Local ready
Direct docking supported
|
|
E3L005832
BDB005832
|
BDBM135323
C[C@@H]1CN(C(=O)C(F)F)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H33ClF2N8O3 615.085000 |
VFRUMQCFIQTLMB-BRSBDYLESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135323
|
Local ready
Direct docking supported
|
|
E3L005833
BDB005833
|
BDBM135324
C[C@@H]1CN(C(=O)C2(C)COC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C32H39ClN8O4 635.169000 |
PEWHIEOVWHYESN-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135324
|
Local ready
Direct docking supported
|
|
E3L005834
BDB005834
|
BDBM135325
C[C@@H]1CN(C(=O)C2(C)CC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C32H39ClN8O3 619.170000 |
AGSLKWCGDBAKGB-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135325
|
Local ready
Direct docking supported
|
|
E3L005835
BDB005835
|
BDBM135326
C[C@@H]1CN(C(=O)C2COC2)C[C@@H](C)N1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C31H37ClN8O4 621.142000 |
GZHNAJYYLQVOBI-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135326
|
Local ready
Direct docking supported
|
|
E3L005836
BDB005836
|
BDBM135327
COCC(=O)N1C[C@@H](C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C30H37ClN8O4 609.131000 |
KJOPZPVDBZICNN-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135327
|
Local ready
Direct docking supported
|
|
E3L005837
BDB005837
|
BDBM135328
CCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
|
C29H35ClN6O3 551.091000 |
CXWKNIIYDYRVLK-XYCFSGNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135328
|
Local ready
Direct docking supported
|
|
E3L005838
BDB005838
|
BDBM135330
CCOC(c1nc2cc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
|
C29H35ClN6O3 551.091000 |
GYUWRFCECFASOX-XYCFSGNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135330
|
Local ready
Direct docking supported
|
|
E3L005839
BDB005839
|
BDBM135332
CCOC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H29ClN6O3 496.999000 |
GHUWMTUBKVOLEE-CMTYHBQSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135332
|
Local ready
Direct docking supported
|
|
E3L005840
BDB005840
|
BDBM135334
CCOC(CC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O3 511.026000 |
LXDQDKZWFQSCGI-CZEDARRBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135334
|
Local ready
Direct docking supported
|