| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005881
BDB005881
|
BDBM135398
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3c(F)c(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H31ClFN7O3 568.053000 |
IZMACIODMJFJRV-XNFNUYLZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135398
|
Local ready
Direct docking supported
|
|
E3L005882
BDB005882
|
BDBM135399
COc1c(-c2noc(=O)[nH]2)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@@H]3CCC[C@H]31)n2C[C@H]1CC[C@H](C)CC1
|
C29H34ClN7O4 580.089000 |
IUMHJKWIWSUJIH-DEPWHIHDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135399
|
Local ready
Direct docking supported
|
|
E3L005883
BDB005883
|
BDBM135400
Cc1c(-c2noc(=O)[nH]2)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@@H]3CCC[C@H]31)n2C[C@H]1CC[C@H](C)CC1
|
C29H34ClN7O3 564.090000 |
UITXZAZIVADQIR-LVOPCWDJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135400
|
Local ready
Direct docking supported
|
|
E3L005884
BDB005884
|
BDBM135401
CN(C)c1c(C(=O)O)nc(-c2cncc(Cl)c2)c2c1nc(N1CCO[C@@H]3CCC[C@H]31)n2C[C@H]1CC[C@H](C)CC1
|
C29H37ClN6O3 553.107000 |
FRMLMWRFFZHYID-MCEIDBOGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135401
|
Local ready
Direct docking supported
|
|
E3L005885
BDB005885
|
BDBM135402
COCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O3 511.026000 |
BOHJWRUCGNOBMS-GQRAJKLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135402
|
Local ready
Direct docking supported
|
|
E3L005886
BDB005886
|
BDBM135403
COCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O3 511.026000 |
BOHJWRUCGNOBMS-GQRAJKLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135403
|
Local ready
Direct docking supported
|
|
E3L005887
BDB005887
|
BDBM135404
COCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O3 511.026000 |
BOHJWRUCGNOBMS-GQRAJKLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135404
|
Local ready
Direct docking supported
|
|
E3L005888
BDB005888
|
BDBM135405
COCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O3 511.026000 |
BOHJWRUCGNOBMS-GQRAJKLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135405
|
Local ready
Direct docking supported
|
|
E3L005889
BDB005889
|
BDBM135406
CS(=O)(=O)NC(=O)c1cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C28H35ClN6O4S 587.146000 |
FOVGPBPSNKEHGH-MCJPXMOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135406
|
Local ready
Direct docking supported
|
|
E3L005890
BDB005890
|
BDBM135407
CN(C)S(=O)(=O)NC(=O)c1cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C29H38ClN7O4S 616.188000 |
IADFONFJBQGQSB-PIYXRGFCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135407
|
Local ready
Direct docking supported
|
|
E3L005891
BDB005891
|
BDBM135408
CNC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C31H35ClN6O2 559.114000 |
WQQBXFMMYBXVRZ-IZVMNLJQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135408
|
Local ready
Direct docking supported
|
|
E3L005892
BDB005892
|
BDBM135409
CN(C)C(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C32H37ClN6O2 573.141000 |
SPEKTYMVGNZTAL-VPYPWEPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135409
|
Local ready
Direct docking supported
|
|
E3L005893
BDB005893
|
BDBM135410
CS(=O)(=O)Nc1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C30H35ClN6O3S 595.169000 |
JAZIYSMLAMDBQY-WOVHNISZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135410
|
Local ready
Direct docking supported
|
|
E3L005894
BDB005894
|
BDBM135411
C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)(F)F)nc3cc(-c4nnn[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C25H27ClF3N9 546.001000 |
LXGNSQRNDPXXEN-AVYPCKFXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135411
|
Local ready
Direct docking supported
|
|
E3L005895
BDB005895
|
BDBM135412
Cn1[nH]c(-c2cc3nc(N4CCC[C@H]4CF)n(C[C@H]4CC[C@H](C)CC4)c3c(-c3cncc(Cl)c3)n2)nc1=O
|
C27H32ClFN8O 539.059000 |
SBGYEFPPMMJYBQ-ZWOKBUDYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135412
|
Local ready
Direct docking supported
|
|
E3L005896
BDB005896
|
BDBM135413
C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3CF)nc3cc(-c4n[nH]c(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C26H30ClFN8O 525.032000 |
BKANZFXGMQIDPN-BXWFABGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135413
|
Local ready
Direct docking supported
|
|
E3L005897
BDB005897
|
BDBM135414
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4nnn[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C27H32ClN9O 534.068000 |
PZTUOKVCYNWBOF-IEGYKGNPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135414
|
Local ready
Direct docking supported
|
|
E3L005898
BDB005898
|
BDBM135415
COC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C31H34ClN5O3 560.098000 |
SYNFYBFKFDFYHY-IZVMNLJQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135415
|
Local ready
Direct docking supported
|
|
E3L005899
BDB005899
|
BDBM135416
CCOC(=O)c1cc2nc(N3CCOC[C@H]3c3ccccc3)n(CC3CCC(C)CC3)c2c(-c2cncc(Cl)c2)n1
|
C32H36ClN5O3 574.125000 |
FNAMBLUKCRUASU-HVKFLMNHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135416; PubChem:CID90235849
|
Local ready
Direct docking supported
|
|
E3L005900
BDB005900
|
BDBM135417
CCON(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1)C1CC1
|
C27H32ClN7O3 538.052000 |
ZSUPCYDBQJNTGJ-XUWMOKQASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135417
|
Local ready
Direct docking supported
|