| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005921
BDB005921
|
BDBM135441
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)c[nH]c4=O)c32)CC1
|
C28H32ClN7O4 566.062000 |
NSWPYAAQKVMFRO-AHWCRGGASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135441
|
Local ready
Direct docking supported
|
|
E3L005922
BDB005922
|
BDBM135442
Cc1cncc(-c2nc(-c3noc(=O)[nH]3)cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C29H35N7O3 529.645000 |
FFXICAYCOJFMTL-IBPUDULPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135442
|
Local ready
Direct docking supported
|
|
E3L005923
BDB005923
|
BDBM135443
Cc1cncc(-c2nc(-c3noc(=O)[nH]3)cc3nc(N4CCO[C@H]5CCC[C@@H]54)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C29H35N7O3 529.645000 |
FFXICAYCOJFMTL-NZUPQLOKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135443
|
Local ready
Direct docking supported
|
|
E3L005924
BDB005924
|
BDBM135444
CNc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C29H35ClN8O3 579.105000 |
PJRCGOQWVKPRSN-IEGYKGNPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135444
|
Local ready
Direct docking supported
|
|
E3L005925
BDB005925
|
BDBM135445
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)c[nH]c4=O)c32)CC1
|
C31H32ClN7O4 602.095000 |
XBVDIYGNYLXXEQ-MHPIHPPYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135445
|
Local ready
Direct docking supported
|
|
E3L005926
BDB005926
|
BDBM135446
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncnc4)c32)CC1
|
C30H32N8O3 552.639000 |
BUPLVKXWFMJCOY-RLSLOFABSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135446
|
Local ready
Direct docking supported
|
|
E3L005927
BDB005927
|
BDBM135447
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cnccn4)c32)CC1
|
C30H32N8O3 552.639000 |
BECKWCAEIKBNTE-RLSLOFABSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135447
|
Local ready
Direct docking supported
|
|
E3L005928
BDB005928
|
BDBM135448
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4ccnnc4)c32)CC1
|
C30H32N8O3 552.639000 |
UUGKETZUKLYNCG-RLSLOFABSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135448
|
Local ready
Direct docking supported
|
|
E3L005929
BDB005929
|
BDBM135449
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cccnn4)c32)CC1
|
C30H32N8O3 552.639000 |
KKBSJDLRVGVTLG-RLSLOFABSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135449
|
Local ready
Direct docking supported
|
|
E3L005930
BDB005930
|
BDBM135450
CSCC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H29ClN6O2S 513.067000 |
FIVGIHBWZXQDOL-CMTYHBQSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135450
|
Local ready
Direct docking supported
|
|
E3L005931
BDB005931
|
BDBM135451
CC(CS(C)(=O)=O)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H29ClN6O4S 545.065000 |
OYAUWOFNPITSPO-CMTYHBQSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135451
|
Local ready
Direct docking supported
|
|
E3L005932
BDB005932
|
BDBM135452
CCC(CSC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O2S 527.094000 |
KXXXPZUZYQGPAT-BDWYFLKXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135452
|
Local ready
Direct docking supported
|
|
E3L005933
BDB005933
|
BDBM135453
CCC(CS(C)(=O)=O)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O4S 559.092000 |
AROHMTKSOGZKIM-BDWYFLKXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135453
|
Local ready
Direct docking supported
|
|
E3L005934
BDB005934
|
BDBM135454
CC(C)C(CS(C)(=O)=O)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H33ClN6O4S 573.119000 |
GHQZUCCFJMRYSJ-IWZNKUOBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135454
|
Local ready
Direct docking supported
|
|
E3L005935
BDB005935
|
BDBM135455
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(C4CC=CC(=O)N4)nc(-c4cncc(Cl)c4)c32)CC1
|
C34H37ClN6O2 597.163000 |
YKAZCHMHDWOTRW-VZKWARJPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135455
|
Local ready
Direct docking supported
|
|
E3L005936
BDB005936
|
BDBM135456
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3cc(-c4noc(=O)[nH]4)nc(OCC4CCC4)c32)CC1
|
C31H38N6O4 558.683000 |
LMQKCHNSCFGQFF-WOVHNISZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135456
|
Local ready
Direct docking supported
|
|
E3L005937
BDB005937
|
BDBM135457
CC(Oc1nc(-c2noc(=O)[nH]2)cc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H40N6O4 572.710000 |
ZDCGAFWPICMALP-LFAJDQHLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135457
|
Local ready
Direct docking supported
|
|
E3L005938
BDB005938
|
BDBM135812
CCn1c(=O)c2cnc3c(Cl)cccc3c2n(C2CCCC2)c1=O
|
C18H18ClN3O2 343.814000 |
RNTPXDNXVJTNNP-UHFFFAOYSA-N | Q99732 | Lipopolysaccharide-induced tumor necrosis factor-alpha factor |
BindingDB, PubChem
BindingDB:BDBM135812; PubChem:CID58329477
|
Local ready
Direct docking supported
|
|
E3L005939
BDB005939
|
BDBM135813
CCCc1cccc2c1ncc1c(=O)n(CC)c(=O)n(C3CCCC3)c12
|
C21H25N3O2 351.450000 |
IAIFPELWEXGBKC-UHFFFAOYSA-N | Q99732 | Lipopolysaccharide-induced tumor necrosis factor-alpha factor |
BindingDB, PubChem
BindingDB:BDBM135813; PubChem:CID58329390
|
Local ready
Direct docking supported
|
|
E3L005940
BDB005940
|
BDBM135814
CCn1c(=O)c2cnc3c(C(C)C)cccc3c2n(C2CCCC2)c1=O
|
C21H25N3O2 351.450000 |
IWWGJHDCEUWDTE-UHFFFAOYSA-N | Q99732 | Lipopolysaccharide-induced tumor necrosis factor-alpha factor |
BindingDB, PubChem
BindingDB:BDBM135814; PubChem:CID58329430
|
Local ready
Direct docking supported
|