| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005901
BDB005901
|
BDBM135418
CCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1)C1CC1
|
C28H33ClN6O3 537.064000 |
PJGMHURMTNPVFZ-RNFMHXQYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135418
|
Local ready
Direct docking supported
|
|
E3L005902
BDB005902
|
BDBM135419
CCOC(c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1)C1CC1
|
C28H33ClN6O3 537.064000 |
PJGMHURMTNPVFZ-RNFMHXQYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135419
|
Local ready
Direct docking supported
|
|
E3L005903
BDB005903
|
BDBM135421
CCOC(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C26H31ClN6O3 511.026000 |
DQEAMAGOZZSBEV-GQRAJKLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135421
|
Local ready
Direct docking supported
|
|
E3L005904
BDB005904
|
BDBM135423
CCOC(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C27H33ClN6O4 541.052000 |
XEXOJNYQMHVNNX-KSUCGMBASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135423
|
Local ready
Direct docking supported
|
|
E3L005905
BDB005905
|
BDBM135424
CCON(COC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C(C)[C@H]1CC[C@H](C)CC1
|
C26H32ClN7O4 542.040000 |
AQPWEKIFXPEUBY-XUWMOKQASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135424
|
Local ready
Direct docking supported
|
|
E3L005906
BDB005906
|
BDBM135425
CC([C@H]1CC[C@H](C)CC1)n1c(N2CCN(C(=O)C3(F)CC3)C[C@H]2C)nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c21
|
C31H36ClFN8O3 623.133000 |
HKXVEJYALGEOSJ-LAURYZNVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135425
|
Local ready
Direct docking supported
|
|
E3L005907
BDB005907
|
BDBM135426
O=c1[nH]c(-c2cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(Cc4ccc(C(F)(F)F)cc4)c3c(-c3cncc(Cl)c3)n2)no1
|
C28H23ClF3N7O3 597.985000 |
BRSDRQCFISXLFK-FGZHOGPDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135426
|
Local ready
Direct docking supported
|
|
E3L005908
BDB005908
|
BDBM135427
CC[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C29H34ClN7O3 564.090000 |
DOLNTHQVJXBLGG-MCJPXMOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135427
|
Local ready
Direct docking supported
|
|
E3L005909
BDB005909
|
BDBM135428
CC[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C29H34ClN7O3 564.090000 |
QLEFQJWVYUDTEZ-MCJPXMOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135428
|
Local ready
Direct docking supported
|
|
E3L005910
BDB005910
|
BDBM135429
O=c1[nH]c(-c2cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(Cc4ccc(C(F)(F)F)c(F)c4)c3c(-c3cncc(Cl)c3)n2)no1
|
C28H22ClF4N7O3 615.975000 |
GLSFBVTZAQYFPB-FGZHOGPDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135429
|
Local ready
Direct docking supported
|
|
E3L005911
BDB005911
|
BDBM135431
O=c1[nH]c(-c2cc3nc(N4CCO[C@@H]5CCC[C@H]54)n(C[C@H]4CC[C@H](C(F)(F)F)CC4)c3c(-c3cncc(Cl)c3)n2)no1
|
C28H29ClF3N7O3 604.033000 |
MMEFJGFDEDSQQY-PVFUSPOPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135431
|
Local ready
Direct docking supported
|
|
E3L005912
BDB005912
|
BDBM135432
CCC1CCC(Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)C1
|
C28H32ClN7O3 550.063000 |
ZOUXNVYMQAYQQO-OGRPUPFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135432
|
Local ready
Direct docking supported
|
|
E3L005913
BDB005913
|
BDBM135433
CN(C)c1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C30H37ClN8O3 593.132000 |
ZLAYKNIOGIYMRA-MCJPXMOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135433
|
Local ready
Direct docking supported
|
|
E3L005914
BDB005914
|
BDBM135434
Cc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C29H34ClN7O3 564.090000 |
GCUZIVVOLGZZOV-KVOAMPFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135434
|
Local ready
Direct docking supported
|
|
E3L005915
BDB005915
|
BDBM135435
Cc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C29H34ClN7O3 564.090000 |
GCUZIVVOLGZZOV-XNDUBXFTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135435
|
Local ready
Direct docking supported
|
|
E3L005916
BDB005916
|
BDBM135436
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)cnc4OCCO)c32)CC1
|
C30H36ClN7O5 610.115000 |
GRRITGHUYFGRFS-MCJPXMOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135436
|
Local ready
Direct docking supported
|
|
E3L005917
BDB005917
|
BDBM135437
COc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C29H34ClN7O4 580.089000 |
RQLXAFSVYOPPMY-DODAUVCRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135437
|
Local ready
Direct docking supported
|
|
E3L005918
BDB005918
|
BDBM135438
COc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C29H34ClN7O4 580.089000 |
RQLXAFSVYOPPMY-IEGYKGNPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135438
|
Local ready
Direct docking supported
|
|
E3L005919
BDB005919
|
BDBM135439
COCCOc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@@H]4CCC[C@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C31H38ClN7O5 624.142000 |
XGEMHWFPYIHYMV-PIYXRGFCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135439
|
Local ready
Direct docking supported
|
|
E3L005920
BDB005920
|
BDBM135440
COCCOc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)cc2nc(N3CCO[C@H]4CCC[C@@H]43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C31H38ClN7O5 624.142000 |
XGEMHWFPYIHYMV-CWGXUGAXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM135440
|
Local ready
Direct docking supported
|