| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005961
BDB005961
|
BDBM135929
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N(C(C)=O)C3CCOCC3)CC1)C(=O)C2
|
C32H41ClN2O5 569.142000 |
KOCISMZSDGPGDO-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135929; PubChem:CID71145874
|
Local ready
Direct docking supported
|
|
E3L005962
BDB005962
|
BDBM135930
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(N(CCCO)C(C)=O)CC1)C(=O)C2
|
C30H39ClN2O5 543.104000 |
TXQHPLXXTHRHRP-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM135930; PubChem:CID71145855
|
Local ready
Direct docking supported
|
|
E3L005963
BDB005963
|
BDBM135931
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)=O)CC1)C(=O)C2
|
C27H32ClNO4 470.009000 |
JSYUFMRMPYXXDZ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135931; PubChem:CID71145828
|
Local ready
Direct docking supported
|
|
E3L005964
BDB005964
|
BDBM135932
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(C)O)CC1)C(=O)C2
|
C28H36ClNO4 486.052000 |
SIHFKJRRMJZERL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135932; PubChem:CID71145623
|
Local ready
Direct docking supported
|
|
E3L005965
BDB005965
|
BDBM135933
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(O)C3CCOCC3)CC1)C(=O)C2
|
C31H40ClNO5 542.116000 |
ZKJZNJOLPMJKMR-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM135933; PubChem:CID71145919
|
Local ready
Direct docking supported
|
|
E3L005966
BDB005966
|
BDBM135934
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(=O)C3CCOCC3)CC1)C(=O)C2
|
C31H38ClNO5 540.100000 |
ULFMQCWOJYGSHM-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM135934; PubChem:CID71145442
|
Local ready
Direct docking supported
|
|
E3L005967
BDB005967
|
BDBM135935
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(C1CCC(C(=O)C3CCOCC3)CC1)C(=O)C2
|
C31H38ClNO5 540.100000 |
ULFMQCWOJYGSHM-VDHQHCSHSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135935; PubChem:CID71145399
|
Local ready
Direct docking supported
|
|
E3L005968
BDB005968
|
BDBM135936
COc1cc2c(cc1OC(C)C)[C@@H](c1ccc(Cl)cc1)N(C1CCC(C(=O)C3CCOCC3)CC1)C(=O)C2
|
C31H38ClNO5 540.100000 |
ULFMQCWOJYGSHM-VDOBOPNRSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM135936; PubChem:CID71145550
|
Local ready
Direct docking supported
|
|
E3L005969
BDB005969
|
BDBM135937
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)C3CCOCC3)CC1)C(=O)C2
|
C32H42ClNO5 556.143000 |
REAPGKBAMYKPTR-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM135937; PubChem:CID71145769
|
Local ready
Direct docking supported
|
|
E3L005970
BDB005970
|
BDBM135938
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(C1CCC([C@@](C)(O)C3CCOCC3)CC1)C(=O)C2
|
C32H42ClNO5 556.143000 |
REAPGKBAMYKPTR-CSNHGWCUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135938; PubChem:CID71145579
|
Local ready
Direct docking supported
|
|
E3L005971
BDB005971
|
BDBM135939
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(C1CCC([C@](C)(O)C3CCOCC3)CC1)C(=O)C2
|
C32H42ClNO5 556.143000 |
REAPGKBAMYKPTR-VFFDEHEASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135939; PubChem:CID71145920
|
Local ready
Direct docking supported
|
|
E3L005972
BDB005972
|
BDBM135940
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(O)c3cccc(F)c3)CC1)C(=O)C2
|
C32H35ClFNO4 552.086000 |
CAAYSKRGLOUQCW-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135940; PubChem:CID71145850
|
Local ready
Direct docking supported
|
|
E3L005973
BDB005973
|
BDBM135941
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(=O)c3cccc(F)c3)CC1)C(=O)C2
|
C32H33ClFNO4 550.070000 |
GSWUIWAXXUDUPZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135941; PubChem:CID71145449
|
Local ready
Direct docking supported
|
|
E3L005974
BDB005974
|
BDBM135942
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)c3cccc(F)c3)CC1)C(=O)C2
|
C33H37ClFNO4 566.113000 |
PTAMYJBIGIABIM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135942; PubChem:CID71145384
|
Local ready
Direct docking supported
|
|
E3L005975
BDB005975
|
BDBM135943
CCC(O)(c1cccc(F)c1)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
|
C34H39ClFNO4 580.140000 |
VQPLOUWRQXWRQX-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM135943; PubChem:CID71145770
|
Local ready
Direct docking supported
|
|
E3L005976
BDB005976
|
BDBM135944
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)CC(C)C)CC1)C(=O)C2
|
C31H42ClNO4 528.133000 |
HPGSYGVHUBYWPN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135944; PubChem:CID71145886
|
Local ready
Direct docking supported
|
|
E3L005977
BDB005977
|
BDBM135945
CCCCC(C)(O)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1
|
C31H42ClNO4 528.133000 |
DQUIDHIGYCDUAW-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM135945; PubChem:CID71145605
|
Local ready
Direct docking supported
|
|
E3L005978
BDB005978
|
BDBM135946
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)CCC(C)C)CC1)C(=O)C2
|
C32H44ClNO4 542.160000 |
RZYJZQGRZQCZFW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135946; PubChem:CID71145875
|
Local ready
Direct docking supported
|
|
E3L005979
BDB005979
|
BDBM135947
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)c3ccoc3)CC1)C(=O)C2
|
C31H36ClNO5 538.084000 |
MUHLETNNWVCIER-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM135947; PubChem:CID71145740
|
Local ready
Direct docking supported
|
|
E3L005980
BDB005980
|
BDBM138298
NC(=O)c1cccc2c1C(=O)N(C1CCN(C3CCC(F)(F)CC3)CC1)C2
|
C20H25F2N3O2 377.435000 |
UYRWBJIRLVJAMX-UHFFFAOYSA-N | P09874 | Poly [ADP-ribose] polymerase 1 |
BindingDB, PubChem
BindingDB:BDBM138298; PubChem:CID50943015
|
Local ready
Direct docking supported
|