| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006121
BDB006121
|
BDBM143345
CCN1CCN(CCn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)C1=O
|
C27H28Cl2FN5O2 544.458000 |
KAKMQHCSBWFALW-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143345; PubChem:CID71585687
|
Local ready
Direct docking supported
|
|
E3L006122
BDB006122
|
BDBM143347
Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C(=O)OC(C)(C)C)C3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C31H36Cl2N4O3 583.560000 |
ODOZCWBAEOCSHE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143347; PubChem:CID71585783
|
Local ready
Direct docking supported
|
|
E3L006123
BDB006123
|
BDBM143348
Cc1cc(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)n(C)n1
|
C26H24Cl2FN5O 512.416000 |
HMYIFNWAXFJNOP-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143348; PubChem:CID89601894
|
Local ready
Direct docking supported
|
|
E3L006124
BDB006124
|
BDBM143349
CC(C)c1c2c(nn1Cc1ncc[nH]1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
|
C24H20Cl2FN5O 484.362000 |
ZYNISQAUMBGSTJ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143349; PubChem:CID71585785
|
Local ready
Direct docking supported
|
|
E3L006125
BDB006125
|
BDBM143350
CC(C)c1c2c(nn1Cc1nnn[nH]1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
|
C22H18Cl2FN7O 486.338000 |
IDNGXAWKJBFVGN-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143350; PubChem:CID71585786
|
Local ready
Direct docking supported
|
|
E3L006126
BDB006126
|
BDBM143353
Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCC(O)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C29H32Cl2N4O3 555.506000 |
IIZXQQZRRXYLSE-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143353; PubChem:CID71585880
|
Local ready
Direct docking supported
|
|
E3L006127
BDB006127
|
BDBM143356
Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCC(CCO)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C31H36Cl2N4O3 583.560000 |
VPQHGGCCSNCLAC-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143356; PubChem:CID71585881
|
Local ready
Direct docking supported
|
|
E3L006128
BDB006128
|
BDBM143357
CC(=O)N1CCC(NC(=O)Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
|
C31H35Cl2N5O3 596.559000 |
YMJKZOBXPAXXLG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143357; PubChem:CID71585882
|
Local ready
Direct docking supported
|
|
E3L006129
BDB006129
|
BDBM143360
CC(=O)N1CCN(C(=O)Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
|
C30H33Cl2N5O3 582.532000 |
YBBQYZSRNHSUCI-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143360; PubChem:CID71585883
|
Local ready
Direct docking supported
|
|
E3L006130
BDB006130
|
BDBM143363
Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCNC(=O)C3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C28H29Cl2N5O3 554.478000 |
DBEMYIHLOZGDDF-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143363; PubChem:CID71585884
|
Local ready
Direct docking supported
|
|
E3L006131
BDB006131
|
BDBM143364
Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCN(C)C(=O)C3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C29H31Cl2N5O3 568.505000 |
NNACMWCOVURKHA-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143364; PubChem:CID71585978
|
Local ready
Direct docking supported
|
|
E3L006132
BDB006132
|
BDBM143365
CC(=O)N1CCC(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
|
C30H34Cl2N4O2 553.534000 |
QZPHTHGRGSOROE-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143365; PubChem:CID71585979
|
Local ready
Direct docking supported
|
|
E3L006133
BDB006133
|
BDBM143369
Cc1cc(Cl)ccc1C1c2c(nn(CC3CCN(C(=O)NC(C)C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C32H39Cl2N5O2 596.603000 |
PSBHMQFAIJWIBA-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143369; PubChem:CID89602070
|
Local ready
Direct docking supported
|
|
E3L006134
BDB006134
|
BDBM143370
C=CCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C25H25Cl2N3O 454.401000 |
LTJSYZDDRJKJIO-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143370; PubChem:CID71585980
|
Local ready
Direct docking supported
|
|
E3L006135
BDB006135
|
BDBM143371
Cc1cc(Cl)ccc1C1c2c(nn(CC(O)CO)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C25H27Cl2N3O3 488.415000 |
HWOBQJWTOBDSQY-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143371; PubChem:CID71585981
|
Local ready
Direct docking supported
|
|
E3L006136
BDB006136
|
BDBM143372
CC(=O)N1CCC(O)(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)CC1
|
C30H34Cl2N4O3 569.533000 |
DZWXCJZDTKKTNU-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143372; PubChem:CID71585982
|
Local ready
Direct docking supported
|
|
E3L006137
BDB006137
|
BDBM143376
Cc1cc(Cl)ccc1C1c2c(nn(CC3(O)CCN(C(=O)NC(C)C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C32H39Cl2N5O3 612.602000 |
CILSJFJSUMUUSU-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM143376
|
Local ready
Direct docking supported
|
|
E3L006138
BDB006138
|
BDBM143377
Cc1cc(Cl)ccc1C1c2c(nn(CCc3ccccc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C29H26Cl2FN3O 522.451000 |
BUOAGPCDZLSTGG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143377; PubChem:CID71586077
|
Local ready
Direct docking supported
|
|
E3L006139
BDB006139
|
BDBM143378
Cc1cc(Cl)ccc1C1c2c(nn(CCN(C)C)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C25H27Cl2FN4O 489.422000 |
PKOHPVVUDUZROD-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143378; PubChem:CID71586078
|
Local ready
Direct docking supported
|
|
E3L006140
BDB006140
|
BDBM143379
CC(C)c1c2c(nn1Cc1ccccc1C#N)C(=O)N(c1ccc(F)c(F)c1)C2c1ccc(Cl)cc1
|
C28H21ClF2N4O 502.952000 |
KQFUYAPAPGFYMI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143379; PubChem:CID71586079
|
Local ready
Direct docking supported
|