| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006141
BDB006141
|
BDBM143380
Cc1nc(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cccc(Cl)c2F)C3=O)cs1
|
C26H23Cl2FN4OS 529.468000 |
GKYIFSPUMLSNRN-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143380; PubChem:CID71586080
|
Local ready
Direct docking supported
|
|
E3L006142
BDB006142
|
BDBM143381
COCCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
|
C24H24Cl2FN3O2 476.379000 |
PUYWZQFYSPULBD-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143381; PubChem:CID71586174
|
Local ready
Direct docking supported
|
|
E3L006143
BDB006143
|
BDBM143382
Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccncc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C27H23Cl2FN4O 509.412000 |
WZEXNVKJEUXBLY-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143382; PubChem:CID71586175
|
Local ready
Direct docking supported
|
|
E3L006144
BDB006144
|
BDBM143383
Cc1cc(Cl)ccc1C1c2c(nn(Cc3cscn3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C25H21Cl2FN4OS 515.441000 |
GUUCXMISBBUFFH-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143383; PubChem:CID71586176
|
Local ready
Direct docking supported
|
|
E3L006145
BDB006145
|
BDBM143384
COCCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C25H27Cl2N3O2 472.416000 |
VWMHDGDJQMBFHU-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143384; PubChem:CID71586177
|
Local ready
Direct docking supported
|
|
E3L006146
BDB006146
|
BDBM143385
Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccccn3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C28H26Cl2N4O 505.449000 |
PSCSHVNMQAGNHC-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143385; PubChem:CID71586178
|
Local ready
Direct docking supported
|
|
E3L006147
BDB006147
|
BDBM143386
CNC(=O)Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
|
C24H23Cl2FN4O2 489.378000 |
YEQFUJXHFVNFLD-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143386; PubChem:CID71586275
|
Local ready
Direct docking supported
|
|
E3L006148
BDB006148
|
BDBM143389
Cc1cc(Cl)ccc1C1c2c(nn(CCC(C)C)c2C2CC2)C(=O)N1c1cccc(Cl)c1F
|
C26H26Cl2FN3O 486.418000 |
FRXDUXKRQHHRRK-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143389; PubChem:CID71586276
|
Local ready
Direct docking supported
|
|
E3L006149
BDB006149
|
BDBM143390
Cc1cc(Cl)ccc1C1c2c(nn(CCCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C24H24Cl2FN3O2 476.379000 |
WHEPFCCOZIXFLC-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143390; PubChem:CID71586277
|
Local ready
Direct docking supported
|
|
E3L006150
BDB006150
|
BDBM143392
Cc1cc(Cl)ccc1C1c2c(nn(CC(=O)N3CCCC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C28H30Cl2N4O2 525.480000 |
IVOGMBDXHMRJFP-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143392; PubChem:CID71586279
|
Local ready
Direct docking supported
|
|
E3L006151
BDB006151
|
BDBM143393
Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCO3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C27H29Cl2N3O2 498.454000 |
KZKVSNXVFALSMC-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143393; PubChem:CID71586278
|
Local ready
Direct docking supported
|
|
E3L006152
BDB006152
|
BDBM143394
Cc1cc(Cl)ccc1C1c2c(nn(CCN3CCN(C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C29H35Cl2N5O 540.539000 |
UNZCOOAPYFTFKR-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143394; PubChem:CID71586366
|
Local ready
Direct docking supported
|
|
E3L006153
BDB006153
|
BDBM143395
Cc1cc(Cl)ccc1C1c2c(nn(CC(C)(C)O)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C25H26Cl2FN3O2 490.406000 |
WMPSGRIFZXRFEB-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143395; PubChem:CID71586367
|
Local ready
Direct docking supported
|
|
E3L006154
BDB006154
|
BDBM143396
CCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
|
C27H32Cl2N4O2 515.485000 |
ZYJZAJSSCZJWTL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143396; PubChem:CID71586368
|
Local ready
Direct docking supported
|
|
E3L006155
BDB006155
|
BDBM143397
Cc1cc(Cl)ccc1C1c2c(nn(CCN3CCCC3=O)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C28H30Cl2N4O2 525.480000 |
IRWCMXNZTJROFT-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143397; PubChem:CID71586369
|
Local ready
Direct docking supported
|
|
E3L006156
BDB006156
|
BDBM143398
Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccccc3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C29H27Cl2N3O 504.461000 |
AVTJOXSIUYDNFU-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143398; PubChem:CID71586370
|
Local ready
Direct docking supported
|
|
E3L006157
BDB006157
|
BDBM143399
Cc1cc(Cl)ccc1C1c2c(nn(C(=O)N3CCN(C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C28H31Cl2N5O2 540.495000 |
MVJPAODGJWVCNG-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143399; PubChem:CID71585478
|
Local ready
Direct docking supported
|
|
E3L006158
BDB006158
|
BDBM143400
Cc1cc(Cl)ccc1C1c2c(nn(C(=O)N(C)c3ccccc3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C30H28Cl2N4O2 547.486000 |
YDPLGSFJBCHSDW-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143400; PubChem:CID71586458
|
Local ready
Direct docking supported
|
|
E3L006159
BDB006159
|
BDBM143401
COC(=O)N1CCCC1Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H32Cl2N4O3 555.506000 |
UDHRMOWCYWTZJA-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143401; PubChem:CID78122085
|
Local ready
Direct docking supported
|
|
E3L006160
BDB006160
|
BDBM143404
Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCN3C(=O)N(C)C)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C30H35Cl2N5O2 568.549000 |
YOXSWOWVTGKRRI-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143404; PubChem:CID78122348
|
Local ready
Direct docking supported
|