| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006161
BDB006161
|
BDBM143405
CC(=O)N1CCCC1Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H32Cl2N4O2 539.507000 |
JZFAHAGJOFEDPR-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143405; PubChem:CID78122349
|
Local ready
Direct docking supported
|
|
E3L006162
BDB006162
|
BDBM143406
Cc1cc(Cl)ccc1C1c2c(nn(Cc3ccccc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C28H24Cl2FN3O 508.424000 |
WPSSCIDRUBTKAN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143406; PubChem:CID71586461
|
Local ready
Direct docking supported
|
|
E3L006163
BDB006163
|
BDBM143407
Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCCC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C28H30Cl2FN3O 514.472000 |
OBXCBYXXTYVDSI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143407; PubChem:CID89601810
|
Local ready
Direct docking supported
|
|
E3L006164
BDB006164
|
BDBM143408
Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C23H22Cl2FN3O2 462.352000 |
HMHZLUVFZNQBTE-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143408; PubChem:CID71586550
|
Local ready
Direct docking supported
|
|
E3L006165
BDB006165
|
BDBM143409
Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C#N)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C28H21Cl2FN4O 519.407000 |
ZNNIQRHOWSRDID-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143409; PubChem:CID71585477
|
Local ready
Direct docking supported
|
|
E3L006166
BDB006166
|
BDBM143410
Cc1cc(Cl)ccc1C1c2c(nn(-c3ccccc3F)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C27H21Cl2F2N3O 512.387000 |
GPSWTWVTPSINSB-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143410; PubChem:CID71586552
|
Local ready
Direct docking supported
|
|
E3L006167
BDB006167
|
BDBM143411
CC(C)c1c2c(nn1CCO)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1Cl
|
C22H19Cl3FN3O2 482.770000 |
WOGRNEPYKNYRAY-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143411; PubChem:CID71586551
|
Local ready
Direct docking supported
|
|
E3L006168
BDB006168
|
BDBM143412
CNS(=O)(=O)Cc1ccc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cccc(Cl)c2F)C3=O)cc1
|
C29H27Cl2FN4O3S 601.531000 |
LHKYSLQAJSHGLY-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143412; PubChem:CID89601521
|
Local ready
Direct docking supported
|
|
E3L006169
BDB006169
|
BDBM143413
Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C)CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C27H29Cl2FN4O 515.460000 |
BIIFEKIGTUMZNZ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143413; PubChem:CID89601341
|
Local ready
Direct docking supported
|
|
E3L006170
BDB006170
|
BDBM143414
Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(Cl)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C27H21Cl3FN3O 528.842000 |
UVNYTNSLCVSVTL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143414; PubChem:CID71586553
|
Local ready
Direct docking supported
|
|
E3L006171
BDB006171
|
BDBM143415
Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C(N)=O)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C28H23Cl2FN4O2 537.422000 |
PHONKNJXSTWJFY-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143415; PubChem:CID71586554
|
Local ready
Direct docking supported
|
|
E3L006172
BDB006172
|
BDBM143416
CC(C)c1c2c(nn1CCO)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)c(F)c1
|
C22H19Cl2F2N3O2 466.315000 |
PKTREAKCQJCNCB-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143416; PubChem:CID71586651
|
Local ready
Direct docking supported
|
|
E3L006173
BDB006173
|
BDBM143417
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(F)cc1)N(c1cccc(Cl)c1F)C2=O
|
C27H22ClF2N3O2 493.941000 |
NTMPRZKGDGPMFD-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143417; PubChem:CID89601180
|
Local ready
Direct docking supported
|
|
E3L006174
BDB006174
|
BDBM143418
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(F)c(F)c1)N(c1cccc(Cl)c1F)C2=O
|
C27H21ClF3N3O2 511.931000 |
FOESSPNKSMUVQU-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143418; PubChem:CID71586654
|
Local ready
Direct docking supported
|
|
E3L006175
BDB006175
|
BDBM143419
CC(C)c1c2c(nn1-c1ccncc1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
|
C25H19Cl2FN4O 481.358000 |
UTRRDMMZSZZPIB-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143419; PubChem:CID71586653
|
Local ready
Direct docking supported
|
|
E3L006176
BDB006176
|
BDBM143420
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(C)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H25ClFN3O2 489.978000 |
YPXWYQIOSVQHBK-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143420; PubChem:CID71586655
|
Local ready
Direct docking supported
|
|
E3L006177
BDB006177
|
BDBM143421
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C27H22Cl2FN3O2 510.396000 |
FXCJXJZTTZWVDL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143421; PubChem:CID71585175
|
Local ready
Direct docking supported
|
|
E3L006178
BDB006178
|
BDBM143422
Cc1cc(Cl)ccc1C1c2c(nn(-c3cc(=O)n(C)c(=O)n3C)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C28H27Cl2N5O3 552.462000 |
HAOXNUGBZDFVPB-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143422; PubChem:CID71585176
|
Local ready
Direct docking supported
|
|
E3L006179
BDB006179
|
BDBM143423
Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C)CC3)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C28H32Cl2N4O 511.497000 |
GNUPSFNBJBWYRB-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143423; PubChem:CID89601136
|
Local ready
Direct docking supported
|
|
E3L006180
BDB006180
|
BDBM143424
Cc1cc(Cl)ccc1C1c2c(nn(C3CCOCC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C26H26Cl2FN3O2 502.417000 |
NOXKBKWUFKOLHB-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143424; PubChem:CID71585177
|
Local ready
Direct docking supported
|