| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006181
BDB006181
|
BDBM143425
COc1ccccc1-n1nc2c(c1C(C)C)C(CC(=O)N1CCOCC1)(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C33H31Cl2FN4O4 637.539000 |
HDAJQNMJDOETDO-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143425; PubChem:CID89601523
|
Local ready
Direct docking supported
|
|
E3L006182
BDB006182
|
BDBM143426
Cc1cc(Cl)ccc1C1c2c(nn(-c3ccccc3Cl)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C27H21Cl3FN3O 528.842000 |
LHXUGFRDBNVUIT-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143426; PubChem:CID89611292
|
Local ready
Direct docking supported
|
|
E3L006183
BDB006183
|
BDBM143427
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
|
C28H24Cl2FN3O2 524.423000 |
UPUQTACBEBMRIU-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143427; PubChem:CID89601440
|
Local ready
Direct docking supported
|
|
E3L006184
BDB006184
|
BDBM143428
Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(F)cc3F)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C27H20Cl2F3N3O 530.377000 |
JFYYWZGFLOOIDT-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143428; PubChem:CID89601671
|
Local ready
Direct docking supported
|
|
E3L006185
BDB006185
|
BDBM143429
Cc1cc(Cl)ccc1C1c2c(nn(CCC#N)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C24H21Cl2FN4O 471.363000 |
LFWZYTLMZYUEFQ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143429; PubChem:CID89601369
|
Local ready
Direct docking supported
|
|
E3L006186
BDB006186
|
BDBM143430
Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C(C)C)C(=O)N1c1ccc(F)c(Cl)c1
|
C23H22Cl2FN3O2 462.352000 |
KVHUHKCJHOHTMI-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143430; PubChem:CID89601518
|
Local ready
Direct docking supported
|
|
E3L006187
BDB006187
|
BDBM143431
Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C#N)cc3C)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C29H23Cl2FN4O 533.434000 |
VCGVUTSFODIAFH-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143431; PubChem:CID89601188
|
Local ready
Direct docking supported
|
|
E3L006188
BDB006188
|
BDBM143433
Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C2CCC2)C(=O)N1c1cccc(Cl)c1F
|
C24H22Cl2FN3O2 474.363000 |
KVQBAECCFMFALF-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143433; PubChem:CID89601455
|
Local ready
Direct docking supported
|
|
E3L006189
BDB006189
|
BDBM143434
Cc1cc(Cl)ccc1C1c2c(nn(-c3cccc(C#N)c3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C28H21Cl2FN4O 519.407000 |
RUFLPMXZYPSUOV-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143434; PubChem:CID89601202
|
Local ready
Direct docking supported
|
|
E3L006190
BDB006190
|
BDBM143435
Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C24H25Cl2N3O2 458.389000 |
GLJMWFSFNGOCDG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143435; PubChem:CID89601377
|
Local ready
Direct docking supported
|
|
E3L006191
BDB006191
|
BDBM143436
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H27Cl2N3O2 520.460000 |
ZPZFPPPXKLFRBC-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143436; PubChem:CID89601405
|
Local ready
Direct docking supported
|
|
E3L006192
BDB006192
|
BDBM143437
Cc1cc(Cl)ccc1C1c2c(nn(CCO)c2C2CC2)C(=O)N1c1cccc(Cl)c1F
|
C23H20Cl2FN3O2 460.336000 |
QRUJCXIVKXOPIJ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143437; PubChem:CID89601371
|
Local ready
Direct docking supported
|
|
E3L006193
BDB006193
|
BDBM143438
COc1ccccc1-n1nc2c(c1C1CC1)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
|
C28H22Cl2FN3O2 522.407000 |
RSKWVWWNOULHKJ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143438; PubChem:CID89601892
|
Local ready
Direct docking supported
|
|
E3L006194
BDB006194
|
BDBM143439
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(F)cc1F)C2=O
|
C28H23Cl2F2N3O2 542.413000 |
VJIXYTFQQQTOIG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143439; PubChem:CID89601973
|
Local ready
Direct docking supported
|
|
E3L006195
BDB006195
|
BDBM143440
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C27H22Cl2FN3O2 510.396000 |
DUNHLTCPPXISMB-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143440; PubChem:CID89601326
|
Local ready
Direct docking supported
|
|
E3L006196
BDB006196
|
BDBM143441
COC(=O)CCC1(c2ccc(Cl)cc2)c2c(nn(-c3ccccc3OC)c2C(C)C)C(=O)N1c1ccc(F)c(Cl)c1
|
C31H28Cl2FN3O4 596.486000 |
OATMHJTYDZFHJL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM143441
|
Local ready
Direct docking supported
|
|
E3L006197
BDB006197
|
BDBM143442
CCOC(=O)C1(c2ccc(Cl)cc2)c2c(nn(-c3ccccc3OC)c2C(C)C)C(=O)N1c1ccc(F)c(Cl)c1
|
C30H26Cl2FN3O4 582.459000 |
WYNJGGKMGSZIJC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143442; PubChem:CID89601811
|
Local ready
Direct docking supported
|
|
E3L006198
BDB006198
|
BDBM143443
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cncc(Cl)c1)C2=O
|
C27H24Cl2N4O2 507.421000 |
DQKSQGUSULGQMU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143443; PubChem:CID89601467
|
Local ready
Direct docking supported
|
|
E3L006199
BDB006199
|
BDBM143444
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
|
C32H34Cl2N4O3 593.555000 |
YBMQYNARIZUNIO-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143444; PubChem:CID78113953
|
Local ready
Direct docking supported
|
|
E3L006200
BDB006200
|
BDBM143445
COc1ccccc1-n1nc2c(c1C(C)C)C(C)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C28H24Cl2FN3O2 524.423000 |
QWSVSMXQIURNKZ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143445; PubChem:CID89601551
|
Local ready
Direct docking supported
|