| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006281
BDB006281
|
BDBM143661
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C27H25ClN8O3 545.003000 |
LWGPOQSLGYFKSK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143661; PubChem:CID89601506
|
Local ready
Direct docking supported
|
|
E3L006282
BDB006282
|
BDBM143665
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
|
C26H23ClN8O3 530.976000 |
ATMKSZMRLDHODZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143665; PubChem:CID89601175
|
Local ready
Direct docking supported
|
|
E3L006283
BDB006283
|
BDBM143669
COc1ncc(-n2nc3c(c2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
LIFXZKFYYIPQBT-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM143669
|
Local ready
Direct docking supported
|
|
E3L006284
BDB006284
|
BDBM143670
COc1ncc(-n2nc3c(c2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
LIFXZKFYYIPQBT-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM143670
|
Local ready
Direct docking supported
|
|
E3L006285
BDB006285
|
BDBM143671
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H27ClN8O3 559.030000 |
RQRGUXOSYRMAOC-DEOSSOPVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143671; PubChem:CID89602031
|
Local ready
Direct docking supported
|
|
E3L006286
BDB006286
|
BDBM143672
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H27ClN8O3 559.030000 |
RQRGUXOSYRMAOC-XMMPIXPASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143672; PubChem:CID89602019
|
Local ready
Direct docking supported
|
|
E3L006287
BDB006287
|
BDBM143673
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
|
C26H25Cl2N7O3 554.438000 |
SJSSRJQZFGJFOX-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143673; PubChem:CID89601442
|
Local ready
Direct docking supported
|
|
E3L006288
BDB006288
|
BDBM143674
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
|
C26H25Cl2N7O3 554.438000 |
SJSSRJQZFGJFOX-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143674; PubChem:CID117702157
|
Local ready
Direct docking supported
|
|
E3L006289
BDB006289
|
BDBM143675
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
|
C27H25ClN8O3 545.003000 |
VFMRTUQQYDQOGC-HSZRJFAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143675; PubChem:CID89601608
|
Local ready
Direct docking supported
|
|
E3L006290
BDB006290
|
BDBM143676
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
|
C27H25ClN8O3 545.003000 |
VFMRTUQQYDQOGC-QHCPKHFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM143676
|
Local ready
Direct docking supported
|
|
E3L006291
BDB006291
|
BDBM143677
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2F)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H23Cl2FN6O4 573.412000 |
RIGFJBPAOUYYDK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143677; PubChem:CID89611252
|
Local ready
Direct docking supported
|
|
E3L006292
BDB006292
|
BDBM143682
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2F)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C26H23Cl2FN6O4 573.412000 |
KRKJHAZDWLVODZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143682; PubChem:CID89611104
|
Local ready
Direct docking supported
|
|
E3L006293
BDB006293
|
BDBM143685
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H23Cl2FN6O4 573.412000 |
YDAUQLMQAVQZLU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM143685
|
Local ready
Direct docking supported
|
|
E3L006294
BDB006294
|
BDBM143689
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)c(F)c2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C26H23Cl2FN6O4 573.412000 |
FQEUKQUHLSJANT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143689; PubChem:CID89611240
|
Local ready
Direct docking supported
|
|
E3L006295
BDB006295
|
BDBM143692
[C-]#[N+]c1ccc(C2c3c(nn(-c4cnc(OC)nc4OC)c3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)c(F)c1
|
C27H23ClFN7O4 563.977000 |
SBTIBAXZWFMNEF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143692; PubChem:CID91801083
|
Local ready
Direct docking supported
|
|
E3L006296
BDB006296
|
BDBM143696
[C-]#[N+]c1ccc(C2c3c(nn(-c4cnc(OC)nc4OC)c3C(C)C)C(=O)N2c2cc(Cl)cn(C)c2=O)cc1F
|
C27H23ClFN7O4 563.977000 |
LQQCZFNYHWBMBO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143696; PubChem:CID91801084
|
Local ready
Direct docking supported
|
|
E3L006297
BDB006297
|
BDBM143700
[C-]#[N+]c1ccc(C2c3c(nn(-c4cnc(OC)nc4OC)c3C(C)C)C(=O)N2c2cc(Cl)cn(C)c2=O)c(F)c1
|
C27H23ClFN7O4 563.977000 |
XQWVYYDDSOFRPG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143700; PubChem:CID91801085
|
Local ready
Direct docking supported
|
|
E3L006298
BDB006298
|
BDBM143703
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H26ClFN8O3 577.020000 |
QCBBDTOZLNYFGQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143703; PubChem:CID89601953
|
Local ready
Direct docking supported
|
|
E3L006299
BDB006299
|
BDBM143708
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H26ClFN8O3 577.020000 |
OPHHVKUMEIMJFY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143708; PubChem:CID89601557
|
Local ready
Direct docking supported
|
|
E3L006300
BDB006300
|
BDBM143711
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cc(Cl)c[nH]c1=O)C2=O
|
C27H24ClFN8O3 562.993000 |
UBDXCWOLGCQOJC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM143711
|
Local ready
Direct docking supported
|