| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006241
BDB006241
|
BDBM143526
COc1cnc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H25Cl2N5O2 546.458000 |
LXJBEGXWXSMNHG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143526; PubChem:CID89601240
|
Local ready
Direct docking supported
|
|
E3L006242
BDB006242
|
BDBM143530
COc1cnc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H24Cl2N6O3 563.445000 |
HVRFIYKARUWFKC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143530; PubChem:CID89601182
|
Local ready
Direct docking supported
|
|
E3L006243
BDB006243
|
BDBM143533
[C-]#[N+]c1ccc(C2c3c(nn(-c4cc(C#N)ccc4OC)c3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
|
C30H24ClN5O2 522.008000 |
KEUYAOJPQJIQBZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143533; PubChem:CID91801045
|
Local ready
Direct docking supported
|
|
E3L006244
BDB006244
|
BDBM143537
[C-]#[N+]c1ccc(C2c3c(nn(-c4cc(C#N)ccc4OC)c3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)c(C)c1
|
C30H25ClN6O3 553.022000 |
ZGKZODONZOIGSW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143537; PubChem:CID91801049
|
Local ready
Direct docking supported
|
|
E3L006245
BDB006245
|
BDBM143541
[C-]#[N+]c1ccc(C2c3c(nn(-c4cc(C#N)ccc4OC)c3C(C)C)C(=O)N2c2cc(Cl)ccc2C)c(C)c1
|
C31H26ClN5O2 536.035000 |
XZSCIWBDQSNTCS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143541; PubChem:CID91801053
|
Local ready
Direct docking supported
|
|
E3L006246
BDB006246
|
BDBM143544
Cc1cc(Cl)ccc1[C@H]1c2c(nn(CCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C23H22Cl2FN3O2 462.352000 |
HMHZLUVFZNQBTE-QFIPXVFZSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143544; PubChem:CID89601620
|
Local ready
Direct docking supported
|
|
E3L006247
BDB006247
|
BDBM143545
Cc1cc(Cl)ccc1[C@@H]1c2c(nn(CCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C23H22Cl2FN3O2 462.352000 |
HMHZLUVFZNQBTE-JOCHJYFZSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143545; PubChem:CID89601994
|
Local ready
Direct docking supported
|
|
E3L006248
BDB006248
|
BDBM143546
COc1ccccc1-n1nc2c(c1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H27Cl2N3O2 520.460000 |
ZPZFPPPXKLFRBC-NDEPHWFRSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143546; PubChem:CID89601404
|
Local ready
Direct docking supported
|
|
E3L006249
BDB006249
|
BDBM143547
COc1ccccc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H27Cl2N3O2 520.460000 |
ZPZFPPPXKLFRBC-MUUNZHRXSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143547; PubChem:CID89611185
|
Local ready
Direct docking supported
|
|
E3L006250
BDB006250
|
BDBM143548
COc1ccccc1-n1nc2c(c1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
|
C32H34Cl2N4O3 593.555000 |
YBMQYNARIZUNIO-HKBQPEDESA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143548; PubChem:CID71565460
|
Local ready
Direct docking supported
|
|
E3L006251
BDB006251
|
BDBM143549
COc1ccccc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O
|
C32H34Cl2N4O3 593.555000 |
YBMQYNARIZUNIO-WJOKGBTCSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143549; PubChem:CID89602035
|
Local ready
Direct docking supported
|
|
E3L006252
BDB006252
|
BDBM143550
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
PANLTUPSUITZKH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143550; PubChem:CID89611183
|
Local ready
Direct docking supported
|
|
E3L006253
BDB006253
|
BDBM143554
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C27H26Cl2N6O4 569.449000 |
ZUSGXOJEHMHMML-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143554; PubChem:CID89601307
|
Local ready
Direct docking supported
|
|
E3L006254
BDB006254
|
BDBM143558
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
|
C26H25Cl2N7O3 554.438000 |
SJSSRJQZFGJFOX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143558; PubChem:CID89601420
|
Local ready
Direct docking supported
|
|
E3L006255
BDB006255
|
BDBM143571
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C27H27Cl2N7O3 568.465000 |
OWFJNPMLQSQXJK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143571; PubChem:CID89601503
|
Local ready
Direct docking supported
|
|
E3L006256
BDB006256
|
BDBM143574
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C27H27Cl2N7O3 568.465000 |
UZHVOERTZALWJN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143574; PubChem:CID89601606
|
Local ready
Direct docking supported
|
|
E3L006257
BDB006257
|
BDBM143577
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H27ClN8O3 559.030000 |
RQRGUXOSYRMAOC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143577; PubChem:CID89601659
|
Local ready
Direct docking supported
|
|
E3L006258
BDB006258
|
BDBM143581
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H27ClN8O3 559.030000 |
QFACTYPVKZDPLP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143581; PubChem:CID89601251
|
Local ready
Direct docking supported
|
|
E3L006259
BDB006259
|
BDBM143584
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
OIFYSZRTTNMVQD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143584; PubChem:CID89601291
|
Local ready
Direct docking supported
|
|
E3L006260
BDB006260
|
BDBM143590
COc1ncc(-n2nc3c(c2C(C)C)[C@H](c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C27H26Cl2N6O4 569.449000 |
AYJVXDFOPGRLNI-QHCPKHFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143590; PubChem:CID89602053
|
Local ready
Direct docking supported
|