| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006261
BDB006261
|
BDBM143591
COc1ncc(-n2nc3c(c2C(C)C)[C@@H](c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C27H26Cl2N6O4 569.449000 |
AYJVXDFOPGRLNI-HSZRJFAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143591; PubChem:CID89601316
|
Local ready
Direct docking supported
|
|
E3L006262
BDB006262
|
BDBM143592
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
LKJGYPXCEQDHSF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143592; PubChem:CID89601432
|
Local ready
Direct docking supported
|
|
E3L006263
BDB006263
|
BDBM143598
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
|
C26H25Cl2N7O3 554.438000 |
IERFWHRPSNQCKG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143598; PubChem:CID89601618
|
Local ready
Direct docking supported
|
|
E3L006264
BDB006264
|
BDBM143602
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O
|
C27H25ClN8O3 545.003000 |
VFMRTUQQYDQOGC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143602; PubChem:CID71585378
|
Local ready
Direct docking supported
|
|
E3L006265
BDB006265
|
BDBM143606
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(C#N)cc1)N(c1c[nH]c(=O)c(Cl)c1)C2=O
|
C27H25ClN8O3 545.003000 |
HZMWETDTDRJJRB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143606; PubChem:CID71585379
|
Local ready
Direct docking supported
|
|
E3L006266
BDB006266
|
BDBM143610
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
|
C26H22ClN7O4 531.960000 |
SAENTOWOUZIBGI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143610; PubChem:CID71585380
|
Local ready
Direct docking supported
|
|
E3L006267
BDB006267
|
BDBM143615
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C26H22ClN7O4 531.960000 |
BBYSZUMVPYJQOO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143615; PubChem:CID89602059
|
Local ready
Direct docking supported
|
|
E3L006268
BDB006268
|
BDBM143619
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C27H24ClN7O4 545.987000 |
IOZOLCKZPLYLKQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143619; PubChem:CID89601500
|
Local ready
Direct docking supported
|
|
E3L006269
BDB006269
|
BDBM143622
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C27H24ClN7O4 545.987000 |
FFDKGWMMRQCCRD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143622; PubChem:CID89601284
|
Local ready
Direct docking supported
|
|
E3L006270
BDB006270
|
BDBM143625
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C26H25Cl2N7O3 554.438000 |
FWEMNIDYMWXHEJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143625; PubChem:CID89601765
|
Local ready
Direct docking supported
|
|
E3L006271
BDB006271
|
BDBM143635
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
LIFXZKFYYIPQBT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143635; PubChem:CID89601520
|
Local ready
Direct docking supported
|
|
E3L006272
BDB006272
|
BDBM143636
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C25H23Cl2N7O3 540.411000 |
FVWMRADKCANHAA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143636; PubChem:CID89602029
|
Local ready
Direct docking supported
|
|
E3L006273
BDB006273
|
BDBM143640
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1
|
C25H23Cl2N7O3 540.411000 |
AYHKSUDVKVQKRY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143640; PubChem:CID89601514
|
Local ready
Direct docking supported
|
|
E3L006274
BDB006274
|
BDBM143644
COc1ncc(-n2nc3c(c2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
OIFYSZRTTNMVQD-OAQYLSRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143644; PubChem:CID89601948
|
Local ready
Direct docking supported
|
|
E3L006275
BDB006275
|
BDBM143645
COc1ncc(-n2nc3c(c2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
OIFYSZRTTNMVQD-NRFANRHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143645; PubChem:CID89601305
|
Local ready
Direct docking supported
|
|
E3L006276
BDB006276
|
BDBM143646
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C27H25ClN8O3 545.003000 |
RWNQWEFSMWIPTO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143646; PubChem:CID89601962
|
Local ready
Direct docking supported
|
|
E3L006277
BDB006277
|
BDBM143651
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H27ClN8O3 559.030000 |
QFACTYPVKZDPLP-XMMPIXPASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143651; PubChem:CID89601250
|
Local ready
Direct docking supported
|
|
E3L006278
BDB006278
|
BDBM143652
COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H27ClN8O3 559.030000 |
QFACTYPVKZDPLP-DEOSSOPVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143652; PubChem:CID89601380
|
Local ready
Direct docking supported
|
|
E3L006279
BDB006279
|
BDBM143653
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H25Cl2N7O3 554.438000 |
JFMPRDLNBMLXEF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143653; PubChem:CID89611236
|
Local ready
Direct docking supported
|
|
E3L006280
BDB006280
|
BDBM143657
CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C26H23ClN8O3 530.976000 |
FYNWTBPRYFLVCU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143657; PubChem:CID89601418
|
Local ready
Direct docking supported
|