| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006221
BDB006221
|
BDBM143474
CNC(=O)c1ccc(OC)c(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c1
|
C30H29Cl2N5O4 594.499000 |
JGDWYYYDKDRIQZ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143474; PubChem:CID71585277
|
Local ready
Direct docking supported
|
|
E3L006222
BDB006222
|
BDBM143477
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(CCN(C)C)c1)C2=O
|
C30H31Cl2N5O3 580.516000 |
IFRLFSYFJZFISV-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143477; PubChem:CID89601599
|
Local ready
Direct docking supported
|
|
E3L006223
BDB006223
|
BDBM143478
Cc1cc(Cl)ccc1C1c2c(nn(C3CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C24H22Cl2FN3O 458.364000 |
QCXFDHNMOCWGOO-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143478; PubChem:CID89601419
|
Local ready
Direct docking supported
|
|
E3L006224
BDB006224
|
BDBM143479
Cc1cc(Cl)ccc1C1c2c(nn(C3CCC(O)CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C27H28Cl2FN3O2 516.444000 |
JBEQAJPKJMSHFR-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143479; PubChem:CID89601410
|
Local ready
Direct docking supported
|
|
E3L006225
BDB006225
|
BDBM143480
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1ccnc(Cl)c1)C2=O
|
C27H24Cl2N4O2 507.421000 |
LQFQEWGXGDBOGP-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143480; PubChem:CID89601791
|
Local ready
Direct docking supported
|
|
E3L006226
BDB006226
|
BDBM143483
COc1cnc(Cl)cc1N1C(=O)c2nn(-c3ccccc3OC)c(C(C)C)c2C1c1ccc(Cl)cc1C
|
C28H26Cl2N4O3 537.447000 |
DDNUWIGTTWWNTD-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143483; PubChem:CID89601657
|
Local ready
Direct docking supported
|
|
E3L006227
BDB006227
|
BDBM143488
CC(C)c1c2c(nn1-c1cn[nH]c1)C(=O)N(c1cccc(Cl)c1F)C2c1ccc(Cl)cc1
|
C23H18Cl2FN5O 470.335000 |
BBYYJQOKOHLPCF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143488; PubChem:CID89601976
|
Local ready
Direct docking supported
|
|
E3L006228
BDB006228
|
BDBM143493
COc1ccncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C26H21Cl2FN4O2 511.384000 |
URYVVMMWEFMDLZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143493; PubChem:CID89601239
|
Local ready
Direct docking supported
|
|
E3L006229
BDB006229
|
BDBM143496
COc1ccncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C28H26Cl2N4O2 521.448000 |
MIGFPEUHNSPEGD-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143496; PubChem:CID89601469
|
Local ready
Direct docking supported
|
|
E3L006230
BDB006230
|
BDBM143497
CC(C)(C)c1[nH]nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C21H18Cl2FN3O 418.299000 |
NFPQHOKNWHJKMC-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143497; PubChem:CID89601617
|
Local ready
Direct docking supported
|
|
E3L006231
BDB006231
|
BDBM143499
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1OCc1nn[nH]n1)C2=O
|
C29H25Cl2N7O3 590.471000 |
LXVKCNFEVHJFNO-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143499; PubChem:CID89601372
|
Local ready
Direct docking supported
|
|
E3L006232
BDB006232
|
BDBM143507
COc1ccc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H26Cl2N4O2 545.470000 |
XDCIHZNPQQRJAT-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143507; PubChem:CID89601858
|
Local ready
Direct docking supported
|
|
E3L006233
BDB006233
|
BDBM143511
COc1ccc(CN)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H30Cl2N4O2 549.502000 |
ZJWOFSLLBIUKPW-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143511; PubChem:CID89601203
|
Local ready
Direct docking supported
|
|
E3L006234
BDB006234
|
BDBM143512
COc1ccc(CNC(C)=O)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O3 591.539000 |
WHEWAAXRLULZDS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143512; PubChem:CID89611085
|
Local ready
Direct docking supported
|
|
E3L006235
BDB006235
|
BDBM143513
COc1ccc(CNC=O)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C31H30Cl2N4O3 577.512000 |
POEYXKUAFFVQOZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143513; PubChem:CID89611086
|
Local ready
Direct docking supported
|
|
E3L006236
BDB006236
|
BDBM143514
COc1ccc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C29H25Cl2N5O3 562.457000 |
PMPUDZCQKFOGSX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143514; PubChem:CID89601214
|
Local ready
Direct docking supported
|
|
E3L006237
BDB006237
|
BDBM143517
COc1ccc(CN)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C29H29Cl2N5O3 566.489000 |
DLKYKILDEXFUBY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143517; PubChem:CID71585278
|
Local ready
Direct docking supported
|
|
E3L006238
BDB006238
|
BDBM143518
COc1ccc(CNC(C)=O)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C31H31Cl2N5O4 608.526000 |
XEXIOQWTQYGVGN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143518; PubChem:CID71585279
|
Local ready
Direct docking supported
|
|
E3L006239
BDB006239
|
BDBM143519
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C27H26Cl2N6O4 569.449000 |
AYJVXDFOPGRLNI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143519; PubChem:CID71585377
|
Local ready
Direct docking supported
|
|
E3L006240
BDB006240
|
BDBM143523
COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C28H27Cl2N5O3 552.462000 |
FMTUQXWHYUZQKX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143523; PubChem:CID89601444
|
Local ready
Direct docking supported
|