| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L064301
BDB064301
|
BDBM50631431
COC[C@@H](CC(C)C)NC1=N/C(=C\c2ccc3ncsc3n2)C(=O)N1
|
C17H21N5O2S 359.455000 |
PPZINUUIYSVIGC-AISSWFOISA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM50631431; PubChem:CID172465022
|
Local ready
Direct docking supported
|
|
E3L064302
BDB064302
|
BDBM50631443
CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](N)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1
|
C37H47Cl2N5O4S 728.787000 |
WZJUTDURUQJHRV-PQQNNWGCSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631443; PubChem:CID172465996
|
Local ready
Direct docking supported
|
|
E3L064303
BDB064303
|
BDBM50631444
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1ccccc1Cl
|
C31H34Cl2FN3O4 602.534000 |
KJKPPWDQIYGDKU-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631444; PubChem:CID172445883
|
Local ready
Direct docking supported
|
|
E3L064304
BDB064304
|
BDBM50631445
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1
|
C31H34Cl2FN3O4 602.534000 |
KQHNSALOIYLNQI-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631445; PubChem:CID172444227
|
Local ready
Direct docking supported
|
|
E3L064305
BDB064305
|
BDBM50631446
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1ccc(Cl)cc1
|
C31H34Cl2FN3O4 602.534000 |
JAUCTTOPFSFTQT-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631446; PubChem:CID172444499
|
Local ready
Direct docking supported
|
|
E3L064306
BDB064306
|
BDBM50631447
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1Cl
|
C31H33Cl3FN3O4 636.979000 |
VLWYISNAQGGZPS-LJQIRTBHSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631447; PubChem:CID172451300
|
Local ready
Direct docking supported
|
|
E3L064307
BDB064307
|
BDBM50631448
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1cccc(C)c1
|
C32H37ClFN3O4 582.116000 |
IGTGOKWCKVJTMF-PJGOFDOSSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631448; PubChem:CID172442818
|
Local ready
Direct docking supported
|
|
E3L064308
BDB064308
|
BDBM50631449
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1cccc(C(F)(F)F)c1
|
C32H34ClF4N3O4 636.086000 |
QPQCSMOYZYMLEP-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631449
|
Local ready
Direct docking supported
|
|
E3L064309
BDB064309
|
BDBM50631450
COc1cccc([C@H]2[C@H](C(=O)Nc3ccc(C(=O)O)cc3OC)N[C@@H](CC(C)(C)C)[C@]2(CN)c2ccc(Cl)cc2F)c1
|
C32H37ClFN3O5 598.115000 |
NBYBNLXKIUYRBI-PJGOFDOSSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631450; PubChem:CID172459682
|
Local ready
Direct docking supported
|
|
E3L064310
BDB064310
|
BDBM50631451
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1ccccc1F
|
C31H34ClF2N3O4 586.079000 |
JWOPLFZFIUDEON-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631451; PubChem:CID172440918
|
Local ready
Direct docking supported
|
|
E3L064311
BDB064311
|
BDBM50631452
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1cccc(F)c1
|
C31H34ClF2N3O4 586.079000 |
QYBTYRKQNXDCKQ-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631452; PubChem:CID172453231
|
Local ready
Direct docking supported
|
|
E3L064312
BDB064312
|
BDBM50631453
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1ccc(F)cc1
|
C31H34ClF2N3O4 586.079000 |
LXCKHDAPYQUUAL-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631453; PubChem:CID172465083
|
Local ready
Direct docking supported
|
|
E3L064313
BDB064313
|
BDBM50631454
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2ccc(Cl)cc2F)[C@H]1c1cccc(F)c1F
|
C31H33ClF3N3O4 604.069000 |
CWBBWGAANNANLJ-LJQIRTBHSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631454; PubChem:CID172449002
|
Local ready
Direct docking supported
|
|
E3L064314
BDB064314
|
BDBM50631455
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2cc(Cl)ccc2F)[C@H]1c1ccccc1Cl
|
C31H34Cl2FN3O4 602.534000 |
AAGXKXMEGGPOIV-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631455; PubChem:CID172470556
|
Local ready
Direct docking supported
|
|
E3L064315
BDB064315
|
BDBM50631456
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2cc(Cl)ccc2F)[C@H]1c1cccc(Cl)c1
|
C31H34Cl2FN3O4 602.534000 |
GDEDLUGXYVYGGS-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631456; PubChem:CID172460601
|
Local ready
Direct docking supported
|
|
E3L064316
BDB064316
|
BDBM50631457
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2cc(Cl)ccc2F)[C@H]1c1ccc(Cl)cc1
|
C31H34Cl2FN3O4 602.534000 |
RNJLHNATDYXUDR-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631457; PubChem:CID172452169
|
Local ready
Direct docking supported
|
|
E3L064317
BDB064317
|
BDBM50631458
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CN)(c2cc(Cl)ccc2F)[C@H]1c1cccc(Cl)c1Cl
|
C31H33Cl3FN3O4 636.979000 |
GVPGYQYFZIEHJU-LJQIRTBHSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631458; PubChem:CID172445132
|
Local ready
Direct docking supported
|
|
E3L064318
BDB064318
|
BDBM50631459
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H32Cl2FN3O4 600.518000 |
VKSSIXZETBBSJT-LJQIRTBHSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631459
|
Local ready
Direct docking supported
|
|
E3L064319
BDB064319
|
BDBM50631460
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1ccccc1Cl
|
C31H33Cl2N3O4 582.528000 |
YYFDXNFZFADDJN-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631460; PubChem:CID167188239
|
Local ready
Direct docking supported
|
|
E3L064320
BDB064320
|
BDBM50631461
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1
|
C31H33Cl2N3O4 582.528000 |
ZCJJLRSSRNBJIA-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631461; PubChem:CID167188236
|
Local ready
Direct docking supported
|