| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L064321
BDB064321
|
BDBM50631462
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1ccc(Cl)cc1
|
C31H33Cl2N3O4 582.528000 |
FBVPKAXPXAGDGZ-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631462; PubChem:CID167188915
|
Local ready
Direct docking supported
|
|
E3L064322
BDB064322
|
BDBM50631463
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1Cl
|
C31H32Cl3N3O4 616.973000 |
IFWDFAOQSYOSFH-LJQIRTBHSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631463; PubChem:CID172449853
|
Local ready
Direct docking supported
|
|
E3L064323
BDB064323
|
BDBM50631464
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(C)c1
|
C32H36ClN3O4 562.110000 |
JNQWGJBQEUVYPV-PJGOFDOSSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631464; PubChem:CID172462007
|
Local ready
Direct docking supported
|
|
E3L064324
BDB064324
|
BDBM50631465
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(C(F)(F)F)c1
|
C32H33ClF3N3O4 616.080000 |
RTFYBTTUWIIJAS-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631465
|
Local ready
Direct docking supported
|
|
E3L064325
BDB064325
|
BDBM50631466
COc1cccc([C@H]2[C@H](C(=O)Nc3ccc(C(=O)O)cc3OC)N[C@@H](CC(C)(C)C)[C@@]23CNc2cc(Cl)ccc23)c1
|
C32H36ClN3O5 578.109000 |
HXVNIXFBVHOTNH-PJGOFDOSSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631466; PubChem:CID172470918
|
Local ready
Direct docking supported
|
|
E3L064326
BDB064326
|
BDBM50631467
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1ccccc1F
|
C31H33ClFN3O4 566.073000 |
JIAPTPKAIWJVDT-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631467; PubChem:CID167188248
|
Local ready
Direct docking supported
|
|
E3L064327
BDB064327
|
BDBM50631468
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(F)c1
|
C31H33ClFN3O4 566.073000 |
CTRJCMDYSUHZCI-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631468; PubChem:CID172444124
|
Local ready
Direct docking supported
|
|
E3L064328
BDB064328
|
BDBM50631469
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1ccc(F)cc1
|
C31H33ClFN3O4 566.073000 |
FAIRLZFXBHHFDY-QZIGDIDDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50631469; PubChem:CID172444593
|
Local ready
Direct docking supported
|
|
E3L064329
BDB064329
|
BDBM50631470
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(F)c1F
|
C31H32ClF2N3O4 584.063000 |
LVUBVNZTMIPTKB-LJQIRTBHSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631470; PubChem:CID172456492
|
Local ready
Direct docking supported
|
|
E3L064330
BDB064330
|
BDBM50631471
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3ccc(Cl)cc32)[C@H]1c1ccccc1Cl
|
C31H33Cl2N3O4 582.528000 |
FIFDRKQUUFSAMQ-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631471; PubChem:CID167188754
|
Local ready
Direct docking supported
|
|
E3L064331
BDB064331
|
BDBM50631472
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3ccc(Cl)cc32)[C@H]1c1cccc(Cl)c1
|
C31H33Cl2N3O4 582.528000 |
MATKGZSLMVEINL-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631472; PubChem:CID167188914
|
Local ready
Direct docking supported
|
|
E3L064332
BDB064332
|
BDBM50631473
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3ccc(Cl)cc32)[C@H]1c1ccc(Cl)cc1
|
C31H33Cl2N3O4 582.528000 |
QFJZCGUFJQNVTK-QZIGDIDDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631473; PubChem:CID172440749
|
Local ready
Direct docking supported
|
|
E3L064333
BDB064333
|
BDBM50631474
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3ccc(Cl)cc32)[C@H]1c1cccc(Cl)c1Cl
|
C31H32Cl3N3O4 616.973000 |
JFQUVXMAMAXJRE-LJQIRTBHSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50631474; PubChem:CID167189074
|
Local ready
Direct docking supported
|
|
E3L064334
BDB064334
|
BDBM50631475
COc1cc(C(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C31H33Cl2FN4O3 599.534000 |
OEKPQJDPZAKXBX-LJQIRTBHSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631475
|
Local ready
Direct docking supported
|
|
E3L064335
BDB064335
|
BDBM50631476
CNC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(CNc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C32H35Cl2FN4O3 613.561000 |
ZPQMJWAPZQDKRB-ULWUHOHFSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631476
|
Local ready
Direct docking supported
|
|
E3L064336
BDB064336
|
BDBM50631477
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(CN(C)c3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C32H34Cl2FN3O4 614.545000 |
AMSZYZPTYQFKPO-ULWUHOHFSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631477
|
Local ready
Direct docking supported
|
|
E3L064337
BDB064337
|
BDBM50631478
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(Cl)c2F)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H36Cl2FN3O4 628.572000 |
DDFMERDYHWVZDV-HNZCNSHZSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631478
|
Local ready
Direct docking supported
|
|
E3L064338
BDB064338
|
BDBM50631479
COc1cc(C(=O)O)ccc1NC(=O)[C@H]1[C@H](c2cccc(Cl)c2F)[C@]2(CNc3cc(Cl)ccc32)[C@H](CC(C)(C)C)N1C
|
C32H34Cl2FN3O4 614.545000 |
XWQWSVNMTNZUMN-ULWUHOHFSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631479
|
Local ready
Direct docking supported
|
|
E3L064339
BDB064339
|
BDBM50631480
CCCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(Cl)c2F)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C34H38Cl2FN3O4 642.599000 |
ZRDNPEUOPQHDIO-QGHWIGIDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631480
|
Local ready
Direct docking supported
|
|
E3L064340
BDB064340
|
BDBM50631481
CCCCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(Cl)c2F)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C35H40Cl2FN3O4 656.626000 |
IEDYKXIAONMXIM-JNHBBQSGSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631481
|
Local ready
Direct docking supported
|