| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L064341
BDB064341
|
BDBM50631482
COc1cc(C(=O)O)ccc1NC(=O)[C@H]1[C@H](c2cccc(F)c2F)[C@]2(CNc3cc(Cl)ccc32)[C@H](CC(C)(C)C)N1C
|
C32H34ClF2N3O4 598.090000 |
ITYKWNHAABEFLF-ULWUHOHFSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631482
|
Local ready
Direct docking supported
|
|
E3L064342
BDB064342
|
BDBM50631483
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(F)c2F)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H36ClF2N3O4 612.117000 |
CAASPMRVZUIUHV-HNZCNSHZSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631483
|
Local ready
Direct docking supported
|
|
E3L064343
BDB064343
|
BDBM50631484
CCCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(F)c2F)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C34H38ClF2N3O4 626.144000 |
STMWXPZBSNCMIH-QGHWIGIDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631484
|
Local ready
Direct docking supported
|
|
E3L064344
BDB064344
|
BDBM50631485
CCCCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(F)c2F)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C35H40ClF2N3O4 640.171000 |
LPLSXPSLBPAZCA-JNHBBQSGSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631485
|
Local ready
Direct docking supported
|
|
E3L064345
BDB064345
|
BDBM50631486
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2ccccc2Cl)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H37Cl2N3O4 610.582000 |
UYGIJFXVKWOFNK-MKYOLNSUSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631486
|
Local ready
Direct docking supported
|
|
E3L064346
BDB064346
|
BDBM50631487
CCN1[C@H](C(=O)Nc2ccc(C(=O)O)cc2OC)[C@@H](c2cccc(Cl)c2)[C@@]2(CNc3cc(Cl)ccc32)[C@H]1CC(C)(C)C
|
C33H37Cl2N3O4 610.582000 |
AJQDQXYTMUFRRF-NBJHOTSESA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631487
|
Local ready
Direct docking supported
|
|
E3L064347
BDB064347
|
BDBM50631488
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2ccc(Cl)cc2)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H37Cl2N3O4 610.582000 |
HNLQWZJAYNTRCP-MKYOLNSUSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631488
|
Local ready
Direct docking supported
|
|
E3L064348
BDB064348
|
BDBM50631489
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(Cl)c2Cl)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H36Cl3N3O4 645.027000 |
VFWPTBLHVAKSDF-HNZCNSHZSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631489
|
Local ready
Direct docking supported
|
|
E3L064349
BDB064349
|
BDBM50631490
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(C)c2)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C34H40ClN3O4 590.164000 |
YKZLJNUAIUUUBR-IANDGLOUSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631490
|
Local ready
Direct docking supported
|
|
E3L064350
BDB064350
|
BDBM50631491
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(OC)c2)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C34H40ClN3O5 606.163000 |
RHJDRQANIQSVFG-IANDGLOUSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631491
|
Local ready
Direct docking supported
|
|
E3L064351
BDB064351
|
BDBM50631492
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2ccccc2F)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H37ClFN3O4 594.127000 |
ZYPVPNMCWQOTCC-MKYOLNSUSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631492
|
Local ready
Direct docking supported
|
|
E3L064352
BDB064352
|
BDBM50631493
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(F)c2)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H37ClFN3O4 594.127000 |
QSZIZWHABNDXOK-MKYOLNSUSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50631493
|
Local ready
Direct docking supported
|
|
E3L064353
BDB064353
|
BDBM50631494
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3ccc(Cl)cc32)[C@@H](c2cccc(Cl)c2Cl)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H36Cl3N3O4 645.027000 |
RHJXGCAFKFZCLB-HNZCNSHZSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631494
|
Local ready
Direct docking supported
|
|
E3L064354
BDB064354
|
BDBM50631495
CCN1[C@@H](CC(C)(C)C)[C@@]2(CNc3cc(Cl)ccc32)[C@@H](c2cccc(Cl)c2)[C@@H]1C(=O)Nc1ccc(C(=O)O)cc1OC
|
C33H37Cl2N3O4 610.582000 |
AJQDQXYTMUFRRF-MKYOLNSUSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM50631495
|
Local ready
Direct docking supported
|
|
E3L064355
BDB064355
|
BDBM50631529
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CNC(=O)c2ccc(F)c(-c3ccc(N4C[C@@H](C)N(C)[C@@H](C)C4)c(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c3)c2)C(C)(C)C)cc1
|
C52H59F4N9O7S 1030.159000 |
HBHSDSLZXDASLT-FLKKWHKHSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB
BindingDB:BDBM50631529
|
Local ready
Direct docking supported
|
|
E3L064356
BDB064356
|
BDBM50631530
COc1cc(CN2Cc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1
|
C29H29FN4O3 500.574000 |
GTGSQXJNKTZDSD-UHFFFAOYSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM50631530; PubChem:CID172471808
|
Local ready
Direct docking supported
|
|
E3L064357
BDB064357
|
BDBM50631531
COc1cc(CN2CCCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1
|
C31H33FN4O3 528.628000 |
FVAXSVKVQVTTEZ-UHFFFAOYSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM50631531; PubChem:CID147573741
|
Local ready
Direct docking supported
|
|
E3L064358
BDB064358
|
BDBM50631532
COc1cc(CN2COc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1
|
C29H29FN4O4 516.573000 |
ORUSYCGZISHLQU-UHFFFAOYSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM50631532; PubChem:CID172442286
|
Local ready
Direct docking supported
|
|
E3L064359
BDB064359
|
BDBM50631533
COc1cc(Cn2cnc3c(-c4ccc(F)cc4C)cc(Cn4ccn(C)c4=N)cc3c2=O)cc(OC)c1
|
C29H28FN5O3 513.573000 |
XUJQZQBHCJAMSU-UHFFFAOYSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM50631533; PubChem:CID155382150
|
Local ready
Direct docking supported
|
|
E3L064360
BDB064360
|
BDBM50631534
COc1cc(CN2CNc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1
|
C29H30FN5O3 515.589000 |
BKDGXFQGTYBNAT-UHFFFAOYSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM50631534; PubChem:CID155382244
|
Local ready
Direct docking supported
|