| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L064381
BDB064381
|
BDBM50631622
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)N1CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC1)c1nnc(C)n1-2
|
C37H36ClN7O4S 710.260000 |
WXSOTMXNHJTFKS-XLTVJXRZSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631622
|
Local ready
Direct docking supported
|
|
E3L064382
BDB064382
|
GSPT1 degrader-3
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN1CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC1)c1nnc(C)n1-2
|
C39H41ClN8O4S 753.329000 |
DQGNINFYAAEZKL-FSRLHOSWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM50631623; PubChem:CID170453132
|
Local ready
Direct docking supported
|
|
E3L064383
BDB064383
|
BDBM50631624
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCN1CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC1)c1nnc(C)n1-2
|
C40H43ClN8O4S 767.356000 |
ZCOPIRBPZIGHDU-CYZZXXEPSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631624
|
Local ready
Direct docking supported
|
|
E3L064384
BDB064384
|
BDBM50631625
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCN1CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC1)c1nnc(C)n1-2
|
C41H45ClN8O4S 781.383000 |
FOTJPEPDXXOTQF-JEFWXSHNSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631625
|
Local ready
Direct docking supported
|
|
E3L064385
BDB064385
|
BDBM50631626
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCN1CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC1)c1nnc(C)n1-2
|
C42H47ClN8O4S 795.410000 |
OJBZGRZGVKAUHH-CDRRMRQFSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631626
|
Local ready
Direct docking supported
|
|
E3L064386
BDB064386
|
BDBM50631627
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCN1CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC1)c1nnc(C)n1-2
|
C43H49ClN8O4S 809.437000 |
OKISKGIPUPRZPL-SFCXHYMASA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631627
|
Local ready
Direct docking supported
|
|
E3L064387
BDB064387
|
BDBM50631628
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)Nc1ccc(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc1)c1nnc(C)n1-2
|
C39H34ClN7O4S 732.266000 |
NAJLKAMZDMZECA-FSRLHOSWSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631628
|
Local ready
Direct docking supported
|
|
E3L064388
BDB064388
|
BDBM50631629
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCNc1ccc(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc1)c1nnc(C)n1-2
|
C41H39ClN8O4S 775.335000 |
SGHSUUSYNYZHKK-JEFWXSHNSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631629
|
Local ready
Direct docking supported
|
|
E3L064389
BDB064389
|
BDBM50631630
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCNc1ccc(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc1)c1nnc(C)n1-2
|
C42H41ClN8O4S 789.362000 |
BNZBBHXKCFPTND-CDRRMRQFSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631630
|
Local ready
Direct docking supported
|
|
E3L064390
BDB064390
|
BDBM50631631
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCNc1ccc(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc1)c1nnc(C)n1-2
|
C43H43ClN8O4S 803.389000 |
MFAVXSAHTAKLRF-SFCXHYMASA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631631
|
Local ready
Direct docking supported
|
|
E3L064391
BDB064391
|
BDBM50631632
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCNc1ccc(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc1)c1nnc(C)n1-2
|
C44H45ClN8O4S 817.416000 |
GUKINEBETXGZNQ-TYIYNAFKSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631632
|
Local ready
Direct docking supported
|
|
E3L064392
BDB064392
|
BDBM50631633
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCNc1ccc(Cc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4)cc1)c1nnc(C)n1-2
|
C45H47ClN8O4S 831.443000 |
JCFHQNJZGSNYNS-NWDJCJOJSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631633
|
Local ready
Direct docking supported
|
|
E3L064393
BDB064393
|
BDBM50631634
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN1CCC3(CCC(c4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)CC1)c1nnc(C)n1-2
|
C44H49ClN8O4S 821.448000 |
ZKMPZGMDXOECHS-SFCXHYMASA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631634
|
Local ready
Direct docking supported
|
|
E3L064394
BDB064394
|
BDBM50631635
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN1CC3(CCC(c4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)C1)c1nnc(C)n1-2
|
C42H45ClN8O4S 793.394000 |
JFSVSFBLGUFRRC-JEFWXSHNSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631635
|
Local ready
Direct docking supported
|
|
E3L064395
BDB064395
|
BDBM50631636
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN1CC(N3CCC(c4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)C1)c1nnc(C)n1-2
|
C42H46ClN9O4S 808.409000 |
LHUVKOFLIPGEIS-CDRRMRQFSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50631636
|
Local ready
Direct docking supported
|
|
E3L064396
BDB064396
|
N-(2,6-dioxopiperidin-3-yl)-2-phenylacetamide
O=C1CCC(NC(=O)Cc2ccccc2)C(=O)N1
|
C13H14N2O3 246.266000 |
OQGRFQCUGLKSAV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM50631797; PubChem:CID157096
|
Local ready
Direct docking supported
|
|
E3L064397
BDB064397
|
Pyroglutamylbenzylamide
O=C1CC[C@@H](C(=O)NCc2ccccc2)N1
|
C12H14N2O2 218.256000 |
MDCKMKIRZIXFCH-JTQLQIEISA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM50631798; PubChem:CID137348
|
Local ready
Direct docking supported
|
|
E3L064398
BDB064398
|
N-benzyl-5-oxo-D-prolinamide
O=C1CC[C@H](C(=O)NCc2ccccc2)N1
|
C12H14N2O2 218.256000 |
MDCKMKIRZIXFCH-SNVBAGLBSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM50631799; PubChem:CID7034154
|
Local ready
Direct docking supported
|
|
E3L064399
BDB064399
|
BDBM50631800
CN1C(=O)CCC(N2Cc3ccc(S(=O)(=O)F)cc3C2=O)C1=O
|
C14H13FN2O5S 340.332000 |
AMHYHMMSUWYWOK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM50631800; PubChem:CID172451463
|
Local ready
Direct docking supported
|
|
E3L064400
BDB064400
|
BDBM50631802
O=C1CCC(NC(=O)Cc2cccc(S(=O)(=O)F)c2)C(=O)N1
|
C13H13FN2O5S 328.321000 |
LWEWTHYJTCCIIF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM50631802; PubChem:CID172440969
|
Local ready
Direct docking supported
|