| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L065970
LIG000540
|
17
Nc1cccc2c1ncn2C1CCC(=O)NC1=O
|
C12H12N4O2 244.254000 |
HJIALHKCRPBMOA-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB829
|
Local ready
Direct docking supported
|
|
E3L065971
LIG000541
|
22o
CC(C)(C)c1cccc(NC(=O)NCc2ccc3nnn(C4CCC(=O)NC4=O)c(=O)c3c2)c1
|
C24H26N6O4 462.510000 |
HJPYOJYWYVMTJO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB82
|
Local ready
Direct docking supported
|
|
E3L065972
LIG000542
|
ZXH-2-093
O=C1CCC(N2Cc3c(Nc4ccnc(Nc5ccc6c(c5)Cc5ccccc5-6)n4)cccc3C2=O)C(=O)N1
|
C30H24N6O3 516.561000 |
HJQUHGOGBFRLIP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1141
|
Local ready
Direct docking supported
|
|
E3L065973
LIG000543
|
QXG-131-6
Cc1c(C(=O)Nc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)nc2ccccn12
|
C22H19N5O4 417.425000 |
HJVNRBFXIXENJT-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB235
|
Local ready
Direct docking supported
|
|
E3L065975
LIG000545
|
31
CC[C@H](CO)Nc1nc(NCc2ccc(-c3cn[nH]c3)cc2)c2ncn(C(C)C)c2n1
|
C22H28N8O 420.521000 |
HKKCGSDYVXEOHM-GOSISDBHSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB213
|
Local ready
Direct docking supported
|
|
E3L065976
LIG000546
|
SJ0040
Cc1cccc(C(=O)Nc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)c1
|
C21H19N3O4 377.400000 |
HKQXTORGXDGFIQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB302
|
Local ready
Direct docking supported
|
|
E3L065978
LIG000548
|
FL6
O=C1CCC(c2cccc(OS(=O)(=O)F)c2)C(=O)N1
|
C11H10FNO5S 287.268000 |
HKTFEELTLCEILT-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB926
|
Local ready
Direct docking supported
|
|
E3L065979
LIG000549
|
ZZ7-16-020
CC(C)S(=O)(=O)c1ccccc1Nc1nc(NC2CN(C(=O)c3ccccc3)C2)ncc1Cl
|
C23H24ClN5O3S 485.997000 |
HKXWKJUWASESPO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB179
|
Local ready
Direct docking supported
|
|
E3L065980
LIG000550
|
R9
O=C1CCC(NC(=O)c2cccc3cc[nH]c23)C(=O)N1
|
C14H13N3O3 271.276000 |
HLIFKZPFEAXHSQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1389
|
Local ready
Direct docking supported
|
|
E3L065981
LIG000551
|
8
CC[C@H](CO)Nc1nc(NCc2ccc(-c3ccc(O)cn3)cc2)c2ncn(C(C)C)c2n1
|
C24H29N7O2 447.543000 |
HMFHGGLGKHMQPW-GOSISDBHSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB218
|
Local ready
Direct docking supported
|
|
E3L065982
LIG000552
|
9r
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCN(C(=O)/C=C/C(=O)c7ccc(Br)cc7)CC6)c(C(F)(F)F)c5)c4c3c2)cn1
|
C36H27BrF3N7O4 758.555000 |
HMMVSBOUNVPJOS-ACCUITESSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB667
|
Local ready
Direct docking supported
|
|
E3L065983
LIG000553
|
LIG000553
O=C1CCC(N2Cc3ccc(F)cc3C2=O)C(=O)N1
|
C13H11FN2O3 262.240000 |
HNAQSGYWVZTYEF-UHFFFAOYSA-N | Q96SW2 | - |
e3_ligand
e3_ligand:169
|
Local ready
Direct docking supported
|
|
E3L065984
LIG000554
|
LL-K12-10
CCn1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(N3CCN(C(=O)c4ccncc4)CC3)nc21
|
C25H24Cl2N10O 551.442000 |
HNNHEQRZNFLUHK-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB468
|
Local ready
Direct docking supported
|
|
E3L065985
LIG000555
|
21b
O=C1CCC(N2Cc3cc(C4=C[C@@]4(COOCC(Cl)(Cl)Cl)c4ccc(Br)cc4)ccc3C2=O)C(=O)N1
|
C25H20BrCl3N2O5 614.707000 |
HNNUQHAIWLOKQD-PIFIWZBESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1165
|
Local ready
Direct docking supported
|
|
E3L065986
LIG000556
|
MRT-2359
O=C1CCC(N2Cc3ccc(COC(=O)Nc4cc(OC(F)(F)F)ccc4F)cc3C2=O)C(=O)N1
|
C22H17F4N3O6 495.385000 |
HNTGMIGBGVFOBT-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM654045; MolGlueDB:MGDB1241
|
Local ready
Direct docking supported
|
|
E3L065988
LIG000558
|
6b
O=C1CCC(NC(=O)c2cc(F)c(F)c(F)c2F)C(=O)N1
|
C12H8F4N2O3 304.199000 |
HOAHVHODYFOOBF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630589; MolGlueDB:MGDB902
|
Local ready
Direct docking supported
|
|
E3L065989
LIG000559
|
DS28(S-CR8)
CC[C@@H](CO)Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1
|
C24H29N7O 431.544000 |
HOCBJBNQIQQQGT-IBGZPJMESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1600
|
Local ready
Direct docking supported
|
|
E3L065990
LIG000560
|
CR8
CC[C@H](CO)Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1
|
C24H29N7O 431.544000 |
HOCBJBNQIQQQGT-LJQANCHMSA-N | P51948 | Cyclin-H |
BindingDB, MolGlueDB
BindingDB:BDBM50154937; MolGlueDB:MGDB204
|
Local ready
Direct docking supported
|
|
E3L065993
LIG000563
|
9c
C=CC(=O)N1CCN(c2ccc(-n3nnc4c(=O)[nH]c5ccc(-c6ccc(OC)nc6)cc5c43)cc2C(F)(F)F)CC1
|
C29H24F3N7O3 575.551000 |
HPGCMTZBARIUGP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB32
|
Local ready
Direct docking supported
|
|
E3L065994
LIG000564
|
11b
Nc1ccc(C(=O)NC2CCC(=O)NC2=O)c(C(F)(F)F)c1
|
C13H12F3N3O3 315.251000 |
HPKPRXOHNCNKLQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630597; MolGlueDB:MGDB797
|
Local ready
Direct docking supported
|