| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066037
LIG000607
|
Compound 4
CC(C)(C)Nc1c(-c2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)nc2ccccn12
|
C24H23N5O4 445.479000 |
IEPVLXVJCUHDAW-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB98
|
Local ready
Direct docking supported
|
|
E3L066038
LIG000608
|
ZXH-1-102
O=C1CCC(N2Cc3c(NC(=O)CNc4ccnc(NCCCN5CCCC5=O)n4)cccc3C2=O)C(=O)N1
|
C26H30N8O5 534.577000 |
IEXDTTWEGFWSTO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM585779; MolGlueDB:MGDB1138
|
Local ready
Direct docking supported
|
|
E3L066039
LIG000609
|
LYG-207
CO/N=C(/C(=O)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O)c1ccc(F)cc1
|
C23H21FN4O5 452.442000 |
IEXKJKQCNYRFKZ-NHFJDJAPSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1334
|
Local ready
Direct docking supported
|
|
E3L066040
LIG000610
|
Compound 1
CC(C)(C)Nc1c(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)nc2ccccn12
|
C24H25N5O3 431.496000 |
IFLAYQIAAFCPNM-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB99
|
Local ready
Direct docking supported
|
|
E3L066041
LIG000611
|
Compound 7
O=C1CCC(N2Cc3cc(-c4nc5ccccn5c4Cl)ccc3C2=O)C(=O)N1
|
C20H15ClN4O3 394.818000 |
IFOJCWBSMSYHLB-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1161
|
Local ready
Direct docking supported
|
|
E3L066042
LIG000612
|
1D
O=C1CCC(N2Cc3c(cccc3N3CCCCC3)C2=O)C(=O)N1
|
C18H21N3O3 327.384000 |
IFPUAXTUZWDGME-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1094
|
Local ready
Direct docking supported
|
|
E3L066043
LIG000613
|
6c
O=C1CCC(N2Cc3c(C#CCNCCc4ccccc4)cccc3C2=O)C(=O)N1
|
C24H23N3O3 401.466000 |
IGAWZWZFBBCASC-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1367
|
Local ready
Direct docking supported
|
|
E3L066044
LIG000614
|
DS25
CC[C@H](CO)Nc1nc(NCc2ccc(-c3ccc(C)s3)cc2)c2ncn(C(C)C)c2n1
|
C24H30N6OS 450.612000 |
IGJPGKABXPANSO-LJQANCHMSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1572
|
Local ready
Direct docking supported
|
|
E3L066045
LIG000615
|
LIG000615
CN1CCc2cc3c(cc2CC1)C(=O)N(C1CCC(=O)NC1=O)C3=O
|
C18H19N3O4 341.367000 |
IGNGENZEPWGVQG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, e3_ligand
BindingDB:BDBM50628763; e3_ligand:88
|
Local ready
Direct docking supported
|
|
E3L066046
LIG000616
|
7
CCN1C[C@H](Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC[C@H]1C
|
C21H27N3O4 385.464000 |
IHBGNCYMSRWSLK-HZBOCPGUSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB464
|
Local ready
Direct docking supported
|
|
E3L066047
LIG000617
|
6
CCN1C[C@H](Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC[C@@H]1C
|
C21H27N3O4 385.464000 |
IHBGNCYMSRWSLK-NHSXVPOTSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB463
|
Local ready
Direct docking supported
|
|
E3L066048
LIG000618
|
AN5382
Cc1nc2ccccc2cc1C(=O)N/N=C/c1cccc(Cl)c1
|
C18H14ClN3O 323.783000 |
IHUOVSIGQDWEFD-RGVLZGJSSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB415
|
Local ready
Direct docking supported
|
|
E3L066049
LIG000619
|
Z5112057389
Cn1nc(C2CCC(=O)NC2=O)c2ccc(NS(=O)(=O)c3ccc(OCC(=O)O)cc3)cc21
|
C21H20N4O7S 472.479000 |
IHYVEPILNJFXSN-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB588
|
Local ready
Direct docking supported
|
|
E3L066050
LIG000620
|
Br-Le
Nc1cc(Br)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C13H12BrN3O3 338.161000 |
IIAHEYPYLVKWSS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB789
|
Local ready
Direct docking supported
|
|
E3L066051
LIG000621
|
8
Nc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C13H11N3O4 273.248000 |
IICWMVJMJVXCLY-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1, Protein cereblon |
BindingDB, e3_ligand, MolGlueDB
BindingDB:BDBM511643; e3_ligand:58; MolGlueDB:MGDB809
|
Local ready
Direct docking supported
|
|
E3L066053
LIG000623
|
73
CC(C)(C)C(=O)Nc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C18H19N3O5 357.366000 |
IIEULSMTXBBDEI-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB81
|
Local ready
Direct docking supported
|
|
E3L066054
LIG000624
|
ZXH-1-172
O=C1CCC(N2Cc3c(NC4=NC(c5ccc(-c6ccccc6)cc5)NC=C4)cccc3C2=O)C(=O)N1
|
C29H25N5O3 491.551000 |
IINCMRZQJSMQAO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1147
|
Local ready
Direct docking supported
|
|
E3L066055
LIG000625
|
dALK-10
Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCN(CCCC(=O)N2CCN(c3cc4c(cc3F)C(=O)N(C3CCC(=O)NC3=O)C4=O)CC2)CC1
|
C49H57ClFN9O8S 986.568000 |
IJORPZSGPJIUMV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB279
|
Local ready
Direct docking supported
|
|
E3L066056
LIG000626
|
16
O=C1CCC(N2Cc3cc(NC(=O)c4cccc(F)c4)ccc3C2=O)C(=O)N1
|
C20H16FN3O4 381.363000 |
IKDBDJNITQUCOU-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1060
|
Local ready
Direct docking supported
|
|
E3L066057
LIG000627
|
4
COC(=O)c1ccc2c(c1)[nH]c1nc(Cc3ccccc3)nc(N[C@H]3CC[C@H](N(C)C)CC3)c12
|
C27H31N5O2 457.578000 |
IKEJMWQWQFLJOV-MXVIHJGJSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1412
|
Local ready
Direct docking supported
|