| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L065995
LIG000565
|
22m
Cc1ccc(NC(=O)NCc2ccc3nnn(C4CCC(=O)NC4=O)c(=O)c3c2)cc1C
|
C22H22N6O4 434.456000 |
HPMZWBGZHIEYEF-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB241
|
Local ready
Direct docking supported
|
|
E3L065996
LIG000566
|
11a
C[C@H]1C[C@@H](N(C)C)CN(c2ncc(Cl)c(Nc3ccc4c(c3)c3c(c(=O)n4C)OCC(F)(F)[C@@H](C4CC4)N3)n2)C1
|
C28H34ClF2N7O2 574.076000 |
HPQGUGFUKNXBFU-PQNFPLSNSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB25
Related BindingDB:BDBM50606289; Related BindingDB:BDBM50606288
|
Local ready
Direct docking supported
|
|
E3L065997
LIG000567
|
I6
CCCn1c(=O)c(C#N)nn(-c2ccc(C)c(C)c2)c1=O
|
C15H16N4O2 284.319000 |
HQHRJYSXSJSNSB-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB455
|
Local ready
Direct docking supported
|
|
E3L065998
LIG000568
|
12-60
Cn1c(C2CC2)nc2cnc(Nc3ccc(N4CCN(C(=O)C5CCN(C6CN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)C6)CC5)CC4)cc3)nc21
|
C41H45N11O5 771.883000 |
HQIGKYXFCKTMMT-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1480
|
Local ready
Direct docking supported
|
|
E3L065999
LIG000569
|
ZXH-1-137
O=C1CCC(N2Cc3c(NC(=O)CNc4ccnc(N5CCC[C@@H]5CO)n4)cccc3C2=O)C(=O)N1
|
C24H27N7O5 493.524000 |
HQIHAVBDCVQJOE-IKJXHCRLSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50541817; MolGlueDB:MGDB1132
|
Local ready
Direct docking supported
|
|
E3L066000
LIG000570
|
ZXH-1-090
O=C1CCC(N2Cc3c(NC(=O)CNc4ccnc(N5CCC[C@H]5CO)n4)cccc3C2=O)C(=O)N1
|
C24H27N7O5 493.524000 |
HQIHAVBDCVQJOE-PIVQAISJSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM585777; MolGlueDB:MGDB1133
|
Local ready
Direct docking supported
|
|
E3L066001
LIG000571
|
27
COc1cccc2cc(CNc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)ccc12
|
C25H23N3O4 429.476000 |
HQPVSNNDCCRACJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB629
|
Local ready
Direct docking supported
|
|
E3L066002
LIG000572
|
7
O=C1CCC(N2Cc3cc(NCc4ccc5oc6ccccc6c5c4)ccc3C2=O)C(=O)N1
|
C26H21N3O4 439.471000 |
HQXKVSGFXIECPG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1222
|
Local ready
Direct docking supported
|
|
E3L066003
LIG000573
|
QXG-131-2
COc1ccc2nc(C(=O)Nc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cn2c1
|
C22H19N5O5 433.424000 |
HRVOVFAJNZWSIH-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB746
|
Local ready
Direct docking supported
|
|
E3L066005
LIG000575
|
UPD-Glucose
O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O[C@H]3OC(CO)[C@@H](O)C(O)C3O)C(O)C2O)c(=O)[nH]1
|
C15H24N2O17P2 566.302000 |
HSCJRCZFDFQWRP-BQIVXCFRSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB892
|
Local ready
Direct docking supported
|
|
E3L066006
LIG000576
|
6
CC[C@H](CO)Nc1nc(NCc2ccc(-c3ccc(F)cn3)cc2)c2ncn(C(C)C)c2n1
|
C24H28FN7O 449.534000 |
HSGZPNNDFKSLEA-LJQANCHMSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB217
|
Local ready
Direct docking supported
|
|
E3L066007
LIG000577
|
DS03
CCCCc1ccc(CNc2nc(N[C@H](CC)CO)nc3c2ncn3C(C)C)cc1
|
C23H34N6O 410.566000 |
HSQCITPGWHALIF-LJQANCHMSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1585
|
Local ready
Direct docking supported
|
|
E3L066008
LIG000578
|
LYG-302
COc1cc2cc(C(=O)NCc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)[se]c2cc1OC
|
C25H23N3O6Se 540.434000 |
HSYMKSQDIUYEIP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1336
|
Local ready
Direct docking supported
|
|
E3L066009
LIG000579
|
ML 1-15
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)Nc1ccc3c(=O)oc(=O)[nH]c3c1)c1nnc(C)n1-2
|
C27H21ClN6O4S 561.023000 |
HUIZURVCNVCLSA-FQEVSTJZSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB257
|
Local ready
Direct docking supported
|
|
E3L066010
LIG000580
|
12
Nc1n[nH]c2c(CN3CCCC3)cc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nc12
|
C24H25N7O3 459.510000 |
HUZLPHWJLUUHAZ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1503
|
Local ready
Direct docking supported
|
|
E3L066011
LIG000581
|
9a
Cc1ccc(NC(=O)CCc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1Cl
|
C23H22ClN3O4 439.899000 |
HVGVXTMIJBEFSO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB336
|
Local ready
Direct docking supported
|
|
E3L066012
LIG000582
|
LIG000582
CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(C(C)(C)C)cc1)C(C)(C)C
|
C25H39N3O4 445.604000 |
HWRVUOLZBZRHRB-PSMQTCRGSA-N | P40337 | - |
e3_ligand
e3_ligand:22
|
Local ready
Direct docking supported
|
|
E3L066013
LIG000583
|
15
Nc1cccc(N[C@@H]2CCC(=O)NC2=O)c1
|
C11H13N3O2 219.244000 |
HWWKOVGSUZFLBU-SECBINFHSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB817
|
Local ready
Direct docking supported
|
|
E3L066014
LIG000584
|
11
Nc1cccc(NC2CCC(=O)NC2=O)c1
|
C11H13N3O2 219.244000 |
HWWKOVGSUZFLBU-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB820
|
Local ready
Direct docking supported
|
|
E3L066015
LIG000585
|
14
Nc1cccc(N[C@H]2CCC(=O)NC2=O)c1
|
C11H13N3O2 219.244000 |
HWWKOVGSUZFLBU-VIFPVBQESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB818
|
Local ready
Direct docking supported
|