| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066741
LIG001311
|
SJ6986
O=C1CCC(N2C(=O)c3ccc(NS(=O)(=O)c4ccccc4OC(F)(F)F)cc3C2=O)C(=O)N1
|
C20H14F3N3O7S 497.407000 |
RKAFYSIKAVFVPS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM669519; MolGlueDB:MGDB1014
|
Local ready
Direct docking supported
|
|
E3L066742
LIG001312
|
LIG001312
Cc1nc2ccccc2c(=O)n1C1CCC(=O)NC1=O
|
C14H13N3O3 271.276000 |
RKAGXGJVJCKBPG-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB, e3_ligand
BindingDB:BDBM511644; e3_ligand:152
|
Local ready
Direct docking supported
|
|
E3L066743
LIG001313
|
7
CC(C)(O)c1cc2nn(CCCCCNCCCNc3cccc4c3C(=O)N(C3CCC(=O)NC3=O)C4=O)cc2cc1NC(=O)c1cccc(C(F)(F)F)n1
|
C38H41F3N8O6 762.790000 |
RKDBBXGRXIYXMB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50639835; MolGlueDB:MGDB127
|
Local ready
Direct docking supported
|
|
E3L066744
LIG001314
|
34e
CC(NC(=O)Nc1cccc(-c2ccccc2)c1)c1ccc2nnn(C3CCC(=O)NC3=O)c(=O)c2c1
|
C27H24N6O4 496.527000 |
RKJREIMDGKHZEZ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB184
|
Local ready
Direct docking supported
|
|
E3L066745
LIG001315
|
LL-K12-4
CCn1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(N3CCN(C(C)=O)CC3)nc21
|
C21H23Cl2N9O 488.383000 |
RKNNPLKDFGDCAJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB472
|
Local ready
Direct docking supported
|
|
E3L066746
LIG001316
|
QXG-1323
O=C1CCC(N2Cc3cc(NC(=O)c4cnc5ccccc5n4)ccc3C2=O)C(=O)N1
|
C22H17N5O4 415.409000 |
RKVSIVQGWAFNJW-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1062
|
Local ready
Direct docking supported
|
|
E3L066748
LIG001318
|
14w
O=C1CCC(CSc2ccccc2C(=O)O)C(=O)N1
|
C13H13NO4S 279.317000 |
RLSRLYVKQYQEJV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB941
|
Local ready
Direct docking supported
|
|
E3L066749
LIG001319
|
CM-2
O=C1CCC(N2Cc3c(OCCCC(=O)N4CCCc5ccccc54)cccc3C2=O)C(=O)N1
|
C26H27N3O5 461.518000 |
RLTDCECVFNMASN-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1453
|
Local ready
Direct docking supported
|
|
E3L066750
LIG001320
|
53
O=C1CCC(N2C(=O)c3cccc(-c4cc5ccccc5s4)c3C2=O)C(=O)N1
|
C21H14N2O4S 390.420000 |
RLYZXAUKZSXFDV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1021
|
Local ready
Direct docking supported
|
|
E3L066751
LIG001321
|
18
O=C1CCC(N2Cc3cc(CNC(=O)Nc4ccc(Cl)cc4Cl)ccc3C2=O)C(=O)N1
|
C21H18Cl2N4O4 461.305000 |
RMCSISWOQSSDHG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1181
|
Local ready
Direct docking supported
|
|
E3L066752
LIG001322
|
37
CCOc1ccc2cc(C(=O)Nc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)ccc2c1
|
C26H23N3O5 457.486000 |
RMDIWTMEVMFWCD-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB500
|
Local ready
Direct docking supported
|
|
E3L066753
LIG001323
|
5O
Cn1c(=O)n(C2CCC(=O)NC2=O)c2cccc(Br)c21
|
C13H12BrN3O3 338.161000 |
RMODNRAIBFTCEC-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB543
|
Local ready
Direct docking supported
|
|
E3L066754
LIG001324
|
D3
O=c1c(-c2ccccn2)cn(Cc2ccccc2)c(=O)n1Cc1ccccc1
|
C23H19N3O2 369.424000 |
RMULPOPAACYLFW-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB891
|
Local ready
Direct docking supported
|
|
E3L066755
LIG001325
|
T11
O=C(COCCOCCOCc1ccccc1)NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C27H29N3O8 523.542000 |
RNBQLFGIDLXHCT-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB875
|
Local ready
Direct docking supported
|
|
E3L066756
LIG001326
|
QXG-131-1
COc1ccn2cc(C(=O)Nc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nc2c1
|
C22H19N5O5 433.424000 |
RNEWLPVIZSSIKR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB741
|
Local ready
Direct docking supported
|
|
E3L066758
LIG001328
|
ZXH-2-133
COc1ccccc1C1N=C(Nc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)c2nc[nH]c2N1
|
C25H23N7O4 485.504000 |
RNLLWLRACTUXRL-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB715
|
Local ready
Direct docking supported
|
|
E3L066759
LIG001329
|
TX-16
CN1Cc2cc3c(cc2C1)C(=O)N(C1CCC(=O)NC1=O)C3=O
|
C16H15N3O4 313.313000 |
RNXFHBLKGAWWBL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, e3_ligand
BindingDB:BDBM50628761; e3_ligand:126
|
Local ready
Direct docking supported
|
|
E3L066760
LIG001330
|
DS09
CC[C@H](CO)Nc1nc(NCCCCc2ccccc2)c2ncn(C(C)C)c2n1
|
C22H32N6O 396.539000 |
ROGNKYQZCSTSTF-GOSISDBHSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1566
|
Local ready
Direct docking supported
|
|
E3L066761
LIG001331
|
Z5000146291
O=C1CCC(N2Cc3cc(NS(=O)(=O)c4cccc5ccoc45)ccc3C2=O)C(=O)N1
|
C21H17N3O6S 439.449000 |
ROGPPQPCAUZVKQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1234
|
Local ready
Direct docking supported
|
|
E3L066762
LIG001332
|
SAB355
CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(CC(=O)NCCOCCOCCOCC(=O)Nc5cccc6c5CN(C5CCC(=O)NC5=O)C6=O)CC4)cn3)nc2n(C2CCCC2)c1=O
|
C47H57N11O10 936.040000 |
ROGURJAGCVFXED-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB40
|
Local ready
Direct docking supported
|