| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066721
LIG001291
|
AN5602
Cc1ccc2nc(C)c(C(=O)N/N=C/c3cccnc3)cc2c1
|
C18H16N4O 304.353000 |
QZXAQKBCLSVYCJ-RGVLZGJSSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB372
|
Local ready
Direct docking supported
|
|
E3L066722
LIG001292
|
13
CC(C)(c1ccc(OCC2CCN(C(=O)CCCCCCOc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4=O)CC2)cc1)c1ccc(OC[C@H](O)CCl)cc1
|
C44H52ClN3O9 802.365000 |
RADMJLLCVISLHZ-NMKCAVOUSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1544
|
Local ready
Direct docking supported
|
|
E3L066723
LIG001293
|
LIG001293
O=C1CCN(Cc2ccccc2)C(=O)N1
|
C11H12N2O2 204.229000 |
RAGSBUDIXSABRI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, e3_ligand
BindingDB:BDBM581734; e3_ligand:159
|
Local ready
Direct docking supported
|
|
E3L066724
LIG001294
|
10
O=C1CCC(n2cc(-c3cscc3OCC3CCCCC3)nn2)C(=O)N1
|
C18H22N4O3S 374.466000 |
RBXFEJBRBRJAJN-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1303
|
Local ready
Direct docking supported
|
|
E3L066725
LIG001295
|
HQ005
Cc1cnc(NC(=O)Cc2csc(Nc3cccc(CO)n3)n2)s1
|
C15H15N5O2S2 361.452000 |
RCCDIUZAPKBQLV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB397
|
Local ready
Direct docking supported
|
|
E3L066726
LIG001296
|
27
CC(C)(C)OC(=O)N1CCN(c2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)CC1
|
C22H26N4O6 442.472000 |
RCYJUXUDJQXBGQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB111
|
Local ready
Direct docking supported
|
|
E3L066727
LIG001297
|
Z5000147289
N#Cc1sc2ccccc2c1S(=O)(=O)Nc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O
|
C22H16N4O5S2 480.527000 |
RDCPKDRCKZJZEG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB759
|
Local ready
Direct docking supported
|
|
E3L066728
LIG001298
|
6e
COc1cc2onc(C)c2cc1NS(=O)(=O)c1cc(Br)ccc1OCC(=O)NCCCCCCNC(=O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C38H39BrN6O12S 883.731000 |
RDTNUMAXRGUTHB-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB726
|
Local ready
Direct docking supported
|
|
E3L066729
LIG001299
|
74
COc1cccc2c1C=C(C(=O)Nc1ccc3c(c1)CN(C1CCC(=O)NC1=O)C3=O)CO2
|
C24H21N3O6 447.447000 |
RFENVQIDXQQDHS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB627
|
Local ready
Direct docking supported
|
|
E3L066730
LIG001300
|
27
Cc1ccc(N2CCCN(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2=O)cc1Cl
|
C25H25ClN4O4 480.952000 |
RGAAYOOQOATZEL-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB286
|
Local ready
Direct docking supported
|
|
E3L066731
LIG001301
|
ALV-07-037-01
CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(CCOCCOCCOc5cccc(CN6CCC(c7ccc8c(c7)CN(C7CCC(=O)NC7=O)C8=O)CC6)c5)CC4)cn3)nc2n(C2CCCC2)c1=O
|
C55H66N10O8 995.195000 |
RGRLZYQCVJDBHO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1526
|
Local ready
Direct docking supported
|
|
E3L066732
LIG001302
|
Z4871545631
Cc1ccc(NC2CCC(=O)NC2=O)c(Cl)c1
|
C12H13ClN2O2 252.701000 |
RHENVMWAACMFML-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB359
|
Local ready
Direct docking supported
|
|
E3L066733
LIG001303
|
75
O=C1CCC(N2C(=O)c3ccc(NC(=O)C4CCC4)cc3C2=O)C(=O)N1
|
C18H17N3O5 355.350000 |
RHHPPTURSOAPQY-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB962
|
Local ready
Direct docking supported
|
|
E3L066734
LIG001304
|
80
O=C1CCC(N2C(=O)c3ccc(NC(=O)c4cnccn4)cc3C2=O)C(=O)N1
|
C18H13N5O5 379.332000 |
RHKNLWRBBYVMMD-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB960
|
Local ready
Direct docking supported
|
|
E3L066735
LIG001305
|
dFKBP-1
CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(NC(=O)CCC(=O)NCCCCNC(=O)COc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)c1
|
C53H64N6O14 1009.123000 |
RIBCWKRMNKOGRN-GGJINPDOSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB429
|
Local ready
Direct docking supported
|
|
E3L066736
LIG001306
|
LIG001306
C#Cc1ccc([C@H](CC(=O)NC)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](c2cc(C)no2)C(C)C)cc1
|
C26H32N4O5 480.565000 |
RILDEXHTOOMQCV-MDAIXWLXSA-N | P40337 | - |
e3_ligand
e3_ligand:30
|
Local ready
Direct docking supported
|
|
E3L066737
LIG001307
|
MANT-uracil
CNc1ccccc1C(O)NCCN1CCC(=O)NC1O
|
C14H22N4O3 294.355000 |
RIPWUWMUOGSPBJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1395
|
Local ready
Direct docking supported
|
|
E3L066738
LIG001308
|
9n
COc1cccc(C(=O)/C=C/C(=O)N2CCN(c3ccc(-n4nnc5c(=O)[nH]c6ccc(-c7ccc(OC)nc7)cc6c54)cc3C(F)(F)F)CC2)c1
|
C37H30F3N7O5 709.685000 |
RIQCUPAYLATODD-ACCUITESSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB708
|
Local ready
Direct docking supported
|
|
E3L066739
LIG001309
|
21
Cn1nc(N)c2nc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc(CN3CCCC3)c21
|
C25H27N7O3 473.537000 |
RIRKNMJJINDXAY-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1512
|
Local ready
Direct docking supported
|
|
E3L066740
LIG001310
|
2
Cn1cc(-c2ccc3c(c2)[nH]c2nc(Cc4ccccc4)nc(N[C@H]4CC[C@H](N)CC4)c23)cn1
|
C27H29N7 451.578000 |
RKABSGYFBJREIG-MEMLXQNLSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1410
|
Local ready
Direct docking supported
|