| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066679
LIG001249
|
ML-1-25
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)Nc1cccc(C=O)n1)c1nnc(C)n1-2
|
C25H21ClN6O2S 505.003000 |
QKMBNYIDPAVNBM-IBGZPJMESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB258
|
Local ready
Direct docking supported
|
|
E3L066680
LIG001250
|
81
O=C1CCC(N2Cc3cc(NC(=O)C4=Cc5cc(Br)cc(Br)c5OC4)ccc3C2=O)C(=O)N1
|
C23H17Br2N3O5 575.213000 |
QKPKDXGPDMVCIR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1203
|
Local ready
Direct docking supported
|
|
E3L066681
LIG001251
|
65
O=C1CCC(N2C(=O)c3cccc(NC(=O)C4CCC4)c3C2=O)C(=O)N1
|
C18H17N3O5 355.350000 |
QLCVNSGPNQDWAY-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB979
|
Local ready
Direct docking supported
|
|
E3L066682
LIG001252
|
UOM-005433
O=C(CC12CC3CC(CC(C3)C1)C2)Nc1ncc(SCc2cccnc2)s1
|
C21H25N3OS2 399.585000 |
QLXYCWPLZTVMMV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1488
|
Local ready
Direct docking supported
|
|
E3L066683
LIG001253
|
EM12-SO2Pyr(3-CF3)
O=C1CCC(N2Cc3ccc(S(=O)(=O)n4ccc(C(F)(F)F)n4)cc3C2=O)C(=O)N1
|
C17H13F3N4O5S 442.375000 |
QLZSVRMOCPFVIB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630778; MolGlueDB:MGDB1249
|
Local ready
Direct docking supported
|
|
E3L066684
LIG001254
|
NRX-2663
O=C(O)c1cccc(NC(=O)c2c(Oc3ccccc3)cc(C(F)(F)F)[nH]c2=O)c1
|
C20H13F3N2O5 418.327000 |
QMARDTCIJVODCK-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB885
|
Local ready
Direct docking supported
|
|
E3L066685
LIG001255
|
HQ461
Cc1cccc(Nc2nc(CC(=O)Nc3ncc(C)s3)cs2)n1
|
C15H15N5OS2 345.453000 |
QMRBCNQCRMTXBE-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB377
|
Local ready
Direct docking supported
|
|
E3L066687
LIG001257
|
EM12-SO2-T
O=C1CCC(N2Cc3ccc(S(=O)(=O)n4ccc(=O)[nH]c4=O)cc3C2=O)C(=O)N1
|
C17H14N4O7S 418.387000 |
QMVALDXXRYVCCL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630781; MolGlueDB:MGDB1248
|
Local ready
Direct docking supported
|
|
E3L066688
LIG001258
|
Meisoindigo
CN1C(=O)/C(=C2/C(=O)Nc3ccccc32)c2ccccc21
|
C17H12N2O2 276.295000 |
QNOCRUSVMMAKSC-CCEZHUSRSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1495
|
Local ready
Direct docking supported
|
|
E3L066689
LIG001259
|
ZXH-2-059
O=C1CCC(N2Cc3c(Nc4ccnc(Nc5ccc6ccccc6c5)n4)cccc3C2=O)C(=O)N1
|
C27H22N6O3 478.512000 |
QOBMNLLXLIPVAY-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1142
|
Local ready
Direct docking supported
|
|
E3L066690
LIG001260
|
22n
CC(C)(C)c1ccc(NC(=O)NCc2ccc3nnn(C4CCC(=O)NC4=O)c(=O)c3c2)cc1
|
C24H26N6O4 462.510000 |
QOJDIXROHYFUFQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB86
|
Local ready
Direct docking supported
|
|
E3L066691
LIG001261
|
LIG001261
CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(Cl)cc1)C(C)(C)C
|
C21H30ClN3O4 423.941000 |
QORQDSURGXKKLU-PSMGESJCSA-N | P40337 | - |
e3_ligand
e3_ligand:17
|
Local ready
Direct docking supported
|
|
E3L066692
LIG001262
|
LIG001262
CNC(=O)C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](c1cc(C)no1)C(C)C)c1ccc(F)cc1
|
C24H31FN4O5 474.533000 |
QOVORLCCBWSWNE-MDPIYQRISA-N | P40337 | - |
e3_ligand
e3_ligand:34
|
Local ready
Direct docking supported
|
|
E3L066693
LIG001263
|
1F
CCOc1ccc(-c2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1
|
C21H20N2O4 364.401000 |
QPHBSODEKBKRQI-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB499
|
Local ready
Direct docking supported
|
|
E3L066694
LIG001264
|
LYG-417
Cc1cc2c(cc1Cl)C=C(C(=O)NCc1ccc3c(c1)CN(C1CCC(=O)NC1=O)C3=O)CO2
|
C25H22ClN3O5 479.920000 |
QPIABGBXDVLFIO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1360
|
Local ready
Direct docking supported
|
|
E3L066695
LIG001265
|
LIG001265
NC(=O)C[C@H](N)C(=O)N[C@H]1CC(=O)NC1=O
|
C8H12N4O4 228.208000 |
QPUVEHWNUSUPEG-IMJSIDKUSA-N | Q96SW2 | - |
e3_ligand
e3_ligand:112
|
Local ready
Direct docking supported
|
|
E3L066696
LIG001266
|
T15
O=C1CCC(N2C(=O)c3cccc(C(=O)NCCOCCOCCOCc4ccccc4)c3C2=O)C(=O)N1
|
C27H29N3O8 523.542000 |
QPWWJPRPPHFPDS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB971
|
Local ready
Direct docking supported
|
|
E3L066697
LIG001267
|
ML-1-43
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)N1CCN(C(=O)CON3C(=O)c4ccccc4C3=O)CC1)c1nnc(C)n1-2
|
C33H30ClN7O5S 672.167000 |
QQXBATYJWJKIBS-VWLOTQADSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB251
|
Local ready
Direct docking supported
|
|
E3L066698
LIG001268
|
LYG-102
O=C1CCC(N2Cc3cc(CNC(=O)/C(Cc4ccc(Cl)cc4)=N/O)ccc3C2=O)C(=O)N1
|
C23H21ClN4O5 468.897000 |
QRBUWHHVKWDOJJ-OVVQPSECSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1321
|
Local ready
Direct docking supported
|
|
E3L066699
LIG001269
|
20
O=C1CCC(N2C(=O)c3cccc(N4CCOCC4)c3C2=O)C(=O)N1
|
C17H17N3O5 343.339000 |
QRPGOAYGIOFBAV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1030
|
Local ready
Direct docking supported
|