| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L067368
LIG001938
|
LL-K12-3
CC(=O)N1CCN(c2nc(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)c3ncn(C)c3n2)CC1
|
C20H21Cl2N9O 474.356000 |
ZGDCDYWFGPFMSO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB66
|
Local ready
Direct docking supported
|
|
E3L067369
LIG001939
|
26
Cc1ccc(N(C)C(=O)N(C)Cc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1Cl
|
C24H25ClN4O4 468.941000 |
ZGEMXRIHLDHLSE-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB323
|
Local ready
Direct docking supported
|
|
E3L067370
LIG001940
|
51
O=C1CCC(N2C(=O)c3cccc(-c4cccnc4)c3C2=O)C(=O)N1
|
C18H13N3O4 335.319000 |
ZGSCNVAGVYLFRU-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1022
|
Local ready
Direct docking supported
|
|
E3L067371
LIG001941
|
7-OH-EM12
O=C1CCC(N2Cc3cccc(O)c3C2=O)C(=O)N1
|
C13H12N2O4 260.249000 |
ZHINEOZMGPJDNM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50614099; MolGlueDB:MGDB768
|
Local ready
Direct docking supported
|
|
E3L067372
LIG001942
|
9c
Cc1ccc(NC(=O)CCc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1Cl
|
C23H22ClN3O4 439.899000 |
ZHSKDNZFKUGRBS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB339
|
Local ready
Direct docking supported
|
|
E3L067373
LIG001943
|
LIG001943
CSCC[C@H](N)C(=O)N[C@H]1CC(=O)NC1=O
|
C9H15N3O3S 245.304000 |
ZIHBQYLVOWLNBB-WDSKDSINSA-N | Q96SW2 | - |
e3_ligand
e3_ligand:119
|
Local ready
Direct docking supported
|
|
E3L067374
LIG001944
|
(S)-ACE-OH
C[C@H](O)c1ccc2c(c1)N(CCCN(C)C)c1ccccc1S2
|
C19H24N2OS 328.481000 |
ZIJWCRNUEBJMSQ-AWEZNQCLSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB24
|
Local ready
Direct docking supported
|
|
E3L067375
LIG001945
|
(R)-ACE-OH
C[C@@H](O)c1ccc2c(c1)N(CCCN(C)C)c1ccccc1S2
|
C19H24N2OS 328.481000 |
ZIJWCRNUEBJMSQ-CQSZACIVSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB10
|
Local ready
Direct docking supported
|
|
E3L067376
LIG001946
|
14i
O=C1CCC(CSc2ccccc2[N+](=O)[O-])C(=O)N1
|
C12H12N2O4S 280.305000 |
ZJHBTYOIMUAONL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50625127; MolGlueDB:MGDB940
|
Local ready
Direct docking supported
|
|
E3L067377
LIG001947
|
14
O=C1CCC(N2C(=O)c3ccc(N4CC5(CNC5)C4)cc3C2=O)C(=O)N1
|
C18H18N4O4 354.366000 |
ZJRIIJGHSAJWMI-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1003
|
Local ready
Direct docking supported
|
|
E3L067378
LIG001948
|
13
CCCCCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C19H23N3O4 357.410000 |
ZKGUWWBEGKHGOY-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1281
|
Local ready
Direct docking supported
|
|
E3L067379
LIG001949
|
6
O=C1CCC(N2Cc3cc(CNC(=O)c4ccc(F)cc4)ccc3C2=O)C(=O)N1
|
C21H18FN3O4 395.390000 |
ZKKBMXPIWFMOKF-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1055
|
Local ready
Direct docking supported
|
|
E3L067380
LIG001950
|
GBD-6
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@H]1CCCN(C(=O)CCCCCCCNc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)C1
|
C43H45N9O6 783.890000 |
ZKOLOVUMLBKGOH-YCIOTGQKSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB839
|
Local ready
Direct docking supported
|
|
E3L067381
LIG001951
|
cpmd 3
O=C1CCC(N2Cc3cc(C4CCCCC4)ccc3C2=O)C(=O)N1
|
C19H22N2O3 326.396000 |
ZKRGLGRCJCCCBW-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1175
|
Local ready
Direct docking supported
|
|
E3L067382
LIG001952
|
JQ1-AcQ
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H]1CCC(=O)NC1=O)c1nnc(C)n1-2
|
C36H45ClN8O5S 737.327000 |
ZLPNUFSEIVRDOK-KWTBFXGESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB260
|
Local ready
Direct docking supported
|
|
E3L067383
LIG001953
|
ZXH-1-156
CC(=O)c1ccc(C2N=C(Nc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C=CN2)cc1
|
C25H23N5O4 457.490000 |
ZLQHIPQPTSJASJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB48
|
Local ready
Direct docking supported
|
|
E3L067384
LIG001954
|
F-Le
Nc1cc(F)cc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C13H12FN3O3 277.255000 |
ZLSXUIDRXBLOLG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB794
|
Local ready
Direct docking supported
|
|
E3L067385
LIG001955
|
Entry 19
CN1CCN([C@@H]2CCCN(c3cnc(C(N)=O)c(Nc4ccc(N5CC6(C5)CN(c5ccc7c(c5)C(=O)N(C5CCC(=O)NC5=O)C7=O)C6)cc4)n3)C2)C1=O
|
C38H41N11O6 747.817000 |
ZLZHJUUEUPUMNH-RXVAYIKUSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB573
|
Local ready
Direct docking supported
|
|
E3L067386
LIG001956
|
44
CC(=O)N1CCN(c2cc3c(cc2F)C(=O)N(C2CCC(=O)NC2=O)C3=O)CC1
|
C19H19FN4O5 402.382000 |
ZMDBRAWGJMRYFZ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB62
|
Local ready
Direct docking supported
|
|
E3L067387
LIG001957
|
LYG-107
Cc1ccc(C/C(=N\O)C(=O)Nc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1Cl
|
C23H19ClN4O6 482.880000 |
ZMYWIWBZKNOHOS-WPWMEQJKSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1326
|
Local ready
Direct docking supported
|