| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007161
BDB007161
|
BDBM161207
Cc1c(C)n(Cc2ccc(F)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3ccc(C(C)(C)C)cc3)cc12
|
C33H37FN2O4 544.667000 |
UOROYSIXQQDIFM-UNMCSNQZSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM161207; PubChem:CID71075794
|
Local ready
Direct docking supported
|
|
E3L007162
BDB007162
|
BDBM161208
Cc1c(C)n(Cc2ccc(F)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(C4CC4)c3)cc12
|
C32H33FN2O4 528.624000 |
JFOOVABXXMXZLB-FPOVZHCZSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM161208; PubChem:CID71075601
|
Local ready
Direct docking supported
|
|
E3L007163
BDB007163
|
BDBM161212
Cc1c(C)n(Cc2cccc(C3(C(=O)O)CC3)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(C4CC4)c3)cc12
|
C33H34N2O3 506.646000 |
BKVYSZWMHVHMRG-NRFANRHFSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM161212; PubChem:CID71075655
|
Local ready
Direct docking supported
|
|
E3L007164
BDB007164
|
BDBM161213
Cc1c(C)n(Cc2cccc(C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(C4CC4)c3)cc12
|
C30H30N2O3 466.581000 |
YMXRPPNTNMQOFL-IBGZPJMESA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM161213; PubChem:CID71075453
|
Local ready
Direct docking supported
|
|
E3L007165
BDB007165
|
BDBM161215
COc1ccc(Cn2c(C)c(C)c3cc(C(=O)N[C@@H](C)c4cccc(C(C)C)c4)ccc32)cc1O[C@@H](C)C(=O)O
|
C33H38N2O5 542.676000 |
RNMNXSJKLFRDSO-GMAHTHKFSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM161215; PubChem:CID71075314
|
Local ready
Direct docking supported
|
|
E3L007166
BDB007166
|
BDBM161648
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1
|
C28H31ClN2O3 479.020000 |
WFSJVHLKSNYJNJ-KUFXBUICSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161648; PubChem:CID53262603
|
Local ready
Direct docking supported
|
|
E3L007167
BDB007167
|
BDBM161682
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1NC(N)=O
|
C29H33ClN4O4 537.060000 |
CNJDIPUBVSAEKF-WPUOIDIFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161682; PubChem:CID53262604
|
Local ready
Direct docking supported
|
|
E3L007168
BDB007168
|
BDBM161686
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1NC(=O)NC
|
C30H35ClN4O4 551.087000 |
MEMPXHHRCPTSPQ-QHSQBYJISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161686; PubChem:CID53262649
|
Local ready
Direct docking supported
|
|
E3L007169
BDB007169
|
BDBM161687
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1NC(C)=O
|
C30H34ClN3O4 536.072000 |
CGHWWFPSIJEUJL-VITKDRCNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161687; PubChem:CID53262650
|
Local ready
Direct docking supported
|
|
E3L007170
BDB007170
|
BDBM161688
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1N(C)C
|
C30H36ClN3O3 522.089000 |
UCGICFRBXLRKKA-HZRSZRRBSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161688; PubChem:CID58438094
|
Local ready
Direct docking supported
|
|
E3L007171
BDB007171
|
BDBM161689
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1C(N)=O
|
C29H32ClN3O4 522.045000 |
YXFUXFRGJVZDGR-WPUOIDIFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161689; PubChem:CID58437689
|
Local ready
Direct docking supported
|
|
E3L007172
BDB007172
|
BDBM161694
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1CO
|
C29H33ClN2O4 509.046000 |
JIQILQRONOEITE-QHSQBYJISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161694; PubChem:CID53262651
|
Local ready
Direct docking supported
|
|
E3L007173
BDB007173
|
BDBM161695
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1CN
|
C29H34ClN3O3 508.062000 |
ZDRUXXFMVAAUQM-QHSQBYJISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161695; PubChem:CID58437776
|
Local ready
Direct docking supported
|
|
E3L007174
BDB007174
|
BDBM161696
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1CNC(C)=O
|
C31H36ClN3O4 550.099000 |
APSINCLWOMYKMT-MFUYNUFSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161696; PubChem:CID58437631
|
Local ready
Direct docking supported
|
|
E3L007175
BDB007175
|
BDBM161703
CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)N(c1ccc(C)cc1OCCCN1CCOCC1)C(=O)C2
|
C33H39ClN2O5 579.137000 |
KBSIRPIXPFGKMT-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161703; PubChem:CID58437764
|
Local ready
Direct docking supported
|
|
E3L007176
BDB007176
|
BDBM161708
CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)N(c1ccc(C)cc1OCC(=O)O)C(=O)C2
|
C28H28ClNO6 509.986000 |
RWFZJJVATFIDJU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161708; PubChem:CID58437795
|
Local ready
Direct docking supported
|
|
E3L007177
BDB007177
|
BDBM161710
CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)N(c1ccc(C)cc1OCc1nn[nH]n1)C(=O)C2
|
C28H28ClN5O4 534.016000 |
FOCZOWVAISYOAB-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161710; PubChem:CID53262652
|
Local ready
Direct docking supported
|
|
E3L007178
BDB007178
|
BDBM161723
CC[C@@H](C)Oc1cc2c(cc1OC)NC(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1
|
C27H30ClN3O3 480.008000 |
PLFZIENRXZPGRC-SIHBAMTISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161723; PubChem:CID53261667
|
Local ready
Direct docking supported
|
|
E3L007179
BDB007179
|
BDBM161731
COc1ccc(N2C(=O)Nc3cc(OC)c(OC)cc3C2c2ccc(Cl)cc2)cc1
|
C23H21ClN2O4 424.884000 |
UXMFFRFGEASXKL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161731; PubChem:CID53261668
|
Local ready
Direct docking supported
|
|
E3L007180
BDB007180
|
BDBM161733
CC[C@@H](C)Oc1cc2c(cc1OC)N(C)C(=O)N(c1ccc(N(C)C)cc1)C2c1ccc(Cl)cc1
|
C28H32ClN3O3 494.035000 |
ICTSOMVZHLHDMW-XZATXCMXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161733; PubChem:CID53261669
|
Local ready
Direct docking supported
|