| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007201
BDB007201
|
BDBM161872
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(CC3CCCC3)C(C)=O)cc1)C2c1ccc(Cl)cc1
|
C34H39ClN2O4 575.149000 |
HCKIIIXWNXBFTC-PVFJFFHYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161872; PubChem:CID58437862
|
Local ready
Direct docking supported
|
|
E3L007202
BDB007202
|
BDBM161874
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCCNC3)cc1)C2c1ccc(Cl)cc1
|
C33H40ClN3O3 562.154000 |
RMGSYAJRAGOIFI-PPFXIRLKSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161874; PubChem:CID58438004
|
Local ready
Direct docking supported
|
|
E3L007203
BDB007203
|
BDBM161875
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCCN(C)C3)cc1)C2c1ccc(Cl)cc1
|
C34H42ClN3O3 576.181000 |
FMWULHHMNFVCEP-MPFIGGLTSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161875; PubChem:CID58438177
|
Local ready
Direct docking supported
|
|
E3L007204
BDB007204
|
BDBM161876
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCNCC3)cc1)C2c1ccc(Cl)cc1
|
C33H40ClN3O3 562.154000 |
NCDHHXTYFKEITD-LWMFVPLKSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161876; PubChem:CID67390247
|
Local ready
Direct docking supported
|
|
E3L007205
BDB007205
|
BDBM161877
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCN(C(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
|
C35H42ClN3O4 604.191000 |
KCHWGOINQZGMEL-MMHRDOBHSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161877; PubChem:CID58437782
|
Local ready
Direct docking supported
|
|
E3L007206
BDB007206
|
BDBM161878
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCN(S(C)(=O)=O)CC3)cc1)C2c1ccc(Cl)cc1
|
C34H42ClN3O5S 640.246000 |
NQKUMYQVZUUXRL-KJLUBMIJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161878; PubChem:CID58437838
|
Local ready
Direct docking supported
|
|
E3L007207
BDB007207
|
BDBM161879
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)CC3CCN(C(=O)N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
|
C36H45ClN4O4 633.233000 |
UGPJKFXFWRTNJI-YAYCPNDQSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161879; PubChem:CID58438048
|
Local ready
Direct docking supported
|
|
E3L007208
BDB007208
|
BDBM161880
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@H]3CC[C@H](N)CC3)cc1)C2c1ccc(Cl)cc1
|
C34H42ClN3O3 576.181000 |
NKIPMVCPPOTZLF-TWZRQJNISA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM161880
|
Local ready
Direct docking supported
|
|
E3L007209
BDB007209
|
BDBM161882
CCN[C@H]1CC[C@H](CN(C)c2ccc(N3C(=O)Cc4cc(OC)c(O[C@H](C)CC)cc4C3c3ccc(Cl)cc3)cc2)CC1
|
C36H46ClN3O3 604.235000 |
NHJBFVAZLNVPEB-GYNNIAEXSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM161882
|
Local ready
Direct docking supported
|
|
E3L007210
BDB007210
|
BDBM161883
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)CC)CC3)cc1)C2c1ccc(Cl)cc1
|
C37H48ClN3O3 618.262000 |
FNFFGCOHCCHIDU-IHDHMKHVSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM161883
|
Local ready
Direct docking supported
|
|
E3L007211
BDB007211
|
BDBM161941
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCCC3)cc1)C2c1ccc(Cl)cc1
|
C32H37ClN2O3 533.112000 |
LBHRNHIJVFKNRX-XOBGVXBPSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161941; PubChem:CID58438299
|
Local ready
Direct docking supported
|
|
E3L007212
BDB007212
|
BDBM161944
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCOCC3)cc1)C2c1ccc(Cl)cc1
|
C32H37ClN2O4 549.111000 |
RSKLVMJITCOSKY-XOBGVXBPSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161944; PubChem:CID58438032
|
Local ready
Direct docking supported
|
|
E3L007213
BDB007213
|
BDBM161945
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)O)cc1)C2c1ccc(Cl)cc1
|
C28H30ClNO4 480.004000 |
ALFZUDGOPZPEEV-JKTWZELDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161945; PubChem:CID58437836
|
Local ready
Direct docking supported
|
|
E3L007214
BDB007214
|
BDBM161948
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(CC)C(=O)C3CCN(C(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
|
C38H46ClN3O5 660.255000 |
WGYKJEFTTXDLPM-YFTDMWITSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161948; PubChem:CID58437629
|
Local ready
Direct docking supported
|
|
E3L007215
BDB007215
|
BDBM161949
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(CC)C(=O)C3CCNCC3)cc1)C2c1ccc(Cl)cc1
|
C36H44ClN3O4 618.218000 |
CQVINMJHLMFOCD-BKCPDIIESA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161949; PubChem:CID58438260
|
Local ready
Direct docking supported
|
|
E3L007216
BDB007216
|
BDBM161951
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)NC3CCNCC3)cc1)C2c1ccc(Cl)cc1
|
C33H40ClN3O3 562.154000 |
KHAYFXPJPHDPRJ-KGUSEGQSSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161951; PubChem:CID67390141
|
Local ready
Direct docking supported
|
|
E3L007217
BDB007217
|
BDBM161953
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C(C)=O)C3CCNCC3)cc1)C2c1ccc(Cl)cc1
|
C35H42ClN3O4 604.191000 |
VGLGNSRSXLUAAG-XFBJNOSPSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161953; PubChem:CID67394007
|
Local ready
Direct docking supported
|
|
E3L007218
BDB007218
|
BDBM161954
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C)C3CCNCC3)cc1)C2c1ccc(Cl)cc1
|
C34H42ClN3O3 576.181000 |
OQQLKHVTFRESEW-MHJPDIQUSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161954; PubChem:CID67390238
|
Local ready
Direct docking supported
|
|
E3L007219
BDB007219
|
BDBM161955
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C)[C@H]3CC[C@@H](N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
|
C37H48ClN3O3 618.262000 |
BGCDTIWRARQPOE-XHNXYWIKSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM161955
|
Local ready
Direct docking supported
|
|
E3L007220
BDB007220
|
BDBM161958
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N(C(C)=O)[C@H]3CC[C@@H](N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
|
C38H48ClN3O4 646.272000 |
ONMJYQXUYIFABX-IQHHHHCESA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM161958
|
Local ready
Direct docking supported
|