| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007221
BDB007221
|
BDBM161959
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N[C@H]3CC[C@H](N)CC3)cc1)C2c1ccc(Cl)cc1
|
C34H42ClN3O3 576.181000 |
WDKPXBMAYNJPHO-QNKJKVLSSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM161959
|
Local ready
Direct docking supported
|
|
E3L007222
BDB007222
|
BDBM161961
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCC(N(C)C)CC3)cc1)C2c1ccc(Cl)cc1
|
C35H44ClN3O3 590.208000 |
GYPIVOQVWAXHTL-BKCPDIIESA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161961; PubChem:CID58437663
|
Local ready
Direct docking supported
|
|
E3L007223
BDB007223
|
BDBM161964
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCC(N(C)C(C)C)CC3)cc1)C2c1ccc(Cl)cc1
|
C37H48ClN3O3 618.262000 |
JHUAOSPKENTLLI-BPQYTBSDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161964; PubChem:CID58438310
|
Local ready
Direct docking supported
|
|
E3L007224
BDB007224
|
BDBM161965
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCC(NC(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
|
C35H42ClN3O4 604.191000 |
WKPFGADMDMLPOJ-XFBJNOSPSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161965; PubChem:CID58438263
|
Local ready
Direct docking supported
|
|
E3L007225
BDB007225
|
BDBM161966
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCN(C(C)=O)CC3)cc1)C2c1ccc(Cl)cc1
|
C34H40ClN3O4 590.164000 |
OXJJQMUURYIRHE-MHJPDIQUSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161966; PubChem:CID58437810
|
Local ready
Direct docking supported
|
|
E3L007226
BDB007226
|
BDBM162021
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(C)N3CCOCC3=O)cc1)C2c1ccc(Cl)cc1
|
C32H35ClN2O5 563.094000 |
JGOSSRBMKCJJIY-DHFMJDSQSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM162021; PubChem:CID58438109
|
Local ready
Direct docking supported
|
|
E3L007227
BDB007227
|
BDBM162023
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)C)CC3)cc1)[C@H]2c1ccc(Cl)cc1
|
C36H46ClN3O3 604.235000 |
IXFIHZIZFSCBSU-UVAXCULCSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162023
|
Local ready
Direct docking supported
|
|
E3L007228
BDB007228
|
BDBM162052
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N(C)C)CC3)cc1)C(=O)C2
|
C35H44ClN3O3 590.208000 |
USOMPACWXVKBTM-NYRHXDHDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162052
|
Local ready
Direct docking supported
|
|
E3L007229
BDB007229
|
BDBM162058
CCCCNC(=O)O[C@@H](C)/C=C\C(=O)N[C@H]1CO[C@@H](C/C=C(C)/C=C/[C@@H]2C[C@]3(CO3)CC(C)(C)O2)OC1
|
C28H44N2O7 520.667000 |
NIVOIQBBOZRMAS-RWGRZISVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162058
|
Local ready
Direct docking supported
|
|
E3L007230
BDB007230
|
BDBM162059
CCN(CC)C(=O)O[C@@H](C)/C=C\C(=O)N[C@H]1CO[C@@H](C/C=C(C)/C=C/[C@@H]2C[C@]3(CO3)CC(C)(C)O2)OC1
|
C28H44N2O7 520.667000 |
JYQISZNEUXUGQQ-AVOIVTMUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162059
|
Local ready
Direct docking supported
|
|
E3L007231
BDB007231
|
BDBM162060
CC(/C=C/[C@@H]1C[C@]2(CO2)CC(C)(C)O1)=C\C[C@H]1OC[C@@H](NC(=O)/C=C\[C@H](C)OC(=O)NC(C)(C)C)CO1
|
C28H44N2O7 520.667000 |
IPGDELGCMVFYFB-ITFYNRAJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162060
|
Local ready
Direct docking supported
|
|
E3L007232
BDB007232
|
BDBM162061
CCN(C[C@H]1CC[C@H](N(C)C)CC1)c1ccc(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3[C@@H]2c2ccc(Cl)cc2)cc1
|
C36H46ClN3O3 604.235000 |
XGTLWYWQZIIKPV-GDLCEAIKSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162061
|
Local ready
Direct docking supported
|
|
E3L007233
BDB007233
|
BDBM162062
CCCN(C)C(=O)O[C@@H](C)/C=C\C(=O)N[C@H]1CO[C@@H](C/C=C(C)/C=C/[C@@H]2C[C@]3(CO3)CC(C)(C)O2)OC1
|
C28H44N2O7 520.667000 |
PTFWZADSBAPJRO-RWGRZISVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162062
|
Local ready
Direct docking supported
|
|
E3L007234
BDB007234
|
BDBM162063
COCCNC(=O)O[C@@H](C)/C=C\C(=O)N[C@H]1CO[C@@H](C/C=C(C)/C=C/[C@@H]2C[C@]3(CO3)CC(C)(C)O2)OC1
|
C27H42N2O8 522.639000 |
LDYOEOZYCXXRPG-XSPZFIGHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162063
|
Local ready
Direct docking supported
|
|
E3L007235
BDB007235
|
BDBM162064
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](NS(C)(=O)=O)CC3)cc1)C(=O)C2
|
C34H42ClN3O5S 640.246000 |
RTXBFXPWNNENIR-PGWXNWGFSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162064
|
Local ready
Direct docking supported
|
|
E3L007236
BDB007236
|
BDBM162065
CCCCN(C)C(=O)O[C@@H](C)/C=C\C(=O)N[C@H]1CO[C@@H](C/C=C(C)/C=C/[C@@H]2C[C@]3(CO3)CC(C)(C)O2)OC1
|
C29H46N2O7 534.694000 |
PXEQLPNSWGPKSP-JQKKSWGYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162065
|
Local ready
Direct docking supported
|
|
E3L007237
BDB007237
|
BDBM162066
CC(/C=C/[C@@H]1C[C@]2(CO2)CC(C)(C)O1)=C\C[C@H]1OC[C@@H](NC(=O)/C=C\[C@H](C)OC(=O)N(C)C(C)C)CO1
|
C28H44N2O7 520.667000 |
HWFXRPFSEMUHMI-RWGRZISVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162066
|
Local ready
Direct docking supported
|
|
E3L007238
BDB007238
|
BDBM162067
CC(/C=C/[C@@H]1C[C@]2(CO2)CC(C)(C)O1)=C\C[C@H]1OC[C@@H](NC(=O)/C=C\[C@H](C)OC(=O)N(C)C(C)(C)C)CO1
|
C29H46N2O7 534.694000 |
MSBXZHDPQZMJMG-NJWWTUQPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162067
|
Local ready
Direct docking supported
|
|
E3L007239
BDB007239
|
BDBM162068
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](NC(=O)c4cocn4)CC3)cc1)C(=O)C2
|
C37H41ClN4O5 657.211000 |
OIRZEYYFCUVARK-BXKNEMSHSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162068
|
Local ready
Direct docking supported
|
|
E3L007240
BDB007240
|
BDBM162069
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCNC(=O)C4)CC3)cc1)C(=O)C2
|
C37H45ClN4O4 645.244000 |
BZZYIHQWCXHSMZ-FMSKOOSDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162069
|
Local ready
Direct docking supported
|