| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007181
BDB007181
|
BDBM161740
COc1ccc(N2C(=O)Cc3cc(OCCN4CCOCC4)c(OC)cc3C2c2ccc(Cl)cc2)cc1
|
C29H31ClN2O5 523.029000 |
AKPFFHYQTZCFGK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161740; PubChem:CID53261670
|
Local ready
Direct docking supported
|
|
E3L007182
BDB007182
|
BDBM161744
COc1ccc(N2C(=O)Cc3cc(OCCN)c(OC)cc3C2c2ccc(Cl)cc2)cc1
|
C25H25ClN2O4 452.938000 |
SPROQMZYTFZBOG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161744; PubChem:CID58437931
|
Local ready
Direct docking supported
|
|
E3L007183
BDB007183
|
BDBM161745
CCOc1cc2c(cc1O[C@H](C)CC)C(c1ccc(Cl)cc1)N(c1ccc(OC)cc1)C(=O)C2
|
C28H30ClNO4 480.004000 |
LFLACZRNZALIIF-KUFXBUICSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161745; PubChem:CID58438009
|
Local ready
Direct docking supported
|
|
E3L007184
BDB007184
|
BDBM161750
CC[C@@H](C)Oc1cc2c(cc1OCC(=O)N1CCN(C)CC1)CC(=O)N(c1ccc(OC)cc1)C2c1ccc(Cl)cc1
|
C33H38ClN3O5 592.136000 |
NQDGYXBFKYQRNB-LWMFVPLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161750; PubChem:CID58438271
|
Local ready
Direct docking supported
|
|
E3L007185
BDB007185
|
BDBM161752
CCCOc1cc2c(cc1OC)CC(=O)N(c1ccc(OC)cc1)C2c1ccc(Cl)cc1
|
C26H26ClNO4 451.950000 |
NOYJBYLOPGFUMF-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161752; PubChem:CID58437639
|
Local ready
Direct docking supported
|
|
E3L007186
BDB007186
|
BDBM161755
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(OC)cc1)C2c1ccc(Cl)cc1
|
C27H28ClNO4 465.977000 |
GQUCZUQLQVPONT-MOJDWNGGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161755; PubChem:CID58437850
|
Local ready
Direct docking supported
|
|
E3L007187
BDB007187
|
BDBM161756
COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(c1ccc(N(C)C)cc1)C(=O)C2
|
C27H29ClN2O3 464.993000 |
FSLIGGSDKPKMAE-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161756; PubChem:CID53261723
|
Local ready
Direct docking supported
|
|
E3L007188
BDB007188
|
BDBM161802
CC(C)Nc1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2
|
C31H31ClN4O 511.069000 |
PCLOGHHCVDXJJD-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM161802; PubChem:CID58438064
|
Local ready
Direct docking supported
|
|
E3L007189
BDB007189
|
BDBM161812
CCC(=O)Nc1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2
|
C31H29ClN4O2 525.052000 |
LXXWMRDUHMJDSX-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161812; PubChem:CID58438270
|
Local ready
Direct docking supported
|
|
E3L007190
BDB007190
|
BDBM161813
CCCN(c1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2)C(C)C
|
C34H37ClN4O 553.150000 |
CAGZMCSXFPQMPM-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161813; PubChem:CID58437745
|
Local ready
Direct docking supported
|
|
E3L007191
BDB007191
|
BDBM161814
CC(C)N(CCN(C)C)c1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2
|
C35H40ClN5O 582.192000 |
VVDDORQGXUJPER-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161814; PubChem:CID58437617
|
Local ready
Direct docking supported
|
|
E3L007192
BDB007192
|
BDBM161817
CC(=O)NCCN(c1ccc2c(c1)C(c1ccc(Cl)cc1)N(c1ccc(N(C)Cc3ccncc3)cc1)C(=O)C2)C(C)C
|
C35H38ClN5O2 596.175000 |
LWFLQMUHUMIQJZ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161817; PubChem:CID67391326
|
Local ready
Direct docking supported
|
|
E3L007193
BDB007193
|
BDBM161836
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N3CCCC3=O)cc1)C2c1ccc(Cl)cc1
|
C30H31ClN2O4 519.041000 |
DERUQPZTBLGCOC-HZRSZRRBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161836; PubChem:CID58437979
|
Local ready
Direct docking supported
|
|
E3L007194
BDB007194
|
BDBM161840
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(-n3cccn3)cc1)C2c1ccc(Cl)cc1
|
C29H28ClN3O3 502.014000 |
SMESOWQZCFBECR-COBFLCELSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161840; PubChem:CID58438259
|
Local ready
Direct docking supported
|
|
E3L007195
BDB007195
|
BDBM161841
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(-c3cn[nH]c3)cc1)C2c1ccc(Cl)cc1
|
C29H28ClN3O3 502.014000 |
SXFXYYOGQWUAAF-QHSQBYJISA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161841; PubChem:CID58438142
|
Local ready
Direct docking supported
|
|
E3L007196
BDB007196
|
BDBM161845
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(=O)N(C)CC)cc1)C2c1ccc(Cl)cc1
|
C30H33ClN2O4 521.057000 |
KMDWMNNOGQIKKJ-COBFLCELSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161845; PubChem:CID58437957
|
Local ready
Direct docking supported
|
|
E3L007197
BDB007197
|
BDBM161849
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(C(=O)N3C[C@H](O)C[C@H]3C(=O)NC)cc1)C2c1ccc(Cl)cc1
|
C33H36ClN3O6 606.119000 |
HFUSQVKFLQGXMK-YWDHBOEBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161849; PubChem:CID58437691
|
Local ready
Direct docking supported
|
|
E3L007198
BDB007198
|
BDBM161863
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(CO)cc1)C2c1ccc(Cl)cc1
|
C27H28ClNO4 465.977000 |
JJLIBSXLCMDFQN-MOJDWNGGSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161863; PubChem:CID58438241
|
Local ready
Direct docking supported
|
|
E3L007199
BDB007199
|
BDBM161864
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)Cc3ccncc3)cc1)C2c1ccc(Cl)cc1
|
C33H34ClN3O3 556.106000 |
RNOXGLRIZIHGIA-LWMFVPLKSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161864; PubChem:CID58438206
|
Local ready
Direct docking supported
|
|
E3L007200
BDB007200
|
BDBM161868
CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C(C)=O)cc1)C2c1ccc(Cl)cc1
|
C29H31ClN2O4 507.030000 |
VHKNQTVTMKLMIT-QHSQBYJISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM161868; PubChem:CID58437723
|
Local ready
Direct docking supported
|