| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007241
BDB007241
|
BDBM162070
CC(/C=C/[C@@H]1C[C@]2(CO2)CC(C)(C)O1)=C\C[C@H]1OC[C@@H](NC(=O)/C=C\[C@H](C)OC(=O)N(C)C)CO1
|
C26H40N2O7 492.613000 |
VCOKAORBULPQML-SYFPBJIXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162070
|
Local ready
Direct docking supported
|
|
E3L007242
BDB007242
|
BDBM162071
CNC(=O)O[C@@H](C)/C=C\C(=O)N[C@H]1CO[C@@H](C/C=C(C)/C=C/[C@@H]2C[C@]3(CO3)CC(C)(C)O2)OC1
|
C25H38N2O7 478.586000 |
LKIFWBJHXYDKCY-SZSNWZDOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162071
|
Local ready
Direct docking supported
|
|
E3L007243
BDB007243
|
BDBM162072
COC(=O)CN(C)[C@H]1CC[C@H](CN(C)c2ccc(N3C(=O)Cc4cc(OC)c(OC(C)C)cc4[C@@H]3c3ccc(Cl)cc3)cc2)CC1
|
C37H46ClN3O5 648.244000 |
DQPJNDSODCBHII-YFMCWZQFSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162072
|
Local ready
Direct docking supported
|
|
E3L007244
BDB007244
|
BDBM162073
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCOCC4)CC3)cc1)C(=O)C2
|
C37H46ClN3O4 632.245000 |
JKUYVRHPBGUSAR-BYSGAPJBSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162073
|
Local ready
Direct docking supported
|
|
E3L007245
BDB007245
|
BDBM162074
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)NCC4=O)CC3)cc1)C(=O)C2
|
C37H43ClN4O5 659.227000 |
FEHXUXUSVXBRGS-HXNRPOFDSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162074
|
Local ready
Direct docking supported
|
|
E3L007246
BDB007246
|
BDBM162075
CC(/C=C/[C@@H]1C[C@]2(CO2)CC(C)(C)O1)=C\C[C@H]1OC[C@@H](NC(=O)/C=C\[C@H](C)OC(N)=O)CO1
|
C24H36N2O7 464.559000 |
IGHYLOLSQMGLKN-IBZCDZKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162075
|
Local ready
Direct docking supported
|
|
E3L007247
BDB007247
|
BDBM162076
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N(CC(N)=O)CC(N)=O)CC3)cc1)C(=O)C2
|
C37H46ClN5O5 676.258000 |
IWXOKKNAMZZBTO-HXNRPOFDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162076
|
Local ready
Direct docking supported
|
|
E3L007248
BDB007248
|
BDBM162077
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCCNC(=O)C4)CC3)cc1)C(=O)C2
|
C38H47ClN4O4 659.271000 |
ZAZFOLVUBZCAKF-IIPSPAQQSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162077
|
Local ready
Direct docking supported
|
|
E3L007249
BDB007249
|
BDBM162090
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc([C@H](C)N3CCS(=O)(=O)CC3)cc1)C(=O)C2
|
C31H35ClN2O5S 583.150000 |
CGHAZAYVAWAEEP-BGOLNKOXSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM162090; PubChem:CID58438050
|
Local ready
Direct docking supported
|
|
E3L007250
BDB007250
|
BDBM162092
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc([C@H](C)N3CCN(C(C)=O)CC3)cc1)C(=O)C2
|
C33H38ClN3O4 576.137000 |
JVNRCKRWFKVINQ-KATKFWMUSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM162092; PubChem:CID58438139
|
Local ready
Direct docking supported
|
|
E3L007251
BDB007251
|
BDBM162096
CNC(=O)[C@H]1CCCN1[C@@H](C)c1ccc(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3[C@@H]2c2ccc(Cl)cc2)cc1
|
C33H38ClN3O4 576.137000 |
OBJVMDJHVUAQEF-IWNCIYCBSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM162096; PubChem:CID58437725
|
Local ready
Direct docking supported
|
|
E3L007252
BDB007252
|
BDBM162100
COC(=O)[C@@H]1CCCN1[C@@H](C)c1ccc(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3[C@@H]2c2ccc(Cl)cc2)cc1
|
C33H37ClN2O5 577.121000 |
TZTVTMGZQVEMTM-PGRZUCIQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM162100; PubChem:CID58437961
|
Local ready
Direct docking supported
|
|
E3L007253
BDB007253
|
BDBM162104
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C(=O)[C@H]3CC[C@H](N(C)C)CC3)cc1)C(=O)C2
|
C35H42ClN3O4 604.191000 |
NCFWLCHCOYXXLD-BVLDHWHNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM162104
|
Local ready
Direct docking supported
|
|
E3L007254
BDB007254
|
BDBM162107
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(C(C)CN3CCC(N(C)C)CC3)cc1)C(=O)C2
|
C35H44ClN3O3 590.208000 |
FOWSNFVTTAEKAG-KMXYMDJGSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM162107; PubChem:CID58438033
|
Local ready
Direct docking supported
|
|
E3L007255
BDB007255
|
BDBM162112
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(C(C)C(=O)N3CCC(N(C)C)CC3)cc1)C(=O)C2
|
C35H42ClN3O4 604.191000 |
YJNAVDANBICIEK-IYXVLPAFSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM162112; PubChem:CID58438089
|
Local ready
Direct docking supported
|
|
E3L007256
BDB007256
|
BDBM162113
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(Cn3ccnc3)cc1)C(=O)C2
|
C29H28ClN3O3 502.014000 |
AZTLSCFOQHSCPJ-LJAQVGFWSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM162113; PubChem:CID58437797
|
Local ready
Direct docking supported
|
|
E3L007257
BDB007257
|
BDBM162120
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCNC(=O)C4)CC3)cc1OC)C(=O)C2
|
C38H47ClN4O5 675.270000 |
UUIBRRARLBWRNX-JUPNEIPRSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162120
|
Local ready
Direct docking supported
|
|
E3L007258
BDB007258
|
BDBM162122
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CC(=O)N(C)C4)CC3)cc1)C(=O)C2
|
C37H45ClN4O4 645.244000 |
MWFWTELIAOKJOB-FMSKOOSDSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162122
|
Local ready
Direct docking supported
|
|
E3L007259
BDB007259
|
Nvp-cgm097
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)CC3CCC(N4CCN(C)C(=O)C4)CC3)cc1)C(=O)C2
|
C38H47ClN4O4 659.271000 |
CLRSLRWKONPSRQ-CPOWQTMSSA-N | O15151, P98170, Q00987, Q13490 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2, Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM162123; PubChem:CID53240420
|
Local ready
Direct docking supported
|
|
E3L007260
BDB007260
|
BDBM162130
COc1cc2c(cc1OC(C)C)[C@H](c1ccc(Cl)cc1)N(c1ccc(N(C)C[C@H]3CC[C@H](N4CCN(C(C)=O)CC4)CC3)cc1)C(=O)C2
|
C39H49ClN4O4 673.298000 |
APSUZVQSZZIWSY-UBFXLBCASA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB
BindingDB:BDBM162130
|
Local ready
Direct docking supported
|