| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L009881
BDB009881
|
BDBM215400
CCOc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H26F3N5O3 525.531000 |
PVLCKDWSZHYWEE-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215400; PubChem:CID90319806
|
Local ready
Direct docking supported
|
|
E3L009882
BDB009882
|
BDBM215401
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](Cn2c(=O)[nH]c3ccccc32)C2CC2)C1=O
|
C32H31Cl2N3O4 592.523000 |
AQTZCVIWKNQTOK-SADHMGQBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215401; PubChem:CID67999514
|
Local ready
Direct docking supported
|
|
E3L009883
BDB009883
|
BDBM215402
CCc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H26F3N5O2 509.532000 |
UMGWZBZRKBIUBJ-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215402; PubChem:CID90325021
|
Local ready
Direct docking supported
|
|
E3L009884
BDB009884
|
BDBM215403
C=CC[C@@]1(C)C[C@H](c2ccc(F)c(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(C)C)C1=O
|
C24H26Cl2FNO 434.382000 |
YHYSTAWTWVPGTO-CKUXNOBLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215403; PubChem:CID58573371
|
Local ready
Direct docking supported
|
|
E3L009885
BDB009885
|
BDBM215404
CC(C)N1C(=O)[C@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C23H24Cl2FNO3 452.353000 |
SXIGYXSZWFJBLE-LSWJPFSZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215404; PubChem:CID58573490
|
Local ready
Direct docking supported
|
|
E3L009886
BDB009886
|
BDBM215405
CC[C@@H](CNS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H31Cl2FN2O5S 573.514000 |
RCKXSJGZRPHAKO-SODSZRCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215405; PubChem:CID68000370
|
Local ready
Direct docking supported
|
|
E3L009887
BDB009887
|
BDBM215406
CC[C@@H](CN(C)S(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H33Cl2FN2O5S 587.541000 |
LTUHSZJIRQEHAV-CXQACEEJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215406; PubChem:CID58573171
|
Local ready
Direct docking supported
|
|
E3L009888
BDB009888
|
BDBM215407
CC[C@@H](CS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C25H28Cl2FNO5S 544.472000 |
VTWWVNIKLCSIRM-KWLZBDKBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215407; PubChem:CID58573496
|
Local ready
Direct docking supported
|
|
E3L009889
BDB009889
|
BDBM215408
CC[C@@H](CS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H30Cl2FNO5S 558.499000 |
BPTBYDCAPGEQIF-SODSZRCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215408; PubChem:CID68000629
|
Local ready
Direct docking supported
|
|
E3L009890
BDB009890
|
BDBM215409
CC[C@@H](CS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H30Cl2FNO5S 570.510000 |
KJBVQUFEAVNSSV-OCBXDECUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215409; PubChem:CID67999008
|
Local ready
Direct docking supported
|
|
E3L009891
BDB009891
|
BDBM215410
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H34Cl2FNO5S 586.553000 |
WIRXUNJQOQVNQG-ZJTSJXPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215410; PubChem:CID67998912
|
Local ready
Direct docking supported
|
|
E3L009892
BDB009892
|
BDBM215411
CC[C@@H](CS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H30Cl2N2O5S 553.508000 |
XVYRFRBSGHIKKJ-WRJJBPASSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215411; PubChem:CID58573601
|
Local ready
Direct docking supported
|
|
E3L009893
BDB009893
|
BDBM215412
CC[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H32Cl2FNO5S 572.526000 |
ZMFJOMGQWPWIGR-CXQACEEJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215412; PubChem:CID68000340
|
Local ready
Direct docking supported
|
|
E3L009894
BDB009894
|
BDBM215413
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H34Cl2N2O5S 569.551000 |
KBQKQQVLEHPVQR-CXTNQITHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215413; PubChem:CID58573370
|
Local ready
Direct docking supported
|
|
E3L009895
BDB009895
|
BDBM215414
CC[C@@H](CNS(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H31Cl2N3O5S 568.523000 |
XRUSLSLCODEKLR-WRJJBPASSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215414; PubChem:CID58573456
|
Local ready
Direct docking supported
|
|
E3L009896
BDB009896
|
BDBM215415
CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cncc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H33Cl2N3O5S 582.550000 |
MIUPTLFTXFPAKG-OCBXDECUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215415; PubChem:CID58573738
|
Local ready
Direct docking supported
|
|
E3L009897
BDB009897
|
BDBM215416
CC[C@@H](CS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cn1
|
C25H30Cl2N2O5S 541.497000 |
HHBOCKILPOUPEP-OKHDYOJBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215416; PubChem:CID58573135
|
Local ready
Direct docking supported
|
|
E3L009898
BDB009898
|
BDBM215417
CCOc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5O3 539.558000 |
ODBGKDSEAKTZHO-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215417; PubChem:CID90319938
|
Local ready
Direct docking supported
|
|
E3L009899
BDB009899
|
BDBM215418
CC(C)c1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5O2 523.559000 |
PRMUDUBEKQEVHU-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215418; PubChem:CID90325015
|
Local ready
Direct docking supported
|
|
E3L009900
BDB009900
|
BDBM215419
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(C(C)(C)C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C29H30F3N5O2 537.586000 |
DGILGOIEATZMPP-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215419; PubChem:CID90318387
|
Local ready
Direct docking supported
|